[34] On-line computer analysis of the kinetics of chemiluminescent reactions: Application to luminescent immunoassays

Phenolphthalexon, a compound with iminodiacetic acid as a functional group, has been labelled with 113mIn to high chemical purity and its usefulness in studies of biliary excretion patency has been studied. Organ distribution of 113mIn-phenolphthalexon in mice was characterized by high liver uptake (50.8% of the administered dose after 5 min) and rapid clearance through the gall bladder. An animal model for studying obstruction of biliary excretion has been developed. Data on the kinetics of the radiopharmaceutical were obtained by collecting in-vivo data through an on-line computer.

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Method for on-line prediction of kinetics of alcoholic fermentation in wine making

Journal of Fermentation and Bioengineering ◽

10.1016/0922-338x(89)90061-5 ◽

1989 ◽

Vol 68 (2) ◽

pp. 131-135 ◽

Cited By ~ 13

Author(s):

Nour Eddine El Haloui ◽

Georges Corrieu ◽

Yvon Cleran ◽

Arlette Cheruy

Keyword(s):

Alcoholic Fermentation ◽

Wine Making ◽

On Line ◽

Kinetics Of ◽

Prediction Of Kinetics

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On-line computer analysis of WC-Co structures imaged in a SEM

Metallography ◽

10.1016/0026-0800(79)90044-2 ◽

1979 ◽

Vol 12 (2) ◽

pp. 153-173 ◽

Cited By ~ 5

Author(s):

Tommy Werlefors ◽

Clas Eskilsson

Keyword(s):

Computer Analysis ◽

On Line

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Integration of titrimetric measurement, off-gas analysis and NOx− biosensors to investigate the complexity of denitrification processes

Water Science & Technology ◽

10.2166/wst.2004.0681 ◽

2004 ◽

Vol 50 (11) ◽

pp. 135-141 ◽

Cited By ~ 3

Author(s):

S.H. McMurray ◽

R.L. Meyer ◽

R.J. Zeng ◽

Z. Yuan ◽

J. Keller

Keyword(s):

Nox Reduction ◽

Treatment Plant ◽

Single Step ◽

Gas Analysis ◽

Measuring Process ◽

Nitrogen Gas ◽

Detailed Measurement ◽

On Line ◽

Kinetics Of ◽

Denitrification Process

The denitrification process, namely the reduction of nitrate (NO3−) to nitrogen gas (N2), often cannot be simply modelled as a single step process. For a more complete and comprehensive model the intermediates, particularly nitrite (NO2−) and nitrous oxide (N2O), need to be investigated. This paper demonstrates the integration of titrimetric measurements and off-gas analysis with on-line nitrite plus nitrate (NOx−) biosensors, highlighting the necessity of measuring process intermediates with high time-scale resolution to study and understand the kinetics of denitrification. Investigation of activated sludge from a full-scale treatment plant showed a significant accumulation of NO2−, which appeared to impact on the overall denitrification rate measured as NOx− reduction or N2 production. A different sludge obtained from a lab-scale bioreactor produced N2O instead of N2 as the end product of denitrification. The two examples both illustrate the complexity of denitrification and stress the need for the more versatile and detailed measurement procedures, as presented in this paper.

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On‐Line Computer Analysis and Control of Experiments

Journal of Applied Physics ◽

10.1063/1.1657319 ◽

1969 ◽

Vol 40 (12) ◽

pp. 4948-4953

Author(s):

Roy Kaplow ◽

Harold Posen

Keyword(s):

Computer Analysis ◽

On Line ◽

And Control

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The use of on-line off-gas analyses and stoichiometry in the bio-oxidation kinetics of sulphide minerals

Hydrometallurgy ◽

10.1016/s0304-386x(97)00074-1 ◽

1998 ◽

Vol 48 (1) ◽

pp. 1-26 ◽

Cited By ~ 16

Author(s):

M Boon ◽

K.Ch.A.M Luyben ◽

J.J Heijnen

Keyword(s):

Oxidation Kinetics ◽

Sulphide Minerals ◽

On Line ◽

Kinetics Of

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Mathematical Modeling of Different Molecule Removal on On-Line Haemodiafiltration: Influence of Dialysis Duration and Infusion Flow

Blood Purification ◽

10.1159/000375287 ◽

2015 ◽

Vol 39 (4) ◽

pp. 288-296 ◽

Cited By ~ 7

Author(s):

Francisco Maduell ◽

Juan Sanchez ◽

Marta Net ◽

Miquel Gomez ◽

Jose M. Gonzalez ◽

...

Keyword(s):

Molecular Weight ◽

Treatment Time ◽

Compartment Model ◽

Dialysis Dose ◽

Β2 Microglobulin ◽

Dialysis Duration ◽

Two Compartment Model ◽

On Line ◽

The Impact ◽

Kinetics Of

Background: In a previous study on a nocturnal, every-other-day online haemodiafiltration scheme, different removal patterns were observed for urea, creatinine, β2-microglobulin, myoglobin and prolactin. The aim of this study was to evaluate the influence of dialysis duration and infusion flow (Qi) on the removal of different molecular weight (MW) solutes, and to quantify the effect of the different treatments on the kinetics of the solutes by using a classical two-compartment model. Methods: This prospective, in-center study was carried out in 10 patients on a nocturnal, every-other-day online post-dilution haemodiafiltration program. Each patient received four dialysis sessions with different conditions, two 4-h sessions (with infusion flows of 50 or 100 ml/min) and two 8-h sessions (with infusion flows of 50 or 100 ml/min). To analyze the solute kinetics, blood samples were obtained hourly during the dialysis treatments and in the first 3 h post-dialysis. Results: Removal patterns differed in the molecules studied, which were quantified by means of the two-compartment mathematical model. The main results show the impact of dialysis duration on the removal of low molecular weight molecules (urea and creatinine), while the impact of Qi is clearly shown for high molecular weight molecules (myoglobin and prolactin). For middle molecular weight solutes, such as β2-microglobulin, both factors (duration and Qi) enhance the removal efficiency of the dialyzer. Conclusions: Our study evaluates experimentally and mathematically how treatment time and infusion flow affect the filtration of solutes of different MW during post-dilution haemodiafiltration. The results provided by the present study should help physicians to select and individualise the most appropriate schedules to deliver an optimum diffusive and convective dialysis dose for each patient.

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Millisecond Kinetics of PbS Quantum Dots Using Droplet-based Microfluidics with On-line Absorption and Fluorescence Spectroscopy

MRS Proceedings ◽

10.1557/opl.2015.588 ◽

2015 ◽

Vol 1780 ◽

Author(s):

Ioannis Lignos ◽

Stavros Stavrakis ◽

Ardita Kilaj ◽

Andrew deMello

Keyword(s):

Quantum Dots ◽

Time Frame ◽

Quantitative Information ◽

Nucleation And Growth ◽

Microfluidic Platform ◽

Novel Approach ◽

Line Absorption ◽

On Line ◽

Pbs Quantum Dots ◽

Kinetics Of

ABSTRACTWe report a novel approach for the on-line characterization of nucleation and growth kinetics of lead sulfide (PbS) quantum dots using droplet-based microfluidics. Monodisperse NIR-emitting PbS with optical bandgap between 680 to 1200 nm can be formed rapidly using two reaction schemes at different operating temperatures between 70 and 130°C and the temporal evolution of the absorption and fluorescence spectra are monitored in real-time using a microfluidic platform with an on-line absorption and fluorescence optical system. Therefore, this microfluidic platform is able to provide quantitative information on a millisecond (ms) time frame regarding the size, size distribution, concentration and emission characteristics of the generated nuclei and particles. To our knowledge, this represents the first microfluidic approach for the study of the nucleation and growth in high-temperature colloidal crystallization using in-situ absorption and photoluminescence spectroscopy.

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