The prediction of fetal oxygenation by an on-line computer analysis of fetal monitor output

Abstract A computer program for the acquisition and on-line analysis of data from a high-resolution liquid chromatograph is described. Emphasis is placed on the means of designing the computer program to overcome certain problems encountered in analyzing the data, mainly as a result of noise. The areas discussed include: detection of the beginning and end of the peak, location of the peak maximum, calculation of peak area, location of inflection points, and resolution of overlapping peaks. Analytical results obtained from the computer analysis of reference compounds separated by highresolution liquid chromatography are presented. These results are compared with those obtained by manual quantitation of the chromatogram to illustrate the usefulness of the small, on-line computer as a quantitative tool in liquid chromatography.

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Analog signal processing of eye movements for on-line digital computer analysis

Physiology & Behavior ◽

10.1016/0031-9384(77)90109-3 ◽

1977 ◽

Vol 18 (1) ◽

pp. 157-158 ◽

Cited By ~ 2

Author(s):

Edward J. Engelken ◽

James W. Wolfe

Keyword(s):

Signal Processing ◽

Eye Movements ◽

Computer Analysis ◽

Digital Computer ◽

Analog Signal Processing ◽

Analog Signal ◽

On Line

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On-line computer analysis of chemiluminescent reactions, with application to a luminescent immunoassay for free cortisol in urine.

Clinical Chemistry ◽

10.1093/clinchem/30.10.1597 ◽

1984 ◽

Vol 30 (10) ◽

pp. 1597-1602 ◽

Cited By ~ 7

Author(s):

A Tommasi ◽

M Pazzagli ◽

M Damiani ◽

R Salerno ◽

G Messeri ◽

...

Keyword(s):

Computer Analysis ◽

Internal Control ◽

Biological Samples ◽

Light Emission ◽

Light Signal ◽

Simultaneous Evaluation ◽

Free Cortisol ◽

Shape Indices ◽

Chemiluminescent Reaction ◽

On Line

Abstract We interfaced a microcomputer on-line with a luminometer to acquire the light signal of chemiluminescent reactions from a photomultiplier and then compute significant parameters of light emission and kinetic "shape" indices. Using this system to study interferences from biological samples on the measurement of chemiluminescent reactions, we observed that such effects are usually associated with modifications of the shape of the light-emission kinetics. These results suggest that a simultaneous evaluation of the shape of a chemiluminescent reaction and the measurement of light emission can be combined to assess luminescent immunoassays as an internal control of the interferences in measurements of the chemiluminescent tracer. As an example of this approach, we developed and validated a luminescent immunoassay for free cortisol in diluted urine. Dextran-coated charcoal is used for bound-free separation.

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