A recombinant-based feline immunodeficiency virus antibody enzyme-linked immunosorbent assay

1992 ◽  
Vol 35 (1-2) ◽  
pp. 133-141 ◽  
Author(s):  
B. Mermer ◽  
P. Hillman ◽  
R. Harris ◽  
T. Krogmann ◽  
Q. Tonelli ◽  
...  
2005 ◽  
Vol 79 (3) ◽  
pp. 1954-1957 ◽  
Author(s):  
Margaret J. Hosie ◽  
Dieter Klein ◽  
James Μ. Binley ◽  
Thomas H. Dunsford ◽  
Oswald Jarrett ◽  
...  

ABSTRACT An inactivated virus vaccine was prepared from a pathogenic isolate of feline immunodeficiency virus containing a mutation that eliminated an endocytic sorting signal in the envelope glycoprotein, increasing its expression on virions. Cats immunized with inactivated preparations of this modified virus exhibited strong titers of antibody to Env by enzyme-linked immunosorbent assay. Evidence of protection following challenge demonstrated the potential of this approach to lentiviral vaccination.


2004 ◽  
Vol 40 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Bruce R. Madewell ◽  
Tracy L. Gieger ◽  
Patricia A. Pesavento ◽  
Michael S. Kent

Six cats developed malignant lymphoma 3 to 45 months after treatment for vaccine site-associated sarcoma. During the same time period, 184 cats were evaluated in the teaching hospital for vaccine site-associated sarcomas. Feline vaccine site-associated sarcoma is not believed to be associated with feline leukemia virus (FeLV) infection. Five of six cats were negative by enzyme-linked immunosorbent assay for FeLV antigens at the times of diagnosis of both sarcoma and lymphoma, and no cats were infected with feline immunodeficiency virus.


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