Three axis serial robots with different sizes are widely used for pick and place, welding and various operations in industry. Developments in mechatronics, which is the synergistic integration of mechanism, electronics and computer control to achieve a functional system, offer effective solutions for the design of such robots. The mechatronic design process involves solid modeling, assembly, rigid body dynamics, finite element rigidity analysis, motion control and computer programming. In this study, SolidWorks, CosmosMotion, CosmosWorks and PC-based motion control programs are used with an integrated approach. The integration software is developed in VisualBASIC by using the application programming interface (API) capabilities of these programs. An experimental three axis serial robot with a reach distance of 790 mm has been produced to develop and test the process.