Prostacyclin synthesis by the corpora cavernosa of the human penis: Evidence for muscarinic control and pathological implications

1986 ◽  
Vol 23 (2-3) ◽  
pp. 211-216 ◽  
Author(s):  
J.Y. Jeremy ◽  
R.J. Morgan ◽  
D.P. Mikhailidis ◽  
P. Dandona
Keyword(s):  
Corpora Cavernosa ◽  
Prostacyclin Synthesis

1071: Alterations of the Corpora Cavernosa Associated with Aging and Veno-Oclussive Dysfunction in the Rat

2005 ◽  
Vol 173 (4S) ◽  
pp. 290-291
Author(s):  
Hugo H. Davila ◽  
Rafael E. Carrion ◽  
Raoul Salup ◽  
Jacob Rajfer ◽  
Nestor F. Gonzalez-Cadavid
Keyword(s):  
Corpora Cavernosa

1448: Elastic System Fibers in the Corpora Cavernosa of Potent and Patients with Erectile Dysfunction

2004 ◽  
Vol 171 (4S) ◽  
pp. 381-381
Author(s):  
Waldemar S. Costa ◽  
Fabrício B. Carrerete ◽  
Ronaldo Damião ◽  
Marcia A. Babinski ◽  
Francisco J.B. Sampaio ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Elastic System ◽  
Corpora Cavernosa

Prostacyclin Synthesis Is Stimulated by a Serum Factor Formed During Coagulation

1983 ◽  
Vol 49 (01) ◽  
pp. 058-060 ◽  
Author(s):  
J M Ritter ◽  
M-A Ongari ◽  
M A Orchard ◽  
P J Lewis
Keyword(s):  
Renal Failure ◽  
Hydrolysis Product ◽  
Healthy Controls ◽  
Serum Factor ◽  
Intrinsic Pathway ◽  
Extrinsic Pathway ◽  
Stimulatory Activity ◽  
Plasma Factor ◽  
Stimulating Factor ◽  
Prostacyclin Synthesis

SummaryFresh aortic rings incubated in serum produce more 6-oxo-PGF1α, the stable hydrolysis product of prostacyclin, than in plasma or buffer. A method is described of recovering this stimulatory activity from a dialysate of serum, showing that the activity is due to a prostacyclin stimulating factor. This factor is formed during coagulation initiated by the intrinsic pathway but not by the extrinsic pathway or by thrombin. By contrast with a previously described plasma factor, the activity of the prostacy-clinstimulating factor in serum is not greater in serum from patients with renal failure than from healthy controls. The stimulating factor is antagonised by heparin, but differs in other ways from previously described platelet derived stimulating factor(s).

Effects of Aspirin and Sulfinpyrazone on Thromboxane and Prostacyclin Synthesis in Rabbits

1979 ◽  
Author(s):  
J McDonald ◽  
A Cerskus ◽  
M Ali
Keyword(s):  
Arachidonic Acid ◽  
Platelet Aggregation ◽  
Low Dose ◽  
High Dose ◽  
Prostacyclin Synthesis

Arachidonic acid (AA) or collagen were infused into rabbits causing intravascular platelet aggregation with thrombocytopenia, hypotension and death. Thromboxane and prostacyclin synthesis were measured by radioimmunoassay of plasma TXB2 and 6-keto-PGF1α. The effects of pretreatement with aspirin (ASA) or sulfinpyrazone(SPZ) were assessed.Death in drug-treated rabbits was always associated with elevations of plasma TXB2(1-40 ng/ml) and of 6-keto-PGF1α(1-20 ng/ml). Collagen produced only small elevations of plasma TXB2 compared to AA but protection by ASA correlated better with inhibition of TXB2 and 6-keto-PGF1α synthesis than with inhibition of aggregation. Low dose ASA produced less inhibition of prostacyclin synthesis than high dose ASA but was less effective in preventing thromboxane synthesis and death.

Penile Fracture-Report of Two Cases and Review of Current Literature

KYAMC Journal ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 122-125
Author(s):  
Ashraf Uddin Mallik ◽  
Mostafizur Rahman ◽  
Fatema Bagum ◽  
Uttam Karmaker ◽  
Baikali Ferdous ◽  
...  
Keyword(s):  
Tunica Albuginea ◽  
Traumatic Rupture ◽  
Penile Fracture ◽  
Corpora Cavernosa ◽  
Effective Treatment Modality ◽  
Special Cases ◽  
History Of ◽  
Penile Injury ◽  
Urological Emergency ◽  
Erect Penis

Penile fracture is an uncommon urological emergency, especially in Bangladesh. The other name is traumatic rupture of the tunica albuginea and corpora cavernosa in the erect penis. It occurs when an erect penis face to buckle under the pressure of a blunt sexual trauma. Patient gives the typical history of immediate detumescence, severe pain, swelling and eggplant deformity of the penile shaft due to penile injury. Immediate surgical exploration and repair of corpora Cavernosa with tunica albugenia is the most effective treatment modality. In normal cases diagnosis is made from history, physical examination alone. In some special cases ultrasonogram, radiological images, including retrograde urethrography or cavernosography are mandatory for proper diagnosis. KYAMC Journal Vol. 10, No.-2, July 2019, Page 122-125

scholarly journals The Combination of High-Fat Diet and Oral Marijuana Promotes the Development of Fibrosis in the Mouse Corpora Cavernosa

2021 ◽  
Vol 9 (2) ◽  
pp. 100312
Author(s):  
Sabine Nguyen ◽  
Michael Mangubat ◽  
Sriram Eleswarapu ◽  
Julian B. Wilson ◽  
Jocelyn Molina ◽  
...  
Keyword(s):  
High Fat Diet ◽  
High Fat ◽  
Corpora Cavernosa

Uretroplastica a lembo libero dorsale

1997 ◽  
Vol 64 (1_suppl) ◽  
pp. 127-128
Author(s):  
C. Bondavalli ◽  
C. Pegoraro ◽  
L. Schiavon ◽  
B. Dall'Oglio ◽  
M. Luciano ◽  
...  
Keyword(s):  
Skin Graft ◽  
Dorsal Approach ◽  
Corpora Cavernosa ◽  
Urethral Strictures ◽  
Free Skin Graft

The Authors report their experience in the new urethroplasty technique by Barbagli for penile and bulbar urethral strictures. This procedure involves a free skin graft sutured to the corpora cavernosa. With this dorsal approach mechanical weakening is virtually impossible, so pseudo-diverticulum or urethrocele cannot develop. We adopted this technique in 5 patients during the last 12 months. The strictures of the urethra were 2.5 to 8 cm long. The follow-up, even thought short, show that this technique is safe and quite simple.

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