Pulsed doppler techniques for measuring instantaneous maximum and mean flow velocities in carotid arteries

1984 ◽  
Vol 10 (4) ◽  
pp. 419-426 ◽  
Author(s):  
Karl-Fredrik Lindegaard ◽  
Søren Jacob Bakke ◽  
Arne Grip ◽  
Helge Nornes
Author(s):  
Srikant Venkatakrishnan ◽  
Meeka Khanna ◽  
Anupam Gupta

Abstract Background Transcranial color-coded duplex sonography (TCCD) provides information on intracranial blood flow status in stroke patients and can predict rehabilitation outcomes. Objective This study aimed to assess middle cerebral artery (MCA) parameters using TCCD in MCA territory stroke patients admitted for rehabilitation and correlate with clinical outcome measures. Material and Methods Patients aged 18 to 65 years with a first MCA territory stroke, within 6 months of onset were recruited. The clinical outcome scales and TCCD parameters were assessed at both admission and discharge. The scales used were the Scandinavian stroke scale (SSS), Barthel Index (BI), modified Rankin Scale (mRS), Fugl–Meyer upper extremity scale (FMA-UE), modified motor assessment scale (mMAS) scores. TCCD parameters measured were MCA peak systolic, end diastolic, mean flow velocities (MFV), and index of symmetry (SI) and were correlated with clinical scores. Results Fourteen patients were recruited with median age of 56.5 years, median duration of stroke was 42.5 days. Mean flow velocities of affected and unaffected MCA were 46.2 and 50.7 cm/s, respectively. Flow velocities and SI did not change between the two assessments. There was significant improvement in clinical outcome scores at discharge. Significant correlation was observed for patient group with SI > 0.9 at admission with FMA-UE, SSS, and BI scores at discharge (p < 0.05). Conclusion Flow velocity parameters did not change during in-patient rehabilitation. Patients with symmetric flow at admission had improved clinical outcomes measure scores at discharge. Thus SI can predict rehabilitation outcomes in stroke survivors.


Author(s):  
Dominik Wassmer ◽  
Bruno Schuermans ◽  
Christian Oliver Paschereit ◽  
Jonas P. Moeck

Lean premixed combustion promotes the occurrence of thermoacoustic phenomena in gas turbine combustors. One mechanism that contributes to the flame–acoustic interaction is entropy noise. Fluctuations of the equivalence ratio in the mixing section cause the generation of hot spots in the flame. These so-called entropy waves are convectively transported to the first stage of the turbine and generate acoustic waves that travel back to the flame; a thermoacoustic loop is closed. However, due to the lack of experimental tools, a detailed investigation of entropy waves in gas turbine combustion systems has not been possible up to now. This work presents an acoustic time-of-flight based temperature measurement method which allows the measurement of temperature fluctuations in the relevant frequency range. A narrow acoustic pulse is generated with an electric spark discharge close to the combustor wall. The acoustic response is measured at the same axial location with an array of microphones circumferentially distributed around the combustion chamber. The delay in the pulse arrival times corresponds to the line-integrated inverse speed of sound. For the measurement of entropy waves in an atmospheric combustion test rig, fuel is periodically injected into the mixing tube of a premixed combustor. The subsequently generated entropy waves are measured for different forcing frequencies of the fuel injection and for different mean flow velocities in the combustor. The amplitude decay and phase lag of the entropy waves adhere well to a Strouhal number scaling for different mean flow velocities.


2011 ◽  
Vol 91 (10) ◽  
pp. 1503-1512 ◽  
Author(s):  
Abigail Jade Hunter ◽  
Suzanne J. Snodgrass ◽  
Debbie Quain ◽  
Mark W. Parsons ◽  
Christopher R. Levi

BackgroundCerebral autoregulation can be impaired after ischemic stroke, with potential adverse effects on cerebral blood flow during early rehabilitation.ObjectiveThe objective of this study was to assess changes in cerebral blood flow velocity with orthostatic variation at 24 hours after stroke.DesignThis investigation was an observational study comparing mean flow velocities (MFVs) at 30, 15, and 0 degrees of elevation of the head of the bed (HOB).MethodsEight participants underwent bilateral middle cerebral artery (MCA) transcranial Doppler monitoring during orthostatic variation at 24 hours after ischemic stroke. Computed tomography angiography separated participants into recanalized (artery completely reopened) and incompletely recanalized groups. Friedman tests were used to determine MFVs at the various HOB angles. Mann-Whitney U tests were used to compare the change in MFV (from 30° to 0°) between groups and between hemispheres within groups.ResultsFor stroke-affected MCAs in the incompletely recanalized group, MFVs differed at the various HOB angles (30°: median MFV=51.5 cm/s, interquartile range [IQR]=33.0 to 103.8; 15°: median MFV=55.5 cm/s, IQR=34.0 to 117.5; 0°: median MFV=85.0 cm/s, IQR=58.8 to 127.0); there were no significant differences for other MCAs. For stroke-affected MCAs in the incompletely recanalized group, MFVs increased with a change in the HOB angle from 30 degrees to 0 degrees by a median of 26.0 cm/s (IQR=21.3 to 35.3); there were no significant changes in the recanalized group (−3.5 cm/s, IQR=−12.3 to 0.8). The changes in MFV with a change in the HOB angle from 30 degrees to 0 degrees differed between hemispheres in the incompletely recanalized group but not in the recanalized group.LimitationsGeneralizability was limited by sample size.ConclusionsThe incompletely recanalized group showed changes in MFVs at various HOB angles, suggesting that cerebral blood flow in this group may be sensitive to orthostatic variation, whereas the recanalized group maintained stable blood flow velocities.


Author(s):  
Dominik Wassmer ◽  
Bruno Schuermans ◽  
Christian Oliver Paschereit ◽  
Jonas P. Moeck

Lean premixed combustion promotes the occurrence of thermoacoustic phenomena in gas turbine combustors. One mechanism that contributes to the flame-acoustic interaction is entropy noise. Fluctuations of the equivalence ratio in the mixing section cause the generation of hot spots in the flame. These so called entropy waves are convectively transported to the first stage of the turbine and generate acoustic waves that travel back to the flame; a thermoacoustic loop is closed. However, due to the lack of experimental tools, a detailed investigation of entropy waves in gas turbine combustion systems has not been possible up to now. This work presents an acoustic time-of-flight based temperature measurement method which allows the detection of temperature fluctuations in the relevant frequency range. A narrow acoustic pulse is generated with an electric spark discharge close to the combustor wall. The acoustic response is measured at the same axial location with an array of microphones circumferentially distributed around the combustion chamber. The delay in the pulse arrival times corresponds to the line-integrated inverse speed of sound. For validation of this new method an experimental setup was developed capable of generating well defined entropy waves. As a reference temperature measurement technique a hot-wire anemometer is employed. For the measurement of entropy waves in an atmospheric combustion test rig, fuel is periodically injected into the mixing tube of a premixed combustor. The subsequently generated entropy waves are detected for different forcing frequencies of the fuel injection and for different mean flow velocities in the combustor. The amplitude decay and phase lag of the entropy waves adheres well to a Strouhal number scaling for different mean flow velocities. In addition, simultaneously to the entropy wave measurement, the equivalence ratio fluctuations in the mixing tube are detected using the Tunable Diode Laser Absorption Spectroscopy (TDLAS) technique.


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