Parametric multiecho proton spectroscopic imaging: Application to the rat brain in vivo

1995 ◽  
Vol 13 (5) ◽  
pp. 753-761 ◽  
Author(s):  
Wolfgang Dreher ◽  
Dieter Leibfritz
Biochemistry ◽  
2009 ◽  
Vol 48 (29) ◽  
pp. 6846-6853 ◽  
Author(s):  
Ingrid J. Pickering ◽  
Eileen Yu Sneeden ◽  
Roger C. Prince ◽  
Eric Block ◽  
Hugh H. Harris ◽  
...  

2006 ◽  
Vol 24 (5) ◽  
pp. 549-555 ◽  
Author(s):  
Matthias Althaus ◽  
Wolfgang Dreher ◽  
Christian Geppert ◽  
Dieter Leibfritz

Author(s):  
D.J. Meyerhoff

Magnetic Resonance Imaging (MRI) observes tissue water in the presence of a magnetic field gradient to study morphological changes such as tissue volume loss and signal hyperintensities in human disease. These changes are mostly non-specific and do not appear to be correlated with the range of severity of a certain disease. In contrast, Magnetic Resonance Spectroscopy (MRS), which measures many different chemicals and tissue metabolites in the millimolar concentration range in the absence of a magnetic field gradient, has been shown to reveal characteristic metabolite patterns which are often correlated with the severity of a disease. In-vivo MRS studies are performed on widely available MRI scanners without any “sample preparation” or invasive procedures and are therefore widely used in clinical research. Hydrogen (H) MRS and MR Spectroscopic Imaging (MRSI, conceptionally a combination of MRI and MRS) measure N-acetylaspartate (a putative marker of neurons), creatine-containing metabolites (involved in energy processes in the cell), choline-containing metabolites (involved in membrane metabolism and, possibly, inflammatory processes),


2001 ◽  
Vol 120 (5) ◽  
pp. A116-A116
Author(s):  
H SCHLEMMER ◽  
T SAWATZKI ◽  
I DORNACHER ◽  
S SAMMET ◽  
M HELLENSCHMIDT ◽  
...  

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S468-S468
Author(s):  
Jennifer K Callaway ◽  
Christine Molnar ◽  
Song T Yao ◽  
Bevyn Jarrott ◽  
R David Andrew

2013 ◽  
Vol 44 (S 01) ◽  
Author(s):  
M Breu ◽  
D Reisinger ◽  
D Wu ◽  
Y Zhang ◽  
A Fatemi ◽  
...  

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