Clinical Translation of Cartilage Tissue Engineering, From Embryonic Development to a Promising Long-Term Solution

Author(s):  
Diego Correa ◽  
Annie C. Bowles
Author(s):  
C. C. van Donkelaar ◽  
M. Khoshgoftar ◽  
L. M. Kock ◽  
K. Ito

Tissue engineered cartilage has reached the level of maturity where the cells, either chondrocytes, BMSC’s or other cells are stimulated to produce a tissue of which the biochemical content qualitatively resembles that of native cartilage. Quantitatively, the proteoglycan content approaches that of native content in long term cultures, but to obtain native collagen fractions is still challenging. Engineered cartilage matrix is either homogeneously distributed, or shows gradual variation from the periphery to the center, caused by nutritional effects.


2017 ◽  
Vol 36 (6) ◽  
pp. 1717-1727 ◽  
Author(s):  
Minwook Kim ◽  
Sean T. Garrity ◽  
David R. Steinberg ◽  
George R. Dodge ◽  
Robert L. Mauck

2010 ◽  
Vol 18 ◽  
pp. S84
Author(s):  
J. Schiavi-Tritz ◽  
N. Charif ◽  
N. de Isla ◽  
R. Rahouadj ◽  
A. Pinzano ◽  
...  

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