Recent developments on ionic liquids-mediated synthetic protocols for biologically relevant five- and six-membered heterocyclic skeletons

2021 ◽  
pp. 301-364
Author(s):  
Priyanka Bose ◽  
Anand K. Agrahari ◽  
Sumit K. Singh ◽  
Anoop S. Singh ◽  
Mangal S. Yadav ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Biologically Relevant ◽  
Recent Developments

scholarly journals Block copolymer self-assembly in ionic liquids

2018 ◽  
Vol 20 (39) ◽  
pp. 25123-25139 ◽  
Author(s):  
Ryota Tamate ◽  
Kei Hashimoto ◽  
Takeshi Ueki ◽  
Masayoshi Watanabe
Keyword(s):  
Ionic Liquids ◽  
Block Copolymer ◽  
Self Assembly ◽  
Recent Developments

Recent developments in block copolymer self-assembly in ionic liquids are reviewed from both fundamental and applied aspects.

Ion transport in polymeric ionic liquids: recent developments and open questions

2019 ◽  
Vol 4 (2) ◽  
pp. 280-293 ◽  
Author(s):  
Venkat Ganesan
Keyword(s):  
Ionic Liquids ◽  
Ion Transport ◽  
Charge Transport ◽  
Transport Mechanisms ◽  
Polymeric Ionic Liquids ◽  
Open Questions ◽  
Recent Developments

Recent developments and outstanding questions in the context of charge transport mechanisms in polymeric ionic liquids are highlighted.

An initial characterization of the proteolytic enzymes secreted by the adult stage of the human hookworm Necator americanus

Parasitology ◽  
1995 ◽  
Vol 110 (5) ◽  
pp. 555-563 ◽  
Author(s):  
A. Brown ◽  
J. M. Burleigh ◽  
E. E. Billett ◽  
D. I. Pritchard
Keyword(s):  
Serine Proteases ◽  
Metal Ion ◽  
Proteolytic Enzymes ◽  
Maximum Activity ◽  
Biologically Relevant ◽  
Necator Americanus ◽  
Recent Developments ◽  
Proteolytic Activities ◽  
Secretory Products ◽  
Ph Range

SUMMARYThe proteolytic activities present in adult Necator americanus excretory–secretory products have been assessed using biologically relevant, naturally occurring substrates (haemoglobin and fibrinogen) and a number of synthetic fluorogenic and chromogenic substrates. One broad peak of activity was observed against haemoglobin in the pH range 5 to 7, with maximum activity at pH 6·6, while fibrinogenolytic activity was shown to be greater at pH 3·5. Inhibition studies against haemoglobin, fibrinogen and synthetic substrates using a battery of appropriate protease inhibitors indicated the presence of a mixture of aspartyl, cysteinyl and serine proteases. Metal ion (Ca2+, Zn2+ and Fe2+) stimulation was demonstrated, with stimulation by Zn2+ being the most marked. These results are discussed in the context of recent developments in the field of parasite proteolytic enzymes, where they have been suggested as targets for immuno- and chemotherapy.

scholarly journals Recent Developments on 1,3-Dipolar Cycloaddition Reactions by Catalysis in Green Solvents

Catalysts ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 65 ◽  
Author(s):  
Loredana Maiuolo ◽  
Vincenzo Algieri ◽  
Fabrizio Olivito ◽  
Antonio De Nino
Keyword(s):  
Ionic Liquids ◽  
Heterocyclic Compounds ◽  
Deep Eutectic Solvents ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Important Class ◽  
Green Solvents ◽  
Dipolar Cycloadditions ◽  
Recent Developments ◽  
Selection Of

The use of eco-compatible synthetic procedures in organic reactions and, in particular, in 1,3-dipolar cycloaddition reactions, has recently received a great deal of attention and considerable progress has been achieved in this area in the last years. This review summarizes the approaches currently employed to synthesize heterocyclic compounds by catalyzed 1,3-dipolar cycloadditions in green solvents in the last six years. Our choice to do a selection of the literature from 2014 to 2019 was made considering the absence of a recent review about this period, to our knowledge. Several examples to construct heterocycles by 1,3-dipolar cycloadditions will be discussed in this work subdivided in function of the most important class of non-conventional and green solvents, i.e., ionic liquids (ILs), deep eutectic solvents (DES), and water.

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