Malignant diseases of the uterus

2022 ◽  
pp. 691-706.e5
Author(s):  
Pamela T. Soliman ◽  
Karen H. Lu
Keyword(s):  
2013 ◽  
Vol 19 (30) ◽  
pp. 5429-5436 ◽  
Author(s):  
Manal Amoury ◽  
Tobias Blume ◽  
Hannes Brehm ◽  
Judith Niesen ◽  
Niklas Tenhaef ◽  
...  
Keyword(s):  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ali H. Baykan ◽  
Hakan S. Sayiner ◽  
Ibrahim Inan ◽  
Elcin Aydin ◽  
Sukru M. Erturk

AbstractBreast tuberculosis is a rare form of extrapulmonary tuberculosis which tends to affect females of reproductive age, and is much rarer in males, postmenopausal women, and pre-pubescent girls. It is difficult to diagnose because it can mimic benign conditions such as a fibroadenoma, as well as malignant diseases like a carcinoma. It is also particularly difficult to distinguish breast tuberculosis from granulomatous mastitis, so other possible diagnoses should be ruled out first. The diagnosis of breast tuberculosis has three essential pillars: clinical examination, radiological evaluations, and histopathological sampling. Radiological evaluations are not only critical in diagnosis but are also important in the planning of the treatment and during the follow-up. This paper aims to review the imaging findings and the differential diagnosis of breast tuberculosis.


Author(s):  
Nina Zila ◽  
Christoph Hoeller ◽  
Verena Paulitschke

SummaryIn malignant diseases, targeting of immune checkpoints successfully changed the therapeutic landscape and helped to unleash anti-tumor T cell responses, resulting in durable clinical outcomes, but only in up to 50% of patients. The success of these therapies and the need to overcome intrinsic and acquired therapy resistance stimulated research to identify new pathways and targets. Numerous clinical trials are currently evaluating novel checkpoint inhibitors or recently developed strategies like modulating the tumor microenvironment, mostly in combination with approved therapies. This short review briefly discusses promising therapeutic targets, currently still under investigation, with the chance to realize clinical application in the foreseeable future.


2014 ◽  
Vol 69 (12) ◽  
pp. 1295-1303 ◽  
Author(s):  
A. Neelakantan ◽  
A.K. Rana
Keyword(s):  

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