Cell Fate Determination and Signal Transduction during Caenorhabditis elegans Vulval Development

1999 ◽  
pp. 157-170
Author(s):  
Alex Hajnal
Keyword(s):  
Signal Transduction ◽  
Caenorhabditis Elegans ◽  
Cell Fate ◽  
Cell Fate Determination ◽  
Vulval Development ◽  
Fate Determination

scholarly journals Two Murine and Human Homologs of Mab-21, a Cell Fate Determination Gene Involved in Caenorhabditis Elegans Neural Development

1999 ◽  
Vol 8 (13) ◽  
pp. 2397-2406 ◽  
Author(s):  
M. Mariani ◽  
D. Baldessari ◽  
S. Francisconi ◽  
L. Viggiano ◽  
M. Rocchi ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Cell Fate ◽  
Neural Development ◽  
Cell Fate Determination ◽  
Fate Determination ◽  
A Cell

Reversal of cell fate determination in Caenorhabditis elegans vulval development

Development ◽  
1996 ◽  
Vol 122 (8) ◽  
pp. 2507-2515 ◽  
Author(s):  
S. Euling ◽  
V. Ambros
Keyword(s):  
Caenorhabditis Elegans ◽  
Cell Fate ◽  
Larval Stage ◽  
Cell Types ◽  
Wild Type ◽  
Vulval Development ◽  
Fate Determination ◽  
Developmental Arrest ◽  
Dauer Larva ◽  
Vulval Precursor Cells

In Caenorhabditis elegans, the fates of the multipotent vulval precursor cells (VPCs) are specified by intercellular signals. The VPCs divide in the third larval stage (L3) of the wild type, producing progeny of determined cell types. In lin-28 mutants, vulva development is similar to wild-type vulva development except that it occurs precociously, in the second larval stage (L2). Consequently, when lin-28 hermaphrodites temporarily arrest development at the end of L2 in the dauer larva stage, they have partially developed vulvae consisting of VPC progeny. During post-dauer development, these otherwise determined VPC progeny become reprogrammed back to the multipotent, signal-sensitive state of VPCs. Our results indicate that VPC fate determination by intercellular signals is reversible by dauer larva developmental arrest and post-dauer development.

scholarly journals The LIN-15A and LIN-56 Transcriptional Regulators Interact to Negatively Regulate EGF/Ras Signaling in Caenorhabditis elegans Vulval Cell-Fate Determination

Genetics ◽  
2010 ◽  
Vol 187 (3) ◽  
pp. 803-815 ◽  
Author(s):  
Ewa M. Davison ◽  
Adam M. Saffer ◽  
Linda S. Huang ◽  
John DeModena ◽  
Paul W. Sternberg ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Cell Fate ◽  
Transcriptional Regulators ◽  
Ras Signaling ◽  
Cell Fate Determination ◽  
Fate Determination
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