Development of a rapid method for the analysis of synthetic growth promoters in bovine muscle using liquid chromatography tandem mass spectrometry

2009 ◽  
Vol 637 (1-2) ◽  
pp. 112-120 ◽  
Author(s):  
E.M. Malone ◽  
C.T. Elliott ◽  
D.G. Kennedy ◽  
L. Regan
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Rapid Method ◽  
Tandem Mass ◽  
Growth Promoters ◽  
Bovine Muscle ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Synthetic Growth

scholarly journals Quantitative LC/MS-MS Determination of Sulfonamides and Some Other Antibiotics in Honey

2002 ◽  
Vol 85 (4) ◽  
pp. 853-860 ◽  
Author(s):  
Anton Kaufmann ◽  
Sven Roth ◽  
Bianca Ryser ◽  
Mirjam Widmer ◽  
Dominik Guggisberg
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Rapid Method ◽  
Limit Of Detection ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

Abstract A simple and rapid method was developed for the determination of 20 antibiotics (sulfonamides, tetracyclines, and flumequine) in honey by liquid chromatography tandem mass spectrometry. The proposed method is sensitive (limit of detection 0.5 to 10 ppb for the various antibiotics) and selective. A hydrolysis step ensures the liberation of sugar-bound sulfonamides. The approach has been used to analyze some 300 honey samples. A number of them were found to have exceeded the Swiss limit of 50 ppb.

scholarly journals Determination of Four Nitroimidazoles in Poultry and Swine Muscle and Eggs by Liquid Chromatography/Tandem Mass Spectrometry

2006 ◽  
Vol 89 (1) ◽  
pp. 94-99 ◽  
Author(s):  
Xi Xia ◽  
Xiaowei Li ◽  
Jianzhong Shen ◽  
Suxia Zhang ◽  
Shuangyang Ding ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Rapid Method ◽  
Organic Phase ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Detection Capabilities

Abstract A rapid method is presented for the determination of 4 nitroimidazoles in poultry and swine muscle and eggs by liquid chromatographyelectrospray ionizationtandem mass spectrometry (LCESIMSMS). Samples were extracted with acetonitrile, then evaporated the organic phase. After filtration, the extract was directly injected into the LCESIMSMS system. The LC separation was made on a C8 column by applying a gradient composed of water and acetonitrile. Overall average recoveries ranged from 5086 for egg, 66115 for poultry muscle, and 79111 for swine muscle. The decision limits ranged from 0.05-0.25 μgkg for egg, 0.07-0.27 μgkg for poultry muscle, and 0.07-0.26 μgkg for swine muscle; and detection capabilities ranged from 0.510.68 gkg for egg, 0.41-0.75 μgkg for poultry muscle, and 0.53-0.78 μgkg for swine muscle.

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