Quantifying silver nanoparticle association and elemental content in single cells using dual mass mode in quadrupole-based inductively coupled plasma-mass spectrometry

2019 ◽  
Vol 1061 ◽  
pp. 50-59 ◽  
Author(s):  
Judy Tsz-Shan Lum ◽  
Kelvin Sze-Yin Leung
Keyword(s):  
Mass Spectrometry ◽  
Silver Nanoparticle ◽  
Inductively Coupled Plasma ◽  
Single Cells ◽  
Elemental Content ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

A simple metal staining procedure for identification and visualization of single cells by LA-ICP-MS

The Analyst ◽  
2017 ◽  
Vol 142 (10) ◽  
pp. 1703-1710 ◽  
Author(s):  
A. J. Herrmann ◽  
S. Techritz ◽  
N. Jakubowski ◽  
A. Haase ◽  
A. Luch ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Single Cells ◽  
Staining Procedure ◽  
Simple Metal ◽  
Inductively Coupled ◽  
Icp Ms ◽  
High Lateral Resolution ◽  
Plasma Mass Spectrometry ◽  
Staining Methods

High lateral resolution of metal detection in single cells by use of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) demands powerful staining methods.

scholarly journals Quantification of silver nanoparticles taken up by single cells using inductively coupled plasma mass spectrometry in the single cell measurement mode

2018 ◽  
Vol 33 (7) ◽  
pp. 1256-1263 ◽  
Author(s):  
Ana López-Serrano Oliver ◽  
Sabine Baumgart ◽  
Wolfram Bremser ◽  
Sabine Flemig ◽  
Doreen Wittke ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Silver Nanoparticles ◽  
Cell Surface ◽  
Inductively Coupled Plasma ◽  
Single Cells ◽  
Analytical Methodology ◽  
Inductively Coupled ◽  
Cell Measurement ◽  
Measurement Mode ◽  
Plasma Mass Spectrometry

A promising analytical methodology is proposed to study nanoparticle-cell interactions providing information of the number of NPs internalized by cells or externally bound to the cell surface.

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