scholarly journals Global longitudinal strain by speckle-tracking echocardiography and feature-tracking cardiac magnetic resonance predicting left and right ventricular performance after mitral regurgitation repair

2020 ◽  
Vol 12 (2-4) ◽  
pp. 252
Author(s):  
K. Hami ◽  
S. Lazam ◽  
S. Militaru ◽  
S. Lejeune ◽  
B. Gerber
2020 ◽  
Vol 14 (11) ◽  
pp. e0008795
Author(s):  
Minna Moreira Dias Romano ◽  
Henrique Turin Moreira ◽  
José Antônio Marin-Neto ◽  
Priscila Elias Baccelli ◽  
Fawaz Alenezi ◽  
...  

Chagas disease (CD) will account for 200,000 cardiovascular deaths worldwide over the next 5 years. Early detection of chronic Chagas cardiomyopathy (CCC) is a challenge. We aimed to test if speckle-tracking echocardiography (STE) can detect incipient myocardial damage in CD. METHODS: Among 325 individuals with positive serological tests, 25 (age 55±12yrs) were selected to compose the group with indeterminate form of Chagas disease (IFCD), based on stringent criteria of being asymptomatic and with normal EKG/X-ray studies. This group was compared with a group of 20 patients with CCC (55±11yrs) and a group of 20 non-infected matched control (NC) subjects (48±10yrs). CD patients and NC were submitted to STE and CD patients were submitted to cardiac magnetic resonance (CMR) with late gadolinium administration to detect cardiac fibrosis by the late enhancement technique. Global longitudinal strain (GLS), circumferential (GCS) and radial strain (GRS) were defined as the average of segments measured from three apical view (GLS) and short axis views (GRS and GCS). Regional left ventricular (LV) longitudinal strain (Reg LS) was measured from each of the 17 segments. Twist was measured as systolic peak difference between basal and apical rotation and indexed to LV length to express torsion. RESULTS: STE global indices (GLS, GCS, twist and torsion) were reduced in CCC vs NC (GLS: -14±6.3% vs -19.3±1.6%, p = 0.001; GCS: -13.6±5.2% vs -17.3 ±2.8%; p = 0.008; twist: 8±7° vs 14±7°, p = 0.01 and torsion: 0.96±1°/cm vs 1.9±1°/cm, p = 0.005), but showed no differences in IFCD vs NC. RegLS was reduced in IFCD vs NC in four LV segments: basal-inferior (-16.3±3.3% vs -18.6±2.2%, p = 0.013), basal inferoseptal (-13.1±3.4 vs -15.2±2.7, p = 0.019), mid-inferoseptal (-17.7±3.2 vs -19.4±2, p = 0.032) and mid-inferolateral (-15.2±3.5 vs -17.8±2.8, p = 0.014). These abnormalities in RegLS occurred in the absence of myocardial fibrosis detectable with CMR in nearly 92% of subjects with IFCD, while myocardial fibrosis was present in 65% with CCC. CONCLUSION: RegLS detects early regional impairment of myocardial strain that is independent from fibrosis in IFCD subjects.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Saikrishna Ananthapadmanabhan ◽  
Giau Vo ◽  
Tuan Nguyen ◽  
Hany Dimitri ◽  
James Otton

Abstract Background Cardiac magnetic resonance feature tracking (CMR-FT) and speckle tracking echocardiography (STE) are well-established strain imaging modalities. Multilayer strain measurement permits independent assessment of endocardial and epicardial strain. This novel and layer specific approach to evaluating myocardial deformation parameters may provide greater insight into cardiac contractility when compared to whole-layer strain analysis. The aim of this study is to validate CMR-FT as a tool for multilayer strain analysis by providing a direct comparison between multilayer global longitudinal strain (GLS) values between CMR-FT and STE. Methods We studied 100 patients who had an acute myocardial infarction (AMI), who underwent CMR imaging and echocardiogram at baseline and follow-up (48 ± 13 days). Dedicated tissue tracking software was used to analyse single- and multi-layer GLS values for CMR-FT and STE. Results Correlation coefficients for CMR-FT and STE were 0.685, 0.687, and 0.660 for endocardial, epicardial, and whole-layer GLS respectively (all p < 0.001). Bland Altman analysis showed good inter-modality agreement with minimal bias. The absolute limits of agreement in our study were 6.4, 5.9, and 5.5 for endocardial, whole-layer, and epicardial GLS respectively. Absolute biases were 1.79, 0.80, and 0.98 respectively. Intraclass correlation coefficient (ICC) values showed moderate agreement with values of 0.626, 0.632, and 0.671 respectively (all p < 0.001). Conclusion There is good inter-modality agreement between CMR-FT and STE for whole-layer, endocardial, and epicardial GLS, and although values should not be used interchangeably our study demonstrates that CMR-FT is a viable imaging modality for multilayer strain


Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Celine Goffinet ◽  
Patrick Montant ◽  
Fabien Chenot ◽  
David Vancraeynest ◽  
Agnes Pasquet ◽  
...  

Background. Speckle tracking echocardiography (STE) is a new method that allows to quantitalively measure myocardial deformation in an angle-independent manner. The aim of this study was to evaluate the accuracy of STE-derived estimates of circumferential and longitudinal strains, in patients with variable degrees of LV dysfunction, using tagged cardiac magnetic resonance (cMR) as the reference standard. Methods. A total of 80 patients (66 men, mean age 54 ± 16 years) with a variety of cardiac diseases underwent STE and cMR on the same day. For circumferential strain, data were analyzed on matched short-axis cross-sections (at basal and apical levels) using either the QLab software (for STE) or HARP (for tagged cMR). For longitudinal strain, data were analyzed on similar 4-, 3- and 2-chamber views using either QLab (for STE) or a custom-made program that allows for tracking of cMR tags in long-axis projections (for tagged cMR). Results. 87% of myocardial segments could be analyzed. Correlation and limits of agreement between STE and cMR were good for both global (r = 0.95, p<0.001 and 1.2 ± 5.1%, respectively) and segmental circumferential strain (r=0.84, p<0.001 and 1.1 ± 9.9%, respectively, figure1 ). Correlation and limits of agreement between STE and cMR were similarly good for global (r =0.96, p<0.001 and −0.1 ± 3.0%, respectively) and segmental longitudinal strain (r = 0.77, p<0.001 and 0.2 ± 9.6%, respectively, figure1 ). Conclusions. STE provides accurate measurements of segmental circumferential and longitudinal strains and thus offers the opportunity to routinely assess these parameters in daily clinical practice.


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