The effects of nicotine on conditioning, extinction, and reinstatement in humans

2018 ◽  
Vol 77 ◽  
pp. 51-58 ◽  
Author(s):  
Alexandra N. Palmisano ◽  
Eleanor C. Hudd ◽  
Courtney M. McQuade ◽  
Harriet de Wit ◽  
Robert S. Astur
1964 ◽  
Vol 15 (1) ◽  
pp. 259-275 ◽  
Author(s):  
Victor J. Cieutat

Two studies concerned effects of sex of Ss, sex of E, positive vs negative reinforcement (i.e., attention vs inattention), and time trends, on the conditioning and extinction of participation in structured and unstructured small group discussions. Previous results indicated reinforcement is effective only when administered by an E of the same sex as Ss. Present results did not support this expectation and also were not consistent with each other. Exp. I was partly consistent with expectation only when E was male; no conditioning was obtained by female Es. For Exp. II only the female E produced conditioning. Extinction effects in both experiments were inconsistent with expectation. In an earlier study (Cieutat, 1962) and in both Exps. I and II the same four factors were evaluated with some design modification, and were found to interact complexly and significantly ( p < .01, < .10, < .10, respectively). These interactions between sex of E, sex of Ss, reinforcement, and time, though significant in three independent evaluations, were so because of different trends in each case. These differences are discussed in terms of uncontrolled personality differences between Es and Ss.


2010 ◽  
Vol 203 (2) ◽  
pp. 285-297 ◽  
Author(s):  
Erin L. Zelinski ◽  
Nancy S. Hong ◽  
Amanda V. Tyndall ◽  
Brett Halsall ◽  
Robert J. McDonald

1964 ◽  
Vol 15 (3) ◽  
pp. 883-887 ◽  
Author(s):  
John M. Vacher ◽  
James N. Shafer

Forty-eight rats were tested in conditioning, extinction and spontaneous recovery with levels of response-produced light or no light across the factors. The results indicated that response-produced light is rewarding as a function of its novelty when presented during the test for spontaneous recovery. Light presented in extinction depressed responding in recovery, an effect which was inhibited when light was presented during conditioning.


1998 ◽  
Vol 4 (2) ◽  
pp. 122-132 ◽  
Author(s):  
Dennis S. Charney ◽  
Christian C. G. Grillon ◽  
J. Douglas Bremner

This article is Part II of a review of the neuronal circuits, neural mechanisms, and neuromodulators that seem to be involved in anxiety and fear states. Part I focused on the specific brain structures, including the roles of the amygdala, locus coeruleus, hippocampus, and various cortical regions and the neural mechanisms of fear conditioning, extinction, and behavioral sensitization in mediating the signs and symptoms of anxiety and fear. Part II attempts to develop a better understanding of neurochemical mediation of traumatic remembrance and the neurobiological consequences of stress, particularly when experienced early in life. Finally, the data is synthesized to provide a basis for understanding the pathophysiology of anxiety disorders, such as Panic disorder and Posttraumatic Stress Disorder. NEUROSCIENTIST 4:122–132, 1998


2015 ◽  
Vol 57 (7) ◽  
pp. 818-832 ◽  
Author(s):  
Miriam Liora Den ◽  
Bronwyn M. Graham ◽  
Carol Newall ◽  
Rick Richardson

2008 ◽  
Vol 28 (12) ◽  
pp. 571-574 ◽  
Author(s):  
Raquel Ribeiro Barbosa ◽  
Idalécio Pacífico da Silva ◽  
Benito Soto-Blanco

The aim of this study was to determine whether goats could be averted from consuming Mascagnia rigida, a toxic plant found in the semiarid region of northeastern Brazil. Fourteen male goats not previously familiarized to M. rigida were randomly allocated to two treatment groups: control (treated with 5.5mL water orally by a drenching gun) and lithium group (treated with 100mg LiCl/kg body weight orally by a drenching gun). For conditioning, goats were allowed to feed on M. rigida leaves for 15 min, followed by LiCl or water administration. The time spent on eating M. rigida leaves was measured. The conditioning was repeated daily until the LiCl-treated goats stopped eating M. rigida. On the 10th, 17th, and 24th day after conditioning, extinction trials of the M. rigida aversion were performed in goats by using single-choice tests. There was no difference between the two treatment groups with respect to the consumption of M. rigida on the first day of aversion conditioning, however, controls ingested increasing amounts of the plant on consecutive conditioning days. On the second day, five out of the seven goats in the lithium group did not eat the leaves, but on the third day, all the goats in the lithium group did not ingest M. rigida. This aversion persisted throughout all evaluated days. This indicates that goats can be easily conditioned by using lithium chloride to avoid eating M. rigida temporarily.


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