scholarly journals Modeling alcohol use disorder as a set of interconnected symptoms – Assessing differences between clinical and population samples and across external factors

2022 ◽  
Vol 125 ◽  
pp. 107128
Author(s):  
K.B.S. Huth ◽  
J. Luigjes ◽  
M. Marsman ◽  
A.E. Goudriaan ◽  
R.J. van Holst
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
External Factors

scholarly journals Modeling Alcohol Use Disorder as a Set of Interconnected Symptoms - Assessing Differences between Clinical and Population Samples and Across External Factors

2021 ◽  
Author(s):  
Karoline Huth ◽  
Judy Luigjes ◽  
Maarten Marsman ◽  
Anneke Goudriaan ◽  
Ruth van Holst
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Clinical Sample ◽  
Population Sample ◽  
External Factors ◽  
Underlying Structure ◽  
Parameter Estimates ◽  
Complex Disorder ◽  
Theoretical Assumptions ◽  
Intervention Planning

Alcohol use disorder is argued to be a highly complex disorder influenced by a multitude of factors on different levels. Common research approaches fail to capture this breadth of interconnecting symptoms. To address this gap in theoretical assumptions and methodological approaches, we used a network analysis to assess the interplay of alcohol use disorder symptoms. We applied the analysis to two US-datasets, a population sample with 23,591 individuals and a clinical sample with 483 individuals seeking treatment for alcohol use disorder. First, using a Bayesian framework we investigated differences between clinical and population samples looking at the symptom interactions and underlying structure space. The clinical sample depicts less connections; those connections are additionally weaker. Second, for the population sample we assessed whether the interactions were measurement invariant across subgroups of external factors like age, gender, ethnicity and income. Interactions differed across all external factors. Distinct parameter estimates for subgroups should be considered for better replicable estimates and effective intervention planning.

DSM-5 alcohol use disorder features among treatment-seeking older adults

2018 ◽  
Vol 64 (4) ◽  
pp. 185-196 ◽  
Author(s):  
Silke Behrendt ◽  
Barbara Braun ◽  
Randi Bilberg ◽  
Gerhard Bühringer ◽  
Michael Bogenschutz ◽  
...  
Keyword(s):  
Older Adults ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
The Elderly ◽  
Treatment Seeking ◽  
Controlled Clinical Trial ◽  
Dsm 5 ◽  
Wide Range ◽  
And Gender ◽  
International Multicenter

Abstract. Background: The number of older adults with alcohol use disorder (AUD) is expected to rise. Adapted treatments for this group are lacking and information on AUD features in treatment seeking older adults is scarce. The international multicenter randomized-controlled clinical trial “ELDERLY-Study” with few exclusion criteria was conducted to investigate two outpatient AUD-treatments for adults aged 60+ with DSM-5 AUD. Aims: To add to 1) basic methodological information on the ELDERLY-Study by providing information on AUD features in ELDERLY-participants taking into account country and gender, and 2) knowledge on AUD features in older adults seeking outpatient treatment. Methods: baseline data from the German and Danish ELDERLY-sites (n=544) were used. AUD diagnoses were obtained with the Mini International Neuropsychiatric Interview, alcohol use information with Form 90. Results: Lost control, desired control, mental/physical problem, and craving were the most prevalent (> 70 %) AUD-symptoms. 54.9 % reported severe DSM-5 AUD (moderate: 28.2 %, mild: 16.9 %). Mean daily alcohol use was 6.3 drinks at 12 grams ethanol each. 93.9 % reported binging. More intense alcohol use was associated with greater AUD-severity and male gender. Country effects showed for alcohol use and AUD-severity. Conclusion: European ELDERLY-participants presented typical dependence symptoms, a wide range of severity, and intense alcohol use. This may underline the clinical significance of AUD in treatment-seeking seniors.

Persönliche vs. computerbasierte Alkoholintervention für Krankenhauspatienten: Studiendesign

2015 ◽  
Vol 61 (6) ◽  
pp. 347-355 ◽  
Author(s):  
Jennis Freyer-Adam ◽  
Sophie Baumann ◽  
Inga Schnuerer ◽  
Katja Haberecht ◽  
Ulrich John ◽  
...  
Keyword(s):  
Public Health ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Identification Test ◽  
Disorder Identification

Zusammenfassung. Ziel: Persönliche Beratungen können bei stationären Krankenhauspatienten Alkoholkonsum und Mortalität reduzieren. Sie sind jedoch mit hohen Kosten verbunden, wenn aus Public-Health-Erfordernis viele Menschen einer Bevölkerung erreicht werden müssen. Computerbasierte Interventionen stellen eine Alternative dar. Jedoch ist ihre Wirksamkeit im Vergleich zu persönlichen Beratungen und im Allgemeinkrankenhaus noch unklar. Eine quasi-randomisierte Kontrollgruppenstudie „Die Bedeutung der Vermittlungsform für Alkoholinterventionen bei Allgemeinkrankenhauspatienten: Persönlich vs. Computerisiert“ soll dies untersuchen. Design und Methoden werden beschrieben. Methode: Über 18 Monate sind alle 18- bis 64-jährigen Patienten auf Stationen der Universitätsmedizin Greifswald mittels Alcohol Use Disorder Identification Test (AUDIT) zu screenen. Frauen/Männer mit AUDIT-Consumption ≥ 4/5 und AUDIT < 20 werden einer von drei Gruppen zugeordnet: persönliche Intervention (Beratungen zur Konsumreduktion), computerbasierte Intervention (individualisierte Rückmeldebriefe und Broschüren) und Kontrollgruppe. Beide Interventionen erfolgen im Krankenhaus sowie telefonisch bzw. postalisch nach 1 und 3 Monaten. In computergestützten Telefoninterviews nach 6, 12, 18 und 24 Monaten wird Alkoholkonsum erfragt. Schlussfolgerung: Das Studienvorhaben, sofern erfolgreich umgesetzt, ist geeignet die längerfristige Wirksamkeit einer persönlichen und computerbasierten Intervention im Vergleich zu untersuchen.

Does exposure exacerbate symptoms in veterans with PTSD and alcohol use disorder?

2020 ◽  
Author(s):  
Jessica C. Tripp ◽  
Moira Haller ◽  
Ryan S. Trim ◽  
Elizabeth Straus ◽  
Craig J. Bryan ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder

Animal models of alcohol use disorder and the brain: From casual drinking to dependence.

2019 ◽  
Vol 5 (3) ◽  
pp. 222-242 ◽  
Author(s):  
Nicole A. Crowley ◽  
Nigel C. Dao ◽  
Sarah N. Magee ◽  
Alexandre J. Bourcier ◽  
Emily G. Lowery-Gionta
Keyword(s):  
Alcohol Use ◽  
Animal Models ◽  
Alcohol Use Disorder ◽  
The Brain

Modification of cue-reactivity by neurofeedback in Alcohol Use Disorder

2019 ◽  
Author(s):  
P Halli ◽  
MF Gerchen ◽  
F Kiefer ◽  
P Kirsch
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Cue Reactivity

Prospective Memory Deficits in Patients With Alcohol Use Disorder

2019 ◽  
Vol 20 (2) ◽  
pp. 85-101
Author(s):  
In-Hwa Hong ◽  
◽  
Myung-Sun Kim
Keyword(s):  
Alcohol Use ◽  
Prospective Memory ◽  
Alcohol Use Disorder ◽  
Memory Deficits
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