scholarly journals Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles

2013 ◽  
Vol 65 (13-14) ◽  
pp. 1686-1698 ◽  
Author(s):  
Chiranjeevi Peetla ◽  
Sivakumar Vijayaraghavalu ◽  
Vinod Labhasetwar
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Cell Membrane ◽  
Drug Transport ◽  
Membrane Lipids ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Nanoparticle-based drug delivery systems with platinum drugs for overcoming cancer drug resistance

2021 ◽  
Author(s):  
Peng Xie ◽  
Yushu Wang ◽  
Dengshuai Wei ◽  
Lingpu Zhang ◽  
Bin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cancer Drug ◽  
Platinum Drugs ◽  
Effective Strategy ◽  
Platinum Drug ◽  
Cancer Drug Resistance ◽  
Platinum Drug Resistance

The mechanisms of chemoresistance and nanoparticle-based drug delivery systems for platinum drugs were detailed summarized in this review. The current combination therapy provided an effective strategy to overcome the platinum drug resistance.

Subcellular-Scale Drug Transport via Ultrasound-Degradable Mesoporous Nanosilicon to Bypass Cancer Drug Resistance

Small ◽  
2017 ◽  
Vol 13 (20) ◽  
pp. 1604228 ◽  
Author(s):  
Bin Kang ◽  
Ming-Bo Zheng ◽  
Pei Song ◽  
Ai-Ping Chen ◽  
Ji-Wu Wei ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Drug Transport ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Lipid–polymer hybrid nanoparticles for synergistic drug delivery to overcome cancer drug resistance

2017 ◽  
Vol 41 (4) ◽  
pp. 1518-1525 ◽  
Author(s):  
Shao-Qi Zeng ◽  
Yi-Zhen Chen ◽  
Yong Chen ◽  
Hong Liu
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Chemotherapeutic Drug ◽  
Cancer Drug Resistance ◽  
Polymer Hybrid ◽  
Tumor Drug Resistance

Co-delivery of a chemotherapeutic drug and a drug resistance inhibitor by lipid–polymer hybrid nanoparticles can effectively overcome tumor drug resistance.

scholarly journals Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics

2021 ◽  
Author(s):  
Anna Ulldemolins ◽  
Joaquin Seras-Franzoso ◽  
Fernanda Andrade ◽  
Diana Rafael ◽  
Ibane Abasolo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Fanconi Anemia DNA Repair Pathway as a New Mechanism to Exploit Cancer Drug Resistance

2020 ◽  
Vol 20 (9) ◽  
pp. 779-787
Author(s):  
Kajal Ghosal ◽  
Christian Agatemor ◽  
Richard I. Han ◽  
Amy T. Ku ◽  
Sabu Thomas ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Dna Repair ◽  
Fanconi Anemia ◽  
Cancer Drug ◽  
Drug Resistant ◽  
Cancer Drugs ◽  
Repair Pathway ◽  
Cancer Drug Resistance ◽  
Anti Cancer ◽  
Cancerous Cells

Chemotherapy employs anti-cancer drugs to stop the growth of cancerous cells, but one common obstacle to the success is the development of chemoresistance, which leads to failure of the previously effective anti-cancer drugs. Resistance arises from different mechanistic pathways, and in this critical review, we focus on the Fanconi Anemia (FA) pathway in chemoresistance. This pathway has yet to be intensively researched by mainstream cancer researchers. This review aims to inspire a new thrust toward the contribution of the FA pathway to drug resistance in cancer. We believe an indepth understanding of this pathway will open new frontiers to effectively treat drug-resistant cancer.

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