Lipid–polymer hybrid nanoparticles for synergistic drug delivery to overcome cancer drug resistance

2017 ◽  
Vol 41 (4) ◽  
pp. 1518-1525 ◽  
Author(s):  
Shao-Qi Zeng ◽  
Yi-Zhen Chen ◽  
Yong Chen ◽  
Hong Liu
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Chemotherapeutic Drug ◽  
Cancer Drug Resistance ◽  
Polymer Hybrid ◽  
Tumor Drug Resistance

Co-delivery of a chemotherapeutic drug and a drug resistance inhibitor by lipid–polymer hybrid nanoparticles can effectively overcome tumor drug resistance.

Biotinylated carboxymethyl chitosan/CaCO3 hybrid nanoparticles for targeted drug delivery to overcome tumor drug resistance

RSC Advances ◽  
2016 ◽  
Vol 6 (73) ◽  
pp. 69083-69093 ◽  
Author(s):  
Jin-Long Wu ◽  
Xiao-Yan He ◽  
Pei-Yuan Jiang ◽  
Meng-Qing Gong ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Tumor Cells ◽  
Targeted Drug Delivery ◽  
Carboxymethyl Chitosan ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Tumor Drug Resistance ◽  
Anti Cancer ◽  
Targeted Drug

A tumor targeted nano-sized self-assembled drug delivery system could efficiently co-deliver an anti-cancer drug and a drug resistance inhibitor to tumor cells and achieve an improved therapeutic efficiency through inhibition of P-gp function.

Nanoparticle-based drug delivery systems with platinum drugs for overcoming cancer drug resistance

2021 ◽  
Author(s):  
Peng Xie ◽  
Yushu Wang ◽  
Dengshuai Wei ◽  
Lingpu Zhang ◽  
Bin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cancer Drug ◽  
Platinum Drugs ◽  
Effective Strategy ◽  
Platinum Drug ◽  
Cancer Drug Resistance ◽  
Platinum Drug Resistance

The mechanisms of chemoresistance and nanoparticle-based drug delivery systems for platinum drugs were detailed summarized in this review. The current combination therapy provided an effective strategy to overcome the platinum drug resistance.

NiFe2O4/poly(ethylene glycol)/lipid–polymer hybrid nanoparticles for anti-cancer drug delivery

2020 ◽  
Vol 44 (42) ◽  
pp. 18162-18172
Author(s):  
K. S. Joshy ◽  
Robin Augustine ◽  
Anshida Mayeen ◽  
Susan M. Alex ◽  
Anwarul Hasan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Nickel Ferrite ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Poly Ethylene Glycol ◽  
Polymer Hybrid ◽  
Anti Cancer ◽  
Poly Ethylene ◽  
Cancer Drug Delivery

The present study reports the fabrication of hybrid nanoparticles consisting of nickel ferrite (NFO) for anti cancer drug delivery.

scholarly journals Exosomes: A New Pathway for Cancer Drug Resistance

2021 ◽  
Vol 11 ◽  
Author(s):  
Yunbin Zhong ◽  
Haibo Li ◽  
Peiwen Li ◽  
Yong Chen ◽  
Mengyao Zhang ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Current Knowledge ◽  
Cell Types ◽  
Bioactive Molecules ◽  
Cancer Drug ◽  
Cancer Drug Resistance ◽  
Tumor Drug Resistance ◽  
Cells Of Origin ◽  
Potential Applications ◽  
Multiple Cell

Exosomes are extracellular vesicles (EVs) that are secreted into body fluids by multiple cell types and are enriched in bioactive molecules, although their exact contents depend on the cells of origin. Studies have shown that exosomes in the tumor microenvironment affect tumor growth, metastasis and drug resistance by mediating intercellular communication and the transport of specific molecules, although their exact mechanisms of action need to be investigated further. In this review, we have summarized current knowledge on the relationship between tumor drug resistance and exosomes, and have discussed the potential applications of exosomes as diagnostic biomarkers and therapeutic targets.

Fusion peptide functionalized hybrid nanoparticles for synergistic drug delivery to reverse cancer drug resistance

2017 ◽  
Vol 5 (24) ◽  
pp. 4697-4704 ◽  
Author(s):  
Jin-Long Wu ◽  
Xiao-Yan He ◽  
Bo-Ya Liu ◽  
Meng-Qing Gong ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Fusion Peptide ◽  
Hybrid Nanoparticles ◽  
Cancer Drug ◽  
Inorganic Hybrid ◽  
Assembly Strategy ◽  
Cancer Drug Resistance ◽  
Functional Peptides

A facile self-assembly strategy was developed to decorate polymer/inorganic hybrid nano-sized drug delivery systems with functional peptides.

scholarly journals Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics

2021 ◽  
Author(s):  
Anna Ulldemolins ◽  
Joaquin Seras-Franzoso ◽  
Fernanda Andrade ◽  
Diana Rafael ◽  
Ibane Abasolo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cancer Drug ◽  
Cancer Drug Resistance
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