International uveal melanoma incidence trends in view of a decreasing proportion of morphological verification

BackgroundIn the developed countries, uveal melanoma is the most common primary intraocular malignancy in adults. Little is known about the epidemiological and geographical distribution of uveal melanoma in Canada.MethodsTo determine the incidence patterns and geographical distribution of uveal melanoma cases in Canada, we conducted the first comprehensive, population-based national study of this malignancy across all Canadian provinces and territories during 1992–2010 years. We examined two independent population-based registries: the Canadian Cancer Registry and Le Registre Québécois du Cancer using corresponding International Classification of Diseases for Oncology-3rd edition codes for all histological subtypes of uveal melanoma.ResultsWe report that 2215 patients were diagnosed with uveal melanoma, of which 52.1% were males. The average -annual incidence rate of uveal melanoma in Canada was 3.75 cases per million individuals per year (95% CI 3.60 to 3.91). Overall, we report a steady increase in uveal melanoma incidence with an annual increase of 0.074 cases per million individuals per year. Significant differences in the incidence rates of uveal melanoma between Canadian provinces and territories were noted, where the highest crude incidence was in British Columbia and Saskatchewan with rates of 6.38 and 5.47 cases per million individuals per year, respectively.ConclusionsThis work, for the first time, defines the disease burden of uveal melanoma in Canada and highlights important longitudinal, geographical and spatial differences in the distribution of uveal melanoma in Canada.

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Melanoma incidence trends in Limburg after screening and prevention campaigns

Archives of Public Health ◽

10.1186/0778-7367-68-1-1 ◽

2010 ◽

Vol 68 (1) ◽

Cited By ~ 1

Author(s):

D Vanstraelen ◽

H Deleu ◽

J Van Robays ◽

D Dhollander ◽

E Cloes ◽

...

Keyword(s):

Incidence Trends ◽

Melanoma Incidence ◽

Screening And Prevention

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Melanoma Incidence Among Non-Hispanic Whites in All 50 US States From 2001 Through 2015

JNCI Journal of the National Cancer Institute ◽

10.1093/jnci/djz153 ◽

2019 ◽

Vol 112 (5) ◽

pp. 533-539 ◽

Cited By ~ 6

Author(s):

Aaron P Thrift ◽

Franciska J Gudenkauf

Keyword(s):

Incidence Rate ◽

Birth Cohort ◽

Sun Exposure ◽

The United States ◽

Incidence Rates ◽

Birth Cohorts ◽

Annual Percent Change ◽

Incidence Trends ◽

Percent Change ◽

Melanoma Incidence

Abstract Background The United States has large regional variation in primary prevention campaigns for skin cancer. We collected data from all 50 states to examine changes in melanoma incidence and performed age-period-cohort analyses to describe the simultaneous effects of age, period, and cohort on incidence rates. Methods Annual melanoma incidence rates for non-Hispanic whites from 2001 to 2015 were extracted from the US Cancer Statistics registry. Secular trends were examined overall and by sex and state. We used joinpoint regression to compute annual percent change and average annual percent change and corresponding 95% confidence intervals (CIs). We also analyzed incidence trends by 5-year age group and birth cohort using incidence rate ratios and age-period-cohort modeling. Results Melanoma incidence increased from 20.7 per 100 000 (95% CI = 20.5 to 20.9) in 2001 to 28.2 per 100 000 (95% CI = 28.0 to 28.5) in 2015, increasing by 3.90% (95% CI = 2.36% to 5.48%) annually between 2001 and 2005 and 1.68% (95% CI = 1.37% to 1.99%) annually from 2005 through 2015. The average annual percent change in melanoma incidence rates were similar for men (2.34%, 95% CI = 1.91 to 2.78) and women (2.25%, 95% CI = 1.60 to 2.91). Age-specific relative risk by birth cohort increased from circa 1921 to 1981 before decreasing. Compared with adults born circa 1956, those born circa 1991 had lower melanoma risk (incidence rate ratio = 0.85; 95% CI = 0.77 to 0.94). Geographic variation was observed; some states still have melanoma rates trending upwards in all birth cohorts. Conclusions The continued increase in melanoma incidence among non-Hispanic whites, particularly in states where rates continue to rise among recent and current birth cohorts, underscores the need for increased public health campaigns aimed at reducing sun exposure.

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Comparison of state and national melanoma incidence trends using data from the Florida Cancer Data System (FCDS) and the Surveillance, Epidemiology, and End Results (SEER) program, 1992-2004

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2008.11.077 ◽

2009 ◽

Vol 60 (3) ◽

pp. AB11

Keyword(s):

Data System ◽

Seer Program ◽

Cancer Data ◽

Incidence Trends ◽

Melanoma Incidence ◽

Using Data ◽

End Results

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The acceleration of melanoma in situ: A population-based study of melanoma incidence trends from Victoria, Australia, 1985-2015

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2018.12.067 ◽

2019 ◽

Vol 80 (6) ◽

pp. 1791-1793 ◽

Cited By ~ 2

Author(s):

David J. Curchin ◽

Emily Forward ◽

Philippa Dickison ◽

Victoria R. Harris ◽

Chris J. McCormack ◽

...

Keyword(s):

Population Based ◽

Population Based Study ◽

Incidence Trends ◽

Melanoma In Situ ◽

Melanoma Incidence

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Vasocentric fascicular uveal melanoma. Incidence and re-appraisal of the histological features

British Journal of Ophthalmology ◽

10.1136/bjo.2007.114108 ◽

2007 ◽

Vol 92 (1) ◽

pp. 147-149 ◽

Cited By ~ 2

Author(s):

I Pecorella ◽

P Grenga ◽

E M Vingolo ◽

A Ciardi

Keyword(s):

Uveal Melanoma ◽

Histological Features ◽

Melanoma Incidence

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Changing Trends in Melanoma Incidence and Decreasing Melanoma Mortality in Hungary Between 2011 and 2019: A Nationwide Epidemiological Study

Frontiers in Oncology ◽

10.3389/fonc.2020.612459 ◽

2021 ◽

Vol 10 ◽

Author(s):

Gabriella Liszkay ◽

Zoltan Kiss ◽

Roland Gyulai ◽

Judit Oláh ◽

Péter Holló ◽

...

Keyword(s):

Mortality Rates ◽

Incidence Rates ◽

Recent Change ◽

Insurance Fund ◽

Male Population ◽

Awareness Campaigns ◽

Incidence Trends ◽

Melanoma Incidence ◽

Central Statistical ◽

Central Statistical Office

BackgroundThe incidence of malignant melanoma has continually increased during the past few decades, however, certain reports suggest a recent change in trends. The aim of our study was to examine the epidemiology of melanoma in Hungary.MethodsThis nationwide, retrospective, longitudinal study included melanoma patients diagnosed between 1 January 2009 and 31 December 2019 using the databases of the National Health Insurance Fund (NHIF) and Central Statistical Office (CSO) of Hungary. Age-standardized incidence and cause-specific mortality rates were calculated.ResultsWe identified 2,426 and 2,414 new melanoma cases in 2011 and in 2019. Age-standardized incidence rates were higher in males and varied between 28.28 and 34.57/100,000 person-years (PYs), and between 22.63 and 26.72/100,000 PYs in females. We found 16.14 and 18.82% increases in male and female incidence rates from 2011 to 2015 (p=0.067 and p<0.001, respectively), and 12.77 and 11.35% decreases from 2015 to 2019 (p=0.062 and p=0.004, respectively). The change of incidence trends (2011–2015 vs. 2015–2019) was significant in females (p=0.002) and in the total melanoma population (p=0.011), but not in the male population (p=0.063). A 16.55% (95% CI: −27.07 to −4.59; p=0.013) decrease in mortality rates was found in the overall melanoma population.ConclusionsWe observed a significant trend change in melanoma incidence in the female and total melanoma population, and a significant decrease in mortality in the total melanoma population. These changes may be attributed to intensive melanoma awareness campaigns as well as to the increase in screening and access to modern therapies.

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