scholarly journals 727: Neonatal morbidity and mortality associated with induction of labor at 39 weeks versus expectant management

2020 ◽  
Vol 222 (1) ◽  
pp. S460-S461
Author(s):  
Sabrina Burn ◽  
Ruofan Yao ◽  
Jordan Rossi ◽  
Maria Diaz ◽  
Stephen Contag
Author(s):  
Sabrina Burn ◽  
Ruofan Yao ◽  
Maria Diaz ◽  
Jordan Rossi ◽  
Stephen Contag

Objective: To determine maternal and neonatal morbidity associated with induction of labor at 39 weeks compared with expectant management through 42 weeks. Design: Cohort study Setting & Population: Low risk American women who delivered between 39 and 42 weeks in 2015 to 2017. Methods: Data was abstracted from the national vital statistics database. Multivariable log-binomial regression analysis was conducted to estimate the relative risk of morbidity. Main Outcome Measures: Maternal morbidity included Triple I, blood transfusion, ICU admission, uterine rupture, cesarean hysterectomy, and cesarean delivery. Neonatal morbidity included 5 minute Apgar ≤3, prolonged ventilation, seizures, NICU admission, and neonatal death. Results: A total of 1,885,694 women were included for analysis. Women undergoing induction of labor at 39 weeks were less likely to develop Triple I (p-value < 0.001; aRR 0.66; 95% CI [0.64-0.68]) and require a cesarean section (p-value <0.01; aRR 0.69l 95% CI [0.68-0.69]) than the expectant management group. There was a small, but significant increase in cesarean hysterectomy in the induction group (p-value <0.01; aRR 1.32; 95% CI [1.05-1.65]). Neonates of the induction group were less likely to have 5 minute Apgar ≤3 (p-value < 0.01; aRR 0.69; 95% CI [0.64-0.74]), prolonged ventilation (p-value < 0.01; aRR 0.77; 95% CI [0.72-0.82]), NICU admission (p-value < 0.01; aRR 0.80; 95% CI [0.79-0.82]), and/or neonatal seizures (p-value <0.01; aRR 0.80; 95% CI [0.66-0.98]) compared to the expectant management group. Conclusions: Induction of labor at 39 weeks gestation compared with expectant management is not harmful and has maternal and neonatal benefits.


2008 ◽  
Vol 15 (02) ◽  
pp. 216-219
Author(s):  
MISBAH KAUSAR JAVAI JAVAID ◽  
SAMIA HASSAN ◽  
TAYYABA TAHIRA

To find outmaternal and fetal outcome in induction of labourcompared with expectant management for prelabour rupture of membranes at term. Design: Open randomizedcomparative study. Setting and period: Gynae Unit- II Services Hospital, from 1 April 2007 to 30 September 2007. stPatient and methods: 100 patients at > 37 weeks with ruptures membranes with no contraindication to vaginal deliverywere enrolled in the study. 50 patients were in the expectant group while 50 patients were in the induction group.Results: Both groups had the same general characteristics but the Misoprostol group had a significantly shorter latancyperiod (10-16 hour Vs 20-24 hours), shorter period of hospitalization, lesser LSCS rate (24% Vs 34%) lesser need ofaugmentation (40% Vs 62%), choroamnionitis (3%Vs 7.8%), and postpartumfever (1% Vs 1.8%) when compared withexpectant group. Rate of infected wound after LSCS were compared in induction and expectant groups (2.2% Vs2.6%), also there was no difference between them regarding neonatal morbidity and nursery admission. Conclusion:So it was concluded that there was slightly high maternal complications in expectant group but no long-term maternalmorbidity. Both groups have no effect on neonatal morbidity and mortality however the duration between PROM anddelivery effect the neonatal admission in nursery and antibiotic requirements.


Author(s):  
Teresa Janevic ◽  
Jennifer Zeitlin ◽  
Natalia N. Egorova ◽  
Paul Hebert ◽  
Amy Balbierz ◽  
...  

2021 ◽  
Vol 224 (2) ◽  
pp. S474
Author(s):  
Alyssa R. Hersh ◽  
Eleanor M. Schmidt ◽  
Claire H. Packer ◽  
Bharti Garg ◽  
Aaron B. Caughey

2012 ◽  
Vol 206 (1) ◽  
pp. S8-S9
Author(s):  
David van der Ham ◽  
Jantien van der Heijden ◽  
Brent Opmeer ◽  
Hans van Beek ◽  
Christine Willekes ◽  
...  

2017 ◽  
Vol 45 (1) ◽  
Author(s):  
Winnie Huiyan Sim ◽  
Edward Araujo Júnior ◽  
Fabricio Da Silva Costa ◽  
Penelope Marie Sheehan

AbstractAim:To assess the contemporary maternal and neonatal outcomes following expectant management of preterm premature rupture of membranes (PPROM) prior to 24 weeks’ gestation and to identify prognostic indicators of this morbid presentation.Methods:We performed a systematic review in the Pubmed and EMBASE databases to identify the primary (perinatal mortality, severe neonatal morbidity and serious maternal morbidity) and secondary (neonatal survival and morbidity) outcomes following expectant management of previable PPROM.Results:Mean latency between PPROM and delivery ranged between 20 and 43 days. Women with PPROM <24 weeks had an overall live birth rate of 63.6% and a survival-to-discharge rate of 44.9%. The common neonatal morbidities were respiratory distress syndrome, bronchopulmonary dysplasia and sepsis. The majority of neonatal deaths within 24 h post birth were associated with pulmonary hypoplasia, severe intraventricular haemorrhage and neonatal sepsis. The common maternal outcomes were chorioamnionitis and caesarean sections. The major predictors of neonatal survival were later gestational age at PPROM, adequate residual amniotic fluid levels, C-reactive protein <1 mg/dL within 24 h of admission and PPROM after invasive procedures.Conclusion:Pregnancy latency and neonatal survival following previable PPROM has improved in recent years, although neonatal morbidity remains unchanged despite recent advances in obstetric and neonatal care. There is heterogeneity in management practices across centres worldwide.


2021 ◽  
pp. 1-9
Author(s):  
Clara Opha Haruzivishe

Background: High Maternal and Neonatal Mortality Ratios persist in Sub-Saharan Africa despite increasing perinatal care coverage. This suggests that coverage alone is not adequate to reduce maternal and neonatal morbidity and mortality. Quality of care should be the emphasis of maternal and child care services. Materials and Methods: A descriptive cross-sectional multicentre study was conducted in selected health facilities in Zambia, Malawi and Zimbabwe using purposive sampling. A World Health Organization-WHO 2016 Quality of Maternal and New-born assessment Framework and the WHO (2015) Service Availability and Readiness Assessment tool were used for data collection. Data was analyzed using Statistical Package for Social Scientist (SPSS) version 24.0. Results: Less than 43% of the health facilities satisfied at least three of the five Performance Standards of availability and adequacy of Antenatal infrastructure and supplies. Regarding Antenatal processes/care, an observation was the most common performance standard satisfied by 70.6% of all health facilities assessed while less than 30% fulfilled all other standards. Only 57.1% of the health facilities satisfied 5 of the 11 standards for labour and delivery infrastructure, while only 55.6% of the Health facilities satisfied only two of the 13 standards of Labour and delivery care. Conclusion: To achieve a significant and sustainable reduction in maternal and neonatal morbidity and mortality, there is a need for investment and improvement in maternity care services infrastructure and processes as opposed to focusing on mere attendance of Antenatal, and deliveries by trained birth attendants.


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