Influence of BMI on adverse perinatal outcomes in women undergoing ToLAC in preterm delivery

BackgroundLow birth weight, prematurity and higher miscarriage rates have previously been reported in women with eating disorders.AimsTo determine whether women with a history of eating disorders are at higher risk of major adverse perinatal outcomes.MethodsAdjusted birth weight, preterm delivery and miscarriage history were compared in those with a history of eating disorders (anorexia nervosa (n=171), bulimia nervosa (n=199) and both (n=82)) and those with other (n=1166) and no psychiatric disorders (n=10 636) in a longitudinal cohort study.ResultsThe group with bulimia nervosa had significantly higher rates of past miscarriages (relative risk ratio 2.0, P=0.01) and the group with anorexia nervosa delivered babies of significantly lower birth weight than the general population (P=0.01), which was mainly explained by lower pre-pregnancy body mass index. Preterm delivery rates were comparable across groups.ConclusionsWomen with a history of eating disorders are at higher risk of major adverse obstetric outcomes. Antenatal services should be aware of this higher risk.

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Case Series of Intrauterine Subamniotic Hemorrhage

Case Reports in Obstetrics and Gynecology ◽

10.1155/2019/1828457 ◽

2019 ◽

Vol 2019 ◽

pp. 1-4

Author(s):

Momoko Owada ◽

Yoshie Shibata ◽

Shunji Suzuki

Keyword(s):

Preterm Delivery ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Clinical Characteristics ◽

Case Series ◽

Perinatal Outcomes ◽

The Other ◽

Second Trimester ◽

Definite Diagnosis ◽

Adverse Perinatal Outcomes

We present here 9 cases of intrauterine subamniotic hemorrhage to describe the pathological sequence. The definite diagnosis of subamniotic hemorrhage was mainly made macroscopically with the presence of hemorrhage or hematoma wrapped in the membrane on the fetal surface by postnatal examining of the placenta. In 7 of them (78%), the presence of gradual subamniotic hemorrhage in the second trimester of pregnancy was suspected. In the cases, severe fetal growth restriction and preterm delivery were recognized in 2 (29%) and 4 cases (57%), respectively. In the other 2 cases (22%), acute anemia associated with acute subamniotic hemorrhage was clinically suspected. This may be the first report examining the clinical characteristics of acute or gradual intrauterine subamniotic hemorrhage. Both patterns of subamniotic hemorrhage seemed to be associated with the adverse perinatal outcomes.

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Faculty Opinions recommendation of Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727327812.793534615 ◽

2017 ◽

Author(s):

Philippe Le Bouteiller

Keyword(s):

Virus Infection ◽

Zika Virus ◽

Perinatal Outcomes ◽

Transplacental Transmission ◽

Zika Virus Infection ◽

Adverse Perinatal Outcomes ◽

Immunocompetent Mice

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Pregnancy Outcomes and SARS-CoV-2 Infection: The Spanish Obstetric Emergency Group Study

Viruses ◽

10.3390/v13050853 ◽

2021 ◽

Vol 13 (5) ◽

pp. 853

Author(s):

Sara Cruz Melguizo ◽

María Luisa de la Cruz Conty ◽

Paola Carmona Payán ◽

Alejandra Abascal-Saiz ◽

Pilar Pintando Recarte ◽

...

Keyword(s):

Pregnant Women ◽

Perinatal Outcomes ◽

Preterm Births ◽

Hypertensive Disorder ◽

Obstetric Emergency ◽

Increased Risk ◽

Emergency Group ◽

Adverse Perinatal Outcomes ◽

Maternal Disease ◽

The Relationship

Pregnant women who are infected with SARS-CoV-2 are at an increased risk of adverse perinatal outcomes. With this study, we aimed to better understand the relationship between maternal infection and perinatal outcomes, especially preterm births, and the underlying medical and interventionist factors. This was a prospective observational study carried out in 78 centers (Spanish Obstetric Emergency Group) with a cohort of 1347 SARS-CoV-2 PCR-positive pregnant women registered consecutively between 26 February and 5 November 2020, and a concurrent sample of PCR-negative mothers. The patients’ information was collected from their medical records, and the association of SARS-CoV-2 and perinatal outcomes was evaluated by univariable and multivariate analyses. The data from 1347 SARS-CoV-2-positive pregnancies were compared with those from 1607 SARS-CoV-2-negative pregnancies. Differences were observed between both groups in premature rupture of membranes (15.5% vs. 11.1%, p < 0.001); venous thrombotic events (1.5% vs. 0.2%, p < 0.001); and severe pre-eclampsia incidence (40.6 vs. 15.6%, p = 0.001), which could have been overestimated in the infected cohort due to the shared analytical signs between this hypertensive disorder and COVID-19. In addition, more preterm deliveries were observed in infected patients (11.1% vs. 5.8%, p < 0.001) mainly due to an increase in iatrogenic preterm births. The prematurity in SARS-CoV-2-affected pregnancies results from a predisposition to end the pregnancy because of maternal disease (pneumonia and pre-eclampsia, with or without COVID-19 symptoms).

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Fetal movement counting is associated with the reduction of delayed maternal reaction after perceiving decreased fetal movements: a prospective study

Scientific Reports ◽

10.1038/s41598-021-90240-4 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Shigeki Koshida ◽

Shinsuke Tokoro ◽

Daisuke Katsura ◽

Shunichiro Tsuji ◽

Takashi Murakami ◽

...

Keyword(s):

Pregnant Women ◽

Maternal Behavior ◽

Multivariable Analysis ◽

Perinatal Outcomes ◽

Fetal Movement ◽

Post Intervention ◽

Fetal Movements ◽

Adverse Perinatal Outcomes ◽

The Impact ◽

Maternal Reaction

AbstractMaternal perception of decreased fetal movement is associated with adverse perinatal outcomes. Although there have been several studies on interventions related to the fetal movements count, most focused on adverse perinatal outcomes, and little is known about the impact of the fetal movement count on maternal behavior after the perception of decreased fetal movement. We investigated the impact of the daily fetal movement count on maternal behavior after the perception of decreased fetal movement and on the stillbirth rate in this prospective population-based study. Pregnant women in Shiga prefecture of Japan were asked to count the time of 10 fetal movements from 34 weeks of gestation. We analyzed 101 stillbirths after the intervention compared to 121 stillbirths before the intervention. In multivariable analysis, maternal delayed visit to a health care provider after the perception of decreased fetal movement significantly reduced after the intervention (aOR 0.31, 95% CI 0.11–0.83). Our regional stillbirth rates in the pre-intervention and post-intervention periods were 3.06 and 2.70 per 1000 births, respectively. Informing pregnant women about the fetal movement count was associated with a reduction in delayed maternal reaction after the perception of decreased fetal movement, which might reduce stillbirths.

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