Establishment of a minimally invasive program at a Veterans' Affairs Medical Center leads to improved care in colorectal cancer patients

2009 ◽  
Vol 198 (5) ◽  
pp. 685-692 ◽  
Author(s):  
Jonathan A. Wilks ◽  
Courtney J. Balentine ◽  
David H. Berger ◽  
Daniel Anaya ◽  
Samir Awad ◽  
...  
Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2410
Author(s):  
Chungyeop Lee ◽  
In-Ja Park ◽  
Kyung-Won Kim ◽  
Yongbin Shin ◽  
Seok-Byung Lim ◽  
...  

The effect of perioperative sarcopenic changes on prognosis remains unclear. We conducted a retrospective cohort study with 2333 non-metastatic colorectal cancer patients treated between January 2009 and December 2012 at the Asan Medical Center. The body composition at diagnosis was measured via abdominopelvic computed tomography (CT) using Asan-J software. Patients underwent CT scans preoperatively, as well as at 6 months–1 year and 2–3 years postoperatively. The primary outcome was the association between perioperative sarcopenic changes and survival. According to sarcopenic criteria, 1155 (49.5%), 890 (38.2%), and 893 (38.3%) patients had sarcopenia preoperatively, 6 months–1 year, and 2–3 years postoperatively, respectively. The 5-year overall survival (OS) (95.8% vs. 92.1%, hazard ratio (HR) = 2.234, p < 0.001) and 5-year recurrence-free survival (RFS) (93.2% vs. 86.2%, HR = 2.251, p < 0.001) rates were significantly lower in patients with preoperative sarcopenia. Both OS and RFS were lower in patients with persistent sarcopenia 2–3 years postoperatively than in those who recovered (OS: 96.2% vs. 90.2%, p = 0.001; RFS: 91.1% vs. 83.9%, p = 0.002). In multivariate analysis, postoperative sarcopenia was confirmed as an independent factor associated with decreased OS and RFS. Pre- and postoperative sarcopenia and changes in the condition during surveillance were associated with oncological outcomes.


2011 ◽  
Vol 166 (2) ◽  
pp. 182-188 ◽  
Author(s):  
Celia N. Robinson ◽  
Courtney J. Balentine ◽  
Christy L. Marshall ◽  
Jonathan A. Wilks ◽  
Daniel Anaya ◽  
...  

2010 ◽  
Vol 158 (2) ◽  
pp. 271
Author(s):  
C.N. Robinson ◽  
C.J. Balentine ◽  
C.L. Marshall ◽  
J.A. Wilks ◽  
D.A. Anaya ◽  
...  

2009 ◽  
Vol 198 (1) ◽  
pp. 100-104 ◽  
Author(s):  
Jonathan A. Wilks ◽  
Catherine Liebig ◽  
Syed H. Tasleem ◽  
Kujtim Haderxhanaj ◽  
Liz Lee ◽  
...  

2012 ◽  
Vol 53 (2) ◽  
pp. 498-510 ◽  
Author(s):  
Leah L. Zullig ◽  
George L. Jackson ◽  
Dawn Provenzale ◽  
Joan M. Griffin ◽  
Sean Phelan ◽  
...  

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