P446 Allergic rhinitis: 3 years experience of sensitization in children by skin prick test in Mexico

A remarkable relationship exists between upper and lower airways. Bronchial obstruction is a paramount feature of asthma as well as nasal obstruction of allergic rhinitis (AR). This study aims to evaluate the response to both bronchodilation and decongestion testing and their relationships in a large group of patients with moderate-severe persistent AR alone. Two hundred eleven patients with moderate-severe persistent AR were prospectively and consecutively evaluated. Clinical examination, skin prick test, spirometry, bronchodilation test, rhinomanometry, and decongestion test were performed on all patients. Seventeen subjects (8%) did not respond to any of the tests, 55 subjects (26.1%) were responders only to the decongestion test, 31 (14.7%) only to the bronchodilation test, and 108 subjects (51.2%) responded to both these tests. Longer AR duration was significantly associated with positive response to both tests (p<0.01). In conclusion, this study provides the first evidence that patients with moderate-severe persistent AR may frequently show reversibility to both bronchodilation and decongestion tests.

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Study of causal aeroallergens in allergic rhinitis

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20192556 ◽

2019 ◽

Vol 5 (4) ◽

pp. 916

Author(s):

Divya Aggarwal ◽

Abhilash S. ◽

Sunil Kapur ◽

Divya Gupta

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Symptom Score ◽

Eosinophil Count ◽

Severe Disease ◽

Nasal Symptom ◽

Total Serum ◽

Serum Ige ◽

Prick Test ◽

Absolute Eosinophil Count

Background: The diagnosis of allergic rhinitis requires a detailed history, thorough clinical examination and identification of aeroallergens by skin prick test. The diagnosis cannot be confirmed on the basis of symptoms alone because both allergic and non-allergic rhinitis can present with similar symptoms. The present study was undertaken to identify the common aeroallergens causing allergic rhinitis and to find any relationship of the severity of patient’s symptoms with raised levels of absolute eosinophil count, percentage of eosinophils in the peripheral blood and total serum IgE.Methods: It is cross sectional study was conducted among 100 patients including both the genders attending out-patient department of ENT. The patients were divided into mild, moderate and severe disease categories based on nasal symptom score (NSS) which was calculated taking into account the severity of four symptoms namely sneezing, watery rhinorrhoea, itching sensation in nose and nasal obstruction. Results: 76% of patients had moderate nasal symptom score and 42% had symptoms of allergic rhinitis for less than 3 years. The prevalence of skin prick test was strongly positive for pollens (46.19%), followed by dust (16.4%), dust mites (15.7%), fungus (9.7%), insects (9.24%) and epithelia (2.77%). But, among 68 aeroallergens, most common offending allergen was D-farinae (30%). There was no significant relationship found to exist between Eosinophilia, Absolute eosinophil count and serum IgE level with that of nasal symptom score.Conclusions: Skin prick test is the gold standard investigation of choice for definitive diagnosis of allergic rhinitis.

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Correlation Analysis of two Serum-specific Immunoglobulin E Test Systems and Skin-Prick Test in Allergic Rhinitis Patients from Northeast China

American Journal of Rhinology and Allergy ◽

10.2500/ajra.2011.25.3572 ◽

2011 ◽

Vol 25 (2) ◽

pp. 116-119 ◽

Cited By ~ 11

Author(s):

Xiao-Dan Jiang ◽

Guang-Yu Li ◽

Zhen Dong ◽

Dong-Dong Zhu

Keyword(s):

Allergic Rhinitis ◽

Correlation Analysis ◽

Skin Prick Test ◽

Northeast China ◽

Immunoglobulin E ◽

Prick Test ◽

Test Systems ◽

Specific Immunoglobulin E ◽

Specific Immunoglobulin

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Skin Prick Test and Serum Specific IgE May Not Be Sufficient for the Diagnosis of Perennial Allergic Rhinitis in Atopic Patients

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2012.12.829 ◽

2013 ◽

Vol 131 (2) ◽

pp. AB41

Author(s):

Miguel Blanca ◽

Carmen Rondon ◽

Paloma Campo ◽

Francisca Gomez ◽

Rosa García Mendoza ◽

...

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Specific Ige ◽

Perennial Allergic Rhinitis ◽

Prick Test

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Analysis Of The Discordance Between Immunocap and Skin Prick Test For Common Allergens In Patients With Allergic Rhinitis Symptoms

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2013.12.189 ◽

2014 ◽

Vol 133 (2) ◽

pp. AB45

Author(s):

Do Yang Park ◽

Hyun Jun Kim ◽

Ju Wan Kang ◽

Yoo Suk Kim ◽

Chang-Hoon Kim

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Prick Test

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Skin prick test reactivity to aeroallergens in Jordanian allergic rhinitis patients

Eastern Mediterranean Health Journal ◽

10.26719/2011.17.7.604 ◽

2011 ◽

Vol 17 (07) ◽

pp. 604-610 ◽

Cited By ~ 11

Author(s):

S. Aburuz ◽

N. Bulatova ◽

M. Tawalbeh

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Prick Test

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Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital

Journal of Nepal Medical Association ◽

10.31729/jnma.5218 ◽

2020 ◽

Vol 58 (231) ◽

Author(s):

Monika Pokharel ◽

Bikash Lal Shrestha ◽

Dharmendra Karn ◽

Ashish Dhakal ◽

Abha Kiran K.C. ◽

...

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Data Entry ◽

Sampling Technique ◽

House Dust Mites ◽

Care Hospital ◽

Cross Sectional ◽

Prick Test

Introduction: The prevalence of allergic rhinitis has increased significantly globally over the last two decades. Detection of sensitizing aeroallergens plays a crucial role in the diagnosis and management of this troublesome disease. This study aims to investigate the spectrum of aeroallergens sensitization in patients with allergic rhinitis in a tertiary care hospital. Methods: A descriptive cross-sectional study conducted in the Department of Otorhinolaryngology of our hospital between January 2016 to December 2019. Ethical approval was taken from the Institutional Review Committee (No: 210/19). Patients diagnosed with allergic rhinitis were enrolled using the convenience sampling technique. Data entry and analysis was done using IBM Statistical Package for Social Sciences version 20.0. Results: Among 170 patients, altogether 103 (60.6%) patients yielded positive responses on the skin prick test. The most prevalent aeroallergens were Lepidoglyphus 86 (50.60%), Dermatophagoides pteronyssinus 85 (50%), Dermatophagoides farina 82 (48.20%), Thyrophagus 50 (29.40%), Blomia 46 (27.10%), Acarus 43 (25.30%), cat dander 26 (15.30%), dog dander 24 (14.10%), cow and buffalo dander 20 (11.8%), ragweed 20 (11.8%), grass pollen 18 (10.60%) and mugwort 17 (10%). Conclusions: This study highlights that the frequency of aeroallergens based on skin prick test in patients presenting to a tertiary care hospital which showed the dominance of house dust mites, dog and cat hair, pollen, and grasses. Reduced exposure and training of patients about protection against these agents will possibly help in controlling the severity of allergic rhinitis in this region.

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Soy Skin Prick Test in Patients with Physician-Diagnosed Atopic Disorders

QJM ◽

10.1093/qjmed/hcaa063.007 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

S M Reda ◽

N M Radwan ◽

H R Abdelghany

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Soy Protein ◽

Total Serum ◽

Positive Skin Prick Test ◽

Positive Skin ◽

Female Ratio ◽

Serum Ige ◽

Prick Test ◽

Protein Sensitization

Abstract Background Soy protein is an important component of soybeans and is one the 8 most significant food allergens. Yet, the prevalence of soy allergy in the pediatric population is not well defined. Objectives To evaluate the incidence of IgE mediated soy protein sensitization among children with clinical manifestation of atopic disorders by the use of skin prick test (SPT) for soy protein. Methods Two hundred patients with atopic manifestations attending the Pediatric Allergy and Immunology Clinic at the Pediatric Department of Ain shams University, were recruited between January 2017 till January 2018. They were subjected to SPT to soy protein, measurement of total serum IgE and eosinophilic count in the peripheral blood. Results Of the 200 patients, 108 (54%) were males and 92 (46%) were females with a male to female ratio of 1.17:1. Their ages ranged between 2 years and 15 years (mean±SD; 6.0±33.3 years). Seven patients (3.5%) had positive skin prick test to soy protein. The mean value for the absolute eosinophilic count was 0.4x109/L. The median for the total serum IgE level was 50 IU/L. According to age, the highest percentage of soy protein sensitivity was elicited among patients less than 3 years (57.14%), followed by those between 3 to 6 years (28.5%) and those between 6 and 15 years (14.28%). A positive family history of atopy was recorded in 122 (61%) of all cases. In terms of gender, incidence of soya sensitivity was higher among males than females but with no statistical difference. Although the most common allergic manifestations of all studied patients were respiratory (83%), and atopic dermatitis (22.5%), yet positive SPT to soy proteins was elicited in 43% in allergic rhinitis cases, in 29% of asthma patients, in 14% of patients with combined asthma and allergic rhinitis, and 14.3% of patients having eczema. Conclusion Soy protein sensitization is not uncommon in children especially in those with atopic manifestations. Large scale studies are needed to evaluate the actual incidence of soy protein hypersensitivity in children.

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Skin Prick Test Versus Phadiatop as a Tool for Diagnosis of Allergic Rhinitis in Children

American Journal of Rhinology and Allergy ◽

10.1177/1945892420938300 ◽

2020 ◽

Vol 35 (1) ◽

pp. 98-106

Author(s):

Sasiwimon Traiyan ◽

Wiparat Manuyakorn ◽

Watcharoot Kanchongkittiphon ◽

Cherapat Sasisakulporn ◽

Wanlapa Jotikasthira ◽

...

Keyword(s):

Allergic Rhinitis ◽

Skin Prick Test ◽

Provocation Test ◽

Specific Ige ◽

Prick Test ◽

The Past ◽

Negative Results ◽

Dust Mite ◽

The Mean ◽

Positive Results

Background Skin prick test (SPT) or Phadiatop, a multi-allergen IgE screening test, was used as a tool for detecting aeroallergen sensitization. Objective To compare SPT and Phadiatop as a tool for diagnosis allergic rhinitis (AR) using the nasal provocation test (NPT) as a comparative standard. Methods Children aged 5-18 years with rhinitis symptoms more than 6 times in the past year were enrolled. SPT to 13 common aeroallergens, serum for Phadiatop, and NPT to Dermatophagoides pteronyssinus (Der p) were performed. NPT to mixed cockroach (CR) were performed in children who had CR sensitization and negative NPT to Der p. Children who had a disagreement between the result of SPT and Phadiatop or having negative results were evaluated for specific IgE (sIgE) to common aeroallergens. Results One hundred-forty children were enrolled with the mean age of 9.8 ± 3 years, 56% were male. Of 92 children (65.7%) with positive SPT to any aeroallergens, 88 children (95.6%) were sensitized to house dust mite (HDM). NPT showed positive results in 97 children (69.3%). Of 48 children who showed negative SPT, 4 children (8.3%) had sIgE to aeroallergens but NPT was positive in 1 child. Eighty-eight children (62.9%) had positive tests for Phadiatop and 4 (4.5%) of them had negative results for NPT to Der p. Among 52 children who had negative results for Phadiatop, 4 children (7.6%) had sIgE to aeroallergens but NPT was positive in 2 children (3.8%). SPT and Phadiatop showed 94.2% agreement: with Kappa 0.876, p < 0.001. Using NPT as a comparative standard for diagnosis for AR, SPT showed a sensitivity of 89.6% and specificity of 88.3% and Phadiatop provided the sensitivity of 88.6% and specificity of 95.3%. Conclusions SPT to aeroallergen and Phadiatop have good and comparable sensitivity and specificity for the diagnosis of AR in children.

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