Validation of the ALEX microarray platform for specific IgE detection of respiratory and plant-food allergens

Author(s):  
Paola Leonor QUAN ◽  
Marina SABATÉ-BRESCÓ ◽  
Carmen Mariana D'AMELIO ◽  
Mariona PASCAL ◽  
Blanca Esther GARCÍA ◽  
...  
2002 ◽  
Vol 30 (6) ◽  
pp. 910-913 ◽  
Author(s):  
R. van Ree

Non-specific lipid transfer proteins (nsLTPs) have recently been identified as plant food allergens. They are good examples of true food allergens, in the sense that they are capable of sensitizing, i.e. inducing specific IgE, as well as of eliciting severe symptoms. This is in contrast with most plant food allergens, which are recognized because of primary sensitization to related inhalant allergens (cross-reactivity), i.e. pollen allergens. The basis of the difference between the latter category and strong food allergens such as nsLTPs appears to lie in the sensitivity of the allergens to proteolytic attack and food processing. Stability allows the allergen to reach the gastrointestinal immune system in an immunogenic and allergenic conformation, allowing sensitization and induction of systemic symptoms. Stability also explains the presence of such allergens in processed foods. Together, these characteristics make nsLTPs clinically highly relevant plant food allergens and ideal tools with which to study the mechanisms involved in food allergy.


10.2223/1184 ◽  
2004 ◽  
Vol 80 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Charles K. Naspitz ◽  
Dirceu Solé ◽  
Cristina A. Jacob ◽  
Emanuel Sarinho ◽  
Francisco J. P. Soares ◽  
...  
Keyword(s):  

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 679
Author(s):  
Monica Iuliana Ungureanu ◽  
Liliana Sachelarie ◽  
Radu Ciorap ◽  
Bogdan Aurelian Stana ◽  
Irina Croitoru ◽  
...  

Background and Objectives: Different types of food introduced gradually in the diet will expose children to different food allergens, increasing the chance of developing allergic diseases. The aim of our study was to determine if allergen-specific IgE values can influence, depending on the diet, the prediction of remission of urticaria in children. Materials and Methods: This prospective study was conducted in 132 patients diagnosed over two years with urticaria, admitted to “Sf. Maria” Clinical Pediatric Hospital Iaşi. Total IgE assay was performed by ELISA, and determination of specific serum IgE by the CLA System Quanti Scan method (Innogenetics, Heiden, Germany). Data were gathered and statistical analysis was performed using statistical software SPSS, using descriptive and inferential statistics. Results: The determination of specific IgE to food allergens was performed on a total of 132 cases. The values of specific IgE were positive for one or more food allergens in 84 patients (63.64%). The most common allergens involved were: cow’s milk in 33.3% cases, egg white in 22.6% cases, and hazelnuts in 11.9% cases. The specific IgE values for the different types of food included in our study had a predictive value for disease remission. Conclusions: The determination of specific IgE confirms the presence of a particular food allergen and may have predictive value for the future development of an allergic manifestation.


2006 ◽  
pp. 241-264
Author(s):  
E. N. Clare Mills ◽  
John A. Jenkins ◽  
Peter R. Shewry
Keyword(s):  

Author(s):  
Haziq Emran ◽  
Christina Siew Eng Chieng ◽  
Surita Taib ◽  
Anne Catherine Cunningham

AbstractIgE sensitisation in tropical areas is under-reported. A 2 year retrospective cohort study of allergy data specific to aero and food allergens in Brunei demonstrated that specific IgE levels to house dust mite (Dermatophagoides pteronyssinus, D.farinae, Blomia tropicalis) were highest in this population and correlated with atopic dermatitis (p < 0.001). Shrimp and peanut were the most common food allergens. A dominance of house/storage mite sensitization is seen in Brunei which is consistent with other tropical countries.


Allergy ◽  
2020 ◽  
Author(s):  
Riccardo Asero ◽  
Renato Ariano ◽  
Arianna Aruanno ◽  
Claudio Barzaghi ◽  
Paolo Borrelli ◽  
...  

1997 ◽  
Vol 46 (2) ◽  
pp. 125-133 ◽  
Author(s):  
Kazuko Kitamura ◽  
Chizuka Suga ◽  
Sumi Onuma ◽  
Toshiko Kawaguchi ◽  
Fusae Yamazaki ◽  
...  

2013 ◽  
Vol 61 (25) ◽  
pp. 6102-6112 ◽  
Author(s):  
Joyce Irene Boye ◽  
Allaoua Achouri ◽  
Nancy Raymond ◽  
Chantal Cleroux ◽  
Dorcas Weber ◽  
...  

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