Is p16 immunohistochemistry a more cost-effective method for identification of human papilloma virus–associated head and neck squamous cell carcinoma?

2012 ◽  
Vol 16 (2) ◽  
pp. 91-99 ◽  
Author(s):  
Jaiyeola Thomas ◽  
Thad Primeaux
2006 ◽  
Vol 132 (8) ◽  
pp. 897
Author(s):  
F. Gallegos-Hernandez ◽  
D. Hernandez ◽  
E. Paredes ◽  
R. Flores ◽  
G. Minauro ◽  
...  

2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P74-P74
Author(s):  
Sun M. Ahn ◽  
Jason Y. Chan ◽  
Wojciech K. Mydlarz ◽  
Xian-Chong Zhou ◽  
Jeremy D. Richmon ◽  
...  

2010 ◽  
Vol 124 (9) ◽  
pp. 941-944 ◽  
Author(s):  
C B Heffernan ◽  
J P O'Neill ◽  
C Timon

AbstractThere is considerable debate within the literature about the significance of human papilloma virus in head and neck squamous cell carcinoma, and its potential influence on the prevention, diagnosis, grading, treatment and prognosis of these cancers. Cigarette smoking and alcohol consumption have traditionally been cited as the main risk factors for head and neck cancers. However, human papilloma virus, normally associated with cervical and other genital carcinomas, has emerged as a possible key aetiological factor in head and neck squamous cell carcinoma, especially oropharyngeal cancers. These cancers pose a significant financial burden on health resources and are increasing in incidence. The recent introduction of vaccines targeted against human papilloma virus types 16 and 18, to prevent cervical cancer, has highlighted the need for ongoing research into the importance of human papilloma virus in head and neck squamous cell carcinoma.


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