P-255 The clinical significance of the gut microbiota in RAS wild-type metastatic colorectal cancer patients treated with anti-EGFR monoclonal antibodies in combination with chemotherapy – preliminary results

Cancer Patients ◽

Clinical Significance ◽

Wild Type ◽

Preliminary Results ◽

Impact of delayed addition of anti-EGFR monoclonal antibodies on the outcome of first-line therapy in metastatic colorectal cancer patients: A retrospective registry-based analysis

Annals of Oncology ◽

10.1093/annonc/mdy281.038 ◽

2018 ◽

Vol 29 ◽

pp. viii165

Author(s):

T. Buchler ◽

O. Fiala ◽

V. Veskrnova ◽

R. Chloupkova ◽

A. Poprach ◽

...

Keyword(s):

Colorectal Cancer ◽

Monoclonal Antibodies ◽

Cancer Patients ◽

First Line ◽

First Line Therapy ◽

Line Therapy ◽

Abstract 2619: Genetic landscape of KRAS-NRAS-BRAF-PIK3CA wild type metastatic colorectal cancer patients enrolled in the CAPRI clinical trial

10.1158/1538-7445.am2018-2619 ◽

2018 ◽

Author(s):

Anna Maria Rachiglio ◽

Matilde Lambiase ◽

Francesca Fenizia ◽

Alessia Iannaccone ◽

Cristin Roma ◽

...

Keyword(s):

Colorectal Cancer ◽

Clinical Trial ◽

Cancer Patients ◽

Wild Type ◽

Genetic Landscape ◽

FOLFIRI plus panitumumab as second-line treatment in mutated RAS metastatic colorectal cancer patients who converted to wild type RAS after receiving first-line FOLFOX/CAPOX plus bevacizumab-based treatment: Phase II CONVERTIX trial

Annals of Oncology ◽

10.1093/annonc/mdz155.088 ◽

2019 ◽

Vol 30 ◽

pp. iv23-iv24 ◽

Cited By ~ 3

Author(s):

A. Fernández Montes ◽

N. Martinez Lago ◽

J. De la Cámara Gómez ◽

M. Covela Rúa ◽

A. Cousillas Castiñeiras ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Phase Ii ◽

Treatment Phase ◽

Line Treatment ◽

Second Line ◽

Wild Type ◽

First Line ◽

A phase 2 study of panitumumab with irinotecan as salvage therapy in chemorefractory KRAS exon 2 wild-type metastatic colorectal cancer patients

British Journal of Cancer ◽

10.1038/s41416-019-0537-z ◽

2019 ◽

Vol 121 (5) ◽

pp. 378-383 ◽

Author(s):

Elena Elez ◽

Carles Pericay ◽

Manuel Valladares-Ayerbes ◽

Inmaculada Bando ◽

Maria Jose Safont ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Salvage Therapy ◽

Phase 2 ◽

Wild Type ◽

Exon 2 ◽

Phase 2 Study ◽

Colorectal Cancer Patients ◽

Kras Exon

CMAB009 plus irinotecan versus irinotecan-only as second-line treatment after fluoropyrimidine and oxaliplatin failure in KRAS wild-type metastatic colorectal cancer patients: promising findings from a prospective, open-label, randomized, phase III trial

Cancer Communications ◽

10.1186/s40880-019-0374-8 ◽

2019 ◽

Vol 39 (1) ◽

pp. 28 ◽

Author(s):

Yuankai Shi ◽

Jin Li ◽

Jianming Xu ◽

Yan Sun ◽

Liwei Wang ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Phase Iii ◽

Line Treatment ◽

Second Line ◽

Wild Type ◽

Open Label ◽

Phase Iii Trial ◽

397O Avelumab plus cetuximab in pre-treated RAS wild type metastatic colorectal cancer patients as a rechallenge strategy: The phase II CAVE (cetuximab-avelumab) mCRC study

Annals of Oncology ◽

10.1016/j.annonc.2020.08.508 ◽

2020 ◽

Vol 31 ◽

pp. S409-S410

Author(s):

E. Martinelli ◽

G. Martini ◽

T. Troiani ◽

F. Pietrantonio ◽

A. Avallone ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Phase Ii ◽

Wild Type ◽

P-78 Early tumour shrinkage, depth of response and survival outcomes for RAS wild-type metastatic colorectal cancer patients classified by baseline tumour load: Retrospective pooled analysis of panitumumab PRIME/PEAK studies

Annals of Oncology ◽

10.1016/j.annonc.2020.04.160 ◽

2020 ◽

Vol 31 ◽

pp. S114-S115

Author(s):

F. Loupakis ◽

M. Peeters ◽

M. Geissler ◽

D. Modest ◽

M. Valladares-Ayerbes ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Pooled Analysis ◽

Survival Outcomes ◽

Wild Type ◽

Depth Of Response ◽

Tumour Load ◽

Tumour Shrinkage ◽

Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens

Cancer Biology & Therapy ◽

10.4161/cbt.26343 ◽

2013 ◽

Vol 14 (12) ◽

pp. 1098-1103 ◽

Cited By ~ 18

Author(s):

Filippo Pietrantonio ◽

Federica Perrone ◽

Pamela Biondani ◽

Claudia Maggi ◽

Andrea Lampis ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Single Agent ◽

Wild Type ◽

EGFR Fluorescence In situ Hybridization Pattern of Chromosome 7 Disomy Predicts Resistance to Cetuximab in KRAS Wild-type Metastatic Colorectal Cancer Patients

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-10-0208 ◽

2010 ◽

Vol 17 (2) ◽

pp. 382-390 ◽

Cited By ~ 18

Author(s):

Yu-Hong Li ◽

Fang Wang ◽

Lin Shen ◽

Yan-Ming Deng ◽

Qiong Shao ◽

...

Keyword(s):

Colorectal Cancer ◽

In Situ Hybridization ◽

Fluorescence In Situ Hybridization ◽

Cancer Patients ◽

Chromosome 7 ◽

Wild Type ◽

Hybridization Pattern ◽

Intensive first line FIr-C/FOx-C association of triplet chemotherapy plus cetuximab in RAS wild-type metastatic colorectal cancer patients: Preliminary phase II data and individual limiting toxicity syndromes prediction by pharmacogenomic biomarkers

Annals of Oncology ◽

10.1093/annonc/mdy151.205 ◽

2018 ◽

Vol 29 ◽

pp. v57 ◽

Author(s):

G. Bruera ◽

S. Massacese ◽

F. Pepe ◽

U. Malapelle ◽

A. Dal Mas ◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Phase Ii ◽

Wild Type ◽

First Line ◽

Triplet Chemotherapy ◽

Colorectal Cancer Patients ◽

Preliminary Phase