Gamma and UV radiations induced treatment of anti-cancer methotrexate drug in aqueous medium: Effect of process variables on radiation efficiency evaluated using bioassays

Interactive digital tools increasingly used for language learning can provide detailed system logs (e.g., number of attempts, responses submitted), and thereby a window into the user’s learning processes. To date, SLA researchers have made little use of such data to understand the relationships between learning conditions, processes, and outcomes. To fill this gap, we analyzed and interpreted detailed logs from an ICALL system used in a randomized controlled field study where 205 German learners of English in secondary school received either general or specific corrective feedback on grammar exercises. In addition to explicit pre-/post-test results, we derived 19 learning process variables from the system log. Exploratory factor analysis revealed three latent factors underlying these process variables: effort,accuracy focus, and time on task. Accuracy focus and finish time (a process variable that did not load well on any factors) significantly predicted pre-/post-test gain scores with a medium effect size. We then clustered learners based on their process patterns and found that the specific feedback group tended to demonstrate particular learning processes and that these patterns moderate the advantage of specific feedback. We discuss the implications of analyzing system logs for SLA, CALL, and education researchers and call for more collaboration.

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Poly(glycerol sebacate) nanoparticles for encapsulation of hydrophobic anti-cancer drugs

Polymer Chemistry ◽

10.1039/c6py02192a ◽

2017 ◽

Vol 8 (34) ◽

pp. 5033-5038 ◽

Cited By ~ 7

Author(s):

Benoit Louage ◽

Liesa Tack ◽

Yadong Wang ◽

Bruno G. De Geest

Keyword(s):

Aqueous Medium ◽

Therapeutic Efficacy ◽

Pharmacokinetic Profile ◽

Cancer Drugs ◽

High Interest ◽

Hydrophobic Compounds ◽

Anti Cancer

Physical encapsulation of hydrophobic compounds into nanocarriers that are stable in aqueous medium is of high interest as it can increase solubilization of the drug, lower its toxicity, control its pharmacokinetic profile and thus overall improve the therapeutic efficacy.

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Electrocoagulation induced treatment of indigo carmine textile dye in an aqueous medium: the effect of process variables on efficiency evaluated using biochemical response of Gammarus pulex

Environmental Science and Pollution Research ◽

10.1007/s11356-021-14819-0 ◽

2021 ◽

Author(s):

Mehtap Tanyol ◽

Nuran Cikcikoglu Yildirim ◽

Dilek Alparslan

Keyword(s):

Aqueous Medium ◽

Indigo Carmine ◽

Gammarus Pulex ◽

Biochemical Response ◽

Textile Dye ◽

Process Variables

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Mono and Tri-cationic Imidazolium Salts: Use as Stabilizers for Silver Nanoparticles and Anticancer Study

Asian Journal of Organic & Medicinal Chemistry ◽

10.14233/ajomc.2021.ajomc-p331 ◽

2021 ◽

Vol 6 (3) ◽

pp. 167-174

Author(s):

R. Rohini ◽

N. Naresh Reddy ◽

A. Sanjeev ◽

S. Bhaskar ◽

P. Muralidhar Reddy

Keyword(s):

Silver Nanoparticles ◽

Aqueous Medium ◽

Chemical Reduction ◽

Reaction Medium ◽

Morphology Control ◽

Medium Effect ◽

Imidazolium Salts ◽

Size And Morphology ◽

Size And Morphology Control

In present strudy, the synthesis and characterization of monocationic 1,3-tetradecylimidazolium; [(C14)2Im]Br and tricationic benzene centered tris-tetradecyl/hexadecyl imidazolium bromide salts; i.e. [(C14)3C6H3Im]Br3 and [(C16)3C6H3ImBr]Br3 is reported. The stabilizer role of imidazolium salts to prepare silver nanoparticles (AgNPs) via chemical reduction method was investigated. To understand the reaction medium effect on the size and morphology control of AgNPs, monophasic (aqueous medium) and biphasic (DCM/H2O) approaches were applied. The morphology control was noticed for AgNPs protected with [(C14)3C6H3Im]Br3 (show sphere like morphology) and [(C14)2Im]Br (show dendritic structures) via biphasic approach. A clear variation in the size and morphology of AgNPs was noticed by varying the type of stabilizers and reaction medium. It was also observed that AgNPs were formed and stabilized only in aqueous medium in both approaches, thus it is assumed that AgNPs surfaces were protected by imidazolium salts with bilayer fashion. Anticancer activity of imidazolium salts was performed by MTT assay against HeLa cancer cell lines. The result shows that cytotoxic activity of tricationic [(C14)3C6H3Im]Br3 was more potent than that of monocationic [(C14)2Im]Br. The outcome suggests that there is an urgent need to develop new polycationic imidazolium salts for various chemical and medicinal applications.

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