Reflections on the Implementation of Low-dose Computed Tomography Screening in Individuals at High Risk of Lung Cancer in Spain

2017 ◽  
Vol 53 (10) ◽  
pp. 568-573
Author(s):  
Pilar Garrido ◽  
Marcelo Sánchez ◽  
José Belda Sanchis ◽  
Nicolás Moreno Mata ◽  
Ángel Artal ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
High Risk ◽  
Low Dose ◽  
Low Dose Computed Tomography

Cost-effectiveness analysis of lung cancer screening with low-dose computed tomography in an Iranian high-risk population

2021 ◽  
pp. 096914132110182
Author(s):  
Mansur Haji Esmaeili ◽  
Farshad Seyednejad ◽  
Alireza Mahboub-Ahari ◽  
Hossein Ameri ◽  
Hadi Abdollahzad ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Cost Effectiveness ◽  
High Risk ◽  
Low Dose ◽  
High Risk Population ◽  
Risk Population ◽  
System Perspective ◽  
The Cost ◽  
Low Dose Computed Tomography

Objective The results of recent studies have shown that using low-dose computed tomography (LDCT) for screening of lung cancer (LC) improves cancer outcomes. The objective of the current study was to evaluate the cost-effectiveness of LDCT in an Iranian high-risk population. Methods A Markov cohort simulation model with four health states was used to evaluate the cost-effectiveness of LDCT from a healthcare system perspective in the people aged 55–74 who smoked 25 or more cigarettes per day for 10–30 years. Cost data were collected, reviewing 324 medical records of patients with LC, and utilities and transition probabilities were extracted from the literature. The Monte Carlo simulation method was applied to run the model. Probabilistic sensitivity analysis and one-way analysis were also performed. Results LC screening in comparison to a no-screening strategy was costly and effective. The incremental cost-effectiveness ratio of screening versus no-screening was IRR (Iranian rials) 98,515,014.04 which falls below the Iranian threshold of three times GDP (gross domestic product) per capita. One-way and probabilistic sensitivity analyses demonstrated that the results of the economic analysis were robust to variations in the key inputs for both. Conclusions Using LDCT for screening of LC patients in a high-risk population is a cost-effective strategy.

scholarly journals Estimating the Cost-Effectiveness of Lung Cancer Screening with Low-Dose Computed Tomography for High-Risk Smokers in Australia

2018 ◽  
Vol 13 (8) ◽  
pp. 1094-1105 ◽  
Author(s):  
Stephen Wade ◽  
Marianne Weber ◽  
Michael Caruana ◽  
Yoon-Jung Kang ◽  
Henry Marshall ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Cost Effectiveness ◽  
Cancer Screening ◽  
High Risk ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
The Cost ◽  
Low Dose Computed Tomography
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