scholarly journals Hemostatic resuscitation for massive hemorrhage with warm fresh whole blood in a patient with severe blunt trauma

2014 ◽  
Vol 37 (4) ◽  
pp. 205-207 ◽  
Author(s):  
Yuan-Hao Liu ◽  
Chia-Sheng Chao ◽  
Yee-Phoung Chang ◽  
Hsien-Kuo Chin
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Tanya Anand ◽  
Omar Obaid ◽  
Adam Nelson ◽  
Mohamad Chehab ◽  
Michael Ditillo ◽  
...  

2021 ◽  
Vol 52 (2) ◽  
pp. e4004801
Author(s):  
Laureano Quintero ◽  
Juan Jose Melendez-Lugo ◽  
Helmer Emilio Palacios-Rodríguez ◽  
Natalia Padilla ◽  
Luis Fernando Pino ◽  
...  

Patients with hemodynamic instability have a sustained systolic blood pressure less or equal to 90 mmHg, a heart rate greater or equal to 120 beats per minute and an acute compromise of the ventilation/oxygenation ratio and/or an altered state of consciousness upon admission. These patients have higher mortality rates due to massive hemorrhage, airway injury and/or impaired ventilation. Damage control resuscitation is a systematic approach that aims to limit physiologic deterioration through a group of strategies that address the physiologic debt of trauma. This article aims to describe the experience earned by the Trauma and Emergency Surgery Group (CTE) of Cali, Colombia in the management of the severely injured trauma patient in the emergency department following the basic principles of damage control surgery. Since bleeding is the main cause of death, the management of the severely injured trauma patient in the emergency department requires a multidisciplinary team, which should perform damage control maneuvers aimed at rapidly control bleeding, hemostatic resuscitation and/or prompt transfer to the operating room, if required.


2021 ◽  
Vol 8 ◽  
Author(s):  
Thomas H. Edwards ◽  
Anthony E. Pusateri ◽  
Erin Long Mays ◽  
James A. Bynum ◽  
Andrew P. Cap

Since the inception of recent conflicts in Afghanistan and Iraq, transfusion practices in human military medicine have advanced considerably. Today, US military physicians recognize the need to replace the functionality of lost blood in traumatic hemorrhagic shock and whole blood is now the trauma resuscitation product of choice on the battlefield. Building on wartime experiences, military medicine is now one of the country's strongest advocates for the principle of hemostatic resuscitation using whole blood or balanced blood components as the primary means of resuscitation as early as possibly following severe trauma. Based on strong evidence to support this practice in human combat casualties and in civilian trauma care, military veterinarians strive to practice similar hemostatic resuscitation for injured Military Working Dogs. To this end, canine whole blood has become increasingly available in forward environments, and non-traditional storage options for canine blood and blood components are being explored for use in canine trauma. Blood products with improved shelf-life and ease of use are not only useful for military applications, but may also enable civilian general and specialty practices to more easily incorporate hemostatic resuscitation approaches to canine trauma care.


Transfusion ◽  
2016 ◽  
Vol 56 ◽  
pp. S190-S202 ◽  
Author(s):  
Philip C. Spinella ◽  
Heather F. Pidcoke ◽  
Geir Strandenes ◽  
Tor Hervig ◽  
Andrew Fisher ◽  
...  

2020 ◽  
Vol 40 (04) ◽  
pp. 515-523
Author(s):  
Emmanuelle Scala ◽  
Carlo Marcucci

AbstractViscoelastic whole blood tests are increasingly used to guide hemostatic therapy in bleeding patients in the perioperative, trauma, and obstetric settings. Compared with standard laboratory tests of hemostasis, they have a shorter turnaround time and provide simultaneous information on various aspects of clot formation and lysis. The two available brands TEG (thromboelastography) and ROTEM (rotational thromboelastometry) provide devices that are either manually operated or fully automated. The automation allows for the assays to be used as point-of-care tests increasing their usefulness in massively bleeding patients with rapidly changing hemostatic profiles. While the number of research papers on the subject and the number of published treatment algorithms increase rapidly, the influence of the use of these devices on patient outcome needs yet to be established. In this article, we first review the technology of these devices and the parameters provided by the assays. Next, we present the problems encountered when choosing cut-off values that trigger intervention. Furthermore, we discuss the studies examining their influence on clinical outcomes, and finally, we briefly highlight some of the most important limitations and pitfalls inherent to these assays.


2020 ◽  
Vol 89 (2) ◽  
pp. 329-335 ◽  
Author(s):  
Kamil Hanna ◽  
Letitia Bible ◽  
Mohamad Chehab ◽  
Samer Asmar ◽  
Molly Douglas ◽  
...  

2015 ◽  
Vol 42 (4) ◽  
pp. 273-278 ◽  
Author(s):  
MAURICIO GODINHO ◽  
PEDRO PADIM ◽  
PAULO ROBERTO B. EVORA ◽  
SANDRO SCARPELINI

Trauma is one of the world's leading causes of death within the first 40 years of life and thus a significant health problem. Trauma accounts for nearly a third of the lost years of productive life before 65 years of age and is associated with infection, hemorrhagic shock, reperfusion syndrome, and inflammation. The control of hemorrhage, coagulopathy, optimal use of blood products, balancing hypo and hyperperfusion, and hemostatic resuscitation improve survival in cases of trauma with massive hemorrhage. This review discusses inflammation in the context of trauma-associated hemorrhagic shock. When one considers the known immunomodulatory effects of traumatic injury, allogeneic blood transfusion, and the overlap between patient populations, it is surprising that so few studies have assessed their combined effects on immune function. We also discuss the relative benefits of curbing inflammation rather than attempting to prevent it.


Trauma ◽  
2021 ◽  
pp. 146040862110195
Author(s):  
Nilesh Y Jagne ◽  
Ruby Kataria ◽  
Bhaskar Sarkar ◽  
Amulya Rattan

Background: Penetrating injuries to sacrum are rare; only a few reports have been published in literature. We hereby report the first case of low velocity penetrating trauma leading to coccygeal fracture dislocation and exsanguination, without any major abdominal/vascular injury. Case Report: The patient underwent wound packing bedside and hemostatic resuscitation. Wound packing was successful in achieving hemostasis. He stabilized after 1.5 L of fluids, massive hemorrhage protocol institution (12-unit blood components), and vasopressor support. The presentation is unique and not reported in literature published so far. Conclusion: This report is a pertinent example of lifesaving potential of effective wound packing, which is often under-utilized. Possibility of associated neurological injury and residual foreign bodies is there in such cases. They should be duly assessed after stabilizing life-threatening injuries.


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