Influence of low-dose and low-dose-rate ionizing radiation on mutation induction in human cells

2007 ◽  
Vol 40 (4) ◽  
pp. 470-473
Author(s):  
F. Yatagai ◽  
Y. Umebayashi ◽  
M. Suzuki ◽  
T. Abe ◽  
H. Suzuki ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Dose Rate ◽  
Low Dose ◽  
Human Cells ◽  
Mutation Induction ◽  
Low Dose Rate

scholarly journals Mutation Induction in Cultured Human Cells after Low-dose and Low-dose-rate γ-ray Irradiation: Detection by LOH Analysis

2007 ◽  
Vol 48 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Yukihiro UMEBAYASHI ◽  
Masamitsu HONMA ◽  
Masao SUZUKI ◽  
Hiromi SUZUKI ◽  
Toru SHIMAZU ◽  
...  
Keyword(s):  
Dose Rate ◽  
Low Dose ◽  
Human Cells ◽  
Mutation Induction ◽  
Irradiation Detection ◽  
Low Dose Rate ◽  
Cultured Human Cells ◽  
Γ Ray

Using a Temperature-Switching Approach to Evaluate Low-Dose-Rate Ionizing Radiation Effects on SET in Linear Bipolar Circuits

2019 ◽  
Vol 66 (7) ◽  
pp. 1557-1565 ◽  
Author(s):  
Shuai Yao ◽  
Wu Lu ◽  
Xin Yu ◽  
Qi Guo ◽  
Chengfa He ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Dose Rate ◽  
Radiation Effects ◽  
Low Dose ◽  
Low Dose Rate

scholarly journals The Effects of Low Dose-Rate Ionizing Radiation on the Shapes of Transients in the L>M124 Operational Amplifier

2008 ◽  
Vol 55 (6) ◽  
pp. 3314-3320 ◽  
Author(s):  
Stephen Buchner ◽  
Dale McMorrow ◽  
Nicholas Roche ◽  
Laurent Dusseau ◽  
Ron L. Pease
Keyword(s):  
Ionizing Radiation ◽  
Dose Rate ◽  
Operational Amplifier ◽  
Low Dose ◽  
Low Dose Rate

scholarly journals Increased Frequency of Copy Number Variations Revealed by Array Comparative Genomic Hybridization in the Offspring of Male Mice Exposed to Low Dose-Rate Ionizing Radiation

2021 ◽  
Vol 22 (22) ◽  
pp. 12437
Author(s):  
Keiji Ogura ◽  
Yoshiko Ayabe ◽  
Chihiro Harada ◽  
Ignacia Braga Tanaka ◽  
Satoshi Tanaka ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Dose Rate ◽  
Copy Number ◽  
Array Comparative Genomic Hybridization ◽  
Low Dose ◽  
De Novo ◽  
Copy Number Variations ◽  
Comparative Genomic ◽  
Male Mice ◽  
Low Dose Rate

There is very little information on the transgenerational or genetic effects of low dose-rate ionizing radiation. We report the detection of the transgenerational effects of chronic low dose-rate irradiation in mice, at the molecular level in the whole genome, using array comparative genomic hybridization technology. We observed that the number of the mice with de novo copy number variations (specifically, deletions) was significantly increased in the offspring of C57BL/6J male mice exposed to 20 mGy/day gamma-rays for 400 days (total dose: 8000 mGy), as compared to non-irradiated controls. We did not detect any difference in the size of the de novo deletions between the irradiated and the non-irradiated groups. An analysis of the life span of the offspring suggested a possibility that de novo copy-number variations may be associated with shorter life spans.

Effects of a very low dose rate of chronic ionizing radiation on the division potential of human embryonic lung fibroblasts in vitro

1986 ◽  
Vol 21 (1) ◽  
pp. 1-11 ◽  
Author(s):  
F. Croute ◽  
S. Vidal ◽  
J.P. Soleilhavoup ◽  
C. Vincent ◽  
G. Serre ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Dose Rate ◽  
Low Dose ◽  
Lung Fibroblasts ◽  
Embryonic Lung ◽  
Human Embryonic Lung ◽  
Low Dose Rate
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