Clinical crosstalk between coronary and carotid arterial territories

2021 ◽  
Vol 331 ◽  
pp. e283-e284
Author(s):  
J.P. Sousa ◽  
L. Puga ◽  
C. Lourenco ◽  
L. Gonçalves
Keyword(s):  
Carotid Arterial

Systemic Effects of ADP-induced Platelet Aggregation and Their Modification by Aspirin and by Pyridinolcarbamate

1973 ◽  
Vol 30 (01) ◽  
pp. 178-190 ◽  
Author(s):  
Itsuro Kobayashi ◽  
Paul Didisheim
Keyword(s):  
Platelet Aggregation ◽  
Venous Pressure ◽  
Systemic Effects ◽  
Central Venous ◽  
Platelet Aggregates ◽  
Induced Changes ◽  
Second Wave ◽  
Carotid Arterial ◽  
Arterial Po2

SummaryADP, AMP, or ATP was injected rapidly intravenously in rats. ADP injection resulted in the f olio wing transient changes: a drop in platelet count, a rise in central venous pressure, a fall in carotid arterial PO2, bradycardia, arrhythmia, flutter-fibrillation, and arterial hypotension. AMP and ATP produced some of these same effects; but except for hypotension, their frequency and severity Avere much less than those following ADP.Prior intravenous administration of acetylsalicylic acid or pyridinolcarbamate, two inhibitors of the second wave of ADP-induced platelet aggregation in vitro, significantly reduced the frequency and severity of all the above ADP-induced changes except hypotension. These observations suggest that many of the changes (except hypotension) observed to follow ADP injection are produced by platelet aggregates which lodge transiently in various microcirculatory beds then rapidly disaggregate and recirculate.

Platelet Hyperaggregability in Ischemic Cerebrovascular Disease and Effects of Aspirin

1982 ◽  
Vol 48 (02) ◽  
pp. 117-119 ◽  
Author(s):  
M Kusunoki ◽  
K Kimura ◽  
K Nagatsuka ◽  
Y Isaka ◽  
O Uyama ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Venous Blood ◽  
Second Phase ◽  
Cerebral Angiogram ◽  
Peripheral Venous Blood ◽  
Chronic Stage ◽  
Ischemic Cerebrovascular Disease ◽  
Carotid Arterial ◽  
Platelet Hyperaggregability ◽  
The Brain

SummaryPlatelet aggregation was studied in 24 patients in the chronic stage of ischemic cerebrovascular disease (CVD), with cerebral affluent and effluent blood, i.e., carotid arterial and internal jugular venous blood, and also with peripheral venous blood. Aggregation tests were performed at various final concentrations of sodium arachidonate (A.A.) and ADP. In 17 patients, not taking aspirin, platelet aggregability in jugular venous blood was significantly accentuated compared with that in arterial and peripheral venous blood. This tendency was more marked in the patients with cerebral artery stenosis and/or occlusion than in those with normal cerebral angiogram. In 7 patients taking 500 mg or more oral aspirin, aggregation differences across the brain were not observed and A.A. aggregation and the second phase of ADP aggregation were completely suppressed. These results suggest that a prophylactic administration of aspirin may be beneficial for patients in chronic stage of CVD.

Circadian blood pressure and heart rate rhythms in mice

1999 ◽  
Vol 276 (2) ◽  
pp. R500-R504 ◽  
Author(s):  
Ping Li ◽  
Steven H. Sur ◽  
Ralph E. Mistlberger ◽  
Mariana Morris
Keyword(s):  
Heart Rate ◽  
Sampling Rate ◽  
Eating Patterns ◽  
Cardiovascular Parameters ◽  
C57bl Mice ◽  
Weight Analysis ◽  
Using Data ◽  
Computerized Monitoring ◽  
Carotid Arterial ◽  
Mean Heart Rate

The circadian pattern of mean arterial pressure (MAP) and heart rate (HR) was measured in C57BL mice with carotid arterial catheters. Cardiovascular parameters were recorded continuously with a computerized monitoring system at a sampling rate of 100 Hz. The tethered animals were healthy, showing stabilized drinking and eating patterns within 2 days of surgery and little loss of body weight. Analysis of the 24-h pattern of MAP and HR was conducted using data from 3–6 consecutive days of recording. A daily rhythm of MAP was evident in all mice, with group mean dark and light values of 101.4 ± 7.3 and 93.1 ± 2.9 mmHg, respectively. The group mean waveform was bimodal, with peak values evident early and late in the dark period, and a trough during the middle of the light period. The phase of maximum and minimum values showed low within-group variance. Mean heart rate was greater at night than during the day (561.9 ± 22.7 vs. 530.3 ± 22.3 beats/min). Peak values generally occurred at dark onset, and minimum values during the middle of both the dark and the light periods. We conclude that it is possible to perform measurements of circadian cardiovascular parameters in the mouse, providing new avenues for the investigation of genetic models.

Bilateral Internal Carotid Arterial Occlusions Associated With Fibromuscular Dysplasia

1979 ◽  
Vol 13 (5) ◽  
pp. 349-352 ◽  
Author(s):  
Charles A. Andersen ◽  
George J. Collins ◽  
Norman M. Rich ◽  
Paul T. Mcdonald
Keyword(s):  
Fibromuscular Dysplasia ◽  
Internal Carotid ◽  
Carotid Arterial

Management of penetrating carotid arterial injury

1979 ◽  
Vol 19 (9) ◽  
pp. 713
Author(s):  
Liekweg ◽  
Greenfield ◽  
Ernest E. Moore
Keyword(s):  
Arterial Injury ◽  
Carotid Arterial
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