Clinical Validation of the Canada Lymph Node Score for Endobronchial Ultrasound

A 27-year-old man was diagnosed with inflammatory myofibroblastic tumor, and multiple lymph node and subcutaneous metastases. After several administrations of anti-tumor therapy, he underwent mediastinal lymph node biopsy using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) to confirm tumor relapse. Five weeks later, he complained of chest pain, then rapidly developed shock due to acute pericarditis. Although he was treated with antibiotics for anaerobic bacterial infection and cardiac drainage, mediastinal lymph node abscess and pericarditis did not improve. After the surgical procedure, his physical condition dramatically improved and he was treated with another molecularly targeted therapy. Pericarditis associated with EBUS-TBNA is extremely rare. In this case, salvage was achieved by surgical drainage of the lymph node abscess and pericarditis, and long survival was obtained with further administration of anti-tumor treatment.

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Endobronchial ultrasound-guided transbronchial needle biopsy for the diagnosis of intrathoracic lymph node metastases from extrathoracic malignancies: A meta-analysis and systematic review

Respirology ◽

10.1111/resp.12335 ◽

2014 ◽

Vol 19 (6) ◽

pp. 834-841 ◽

Cited By ~ 20

Author(s):

Bo Yang ◽

Fang Li ◽

Weiwei Shi ◽

Hui Liu ◽

Shengjie Sun ◽

...

Keyword(s):

Systematic Review ◽

Lymph Node ◽

Lymph Node Metastases ◽

Needle Biopsy ◽

Meta Analysis ◽

Endobronchial Ultrasound ◽

Ultrasound Guided ◽

Node Metastases

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Endobronchial Ultrasound Node Characteristics In Evaluation Of Lymph Node Metastasis: A Prospective Study

10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2986 ◽

2012 ◽

Author(s):

Ben Bregman ◽

Christina Bellinger

Keyword(s):

Lymph Node ◽

Lymph Node Metastasis ◽

Prospective Study ◽

Endobronchial Ultrasound ◽

Node Metastasis ◽

A Prospective Study

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Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer staging: early experience in Brazil,

Jornal Brasileiro de Pneumologia ◽

10.1590/s1806-37132015000100004 ◽

2015 ◽

Vol 41 (1) ◽

pp. 23-30 ◽

Cited By ~ 5

Author(s):

Viviane Rossi Figueiredo ◽

Paulo Francisco Guerreiro Cardoso ◽

Márcia Jacomelli ◽

Sérgio Eduardo Demarzo ◽

Addy Lidvina Mejia Palomino ◽

...

Keyword(s):

Lung Cancer ◽

Lymph Node ◽

Lymph Nodes ◽

Cancer Staging ◽

Accurate Method ◽

Needle Aspiration ◽

Endobronchial Ultrasound ◽

Lymph Node Staging ◽

Ultrasound Guided ◽

Transbronchial Needle Aspiration

Objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive, safe and accurate method for collecting samples from mediastinal and hilar lymph nodes. This study focused on the initial results obtained with EBUS-TBNA for lung cancer and lymph node staging at three teaching hospitals in Brazil. Methods: This was a retrospective analysis of patients diagnosed with lung cancer and submitted to EBUS-TBNA for mediastinal lymph node staging. The EBUS-TBNA procedures, which involved the use of an EBUS scope, an ultrasound processor, and a compatible, disposable 22 G needle, were performed while the patients were under general anesthesia. Results: Between January of 2011 and January of 2014, 149 patients underwent EBUS-TBNA for lymph node staging. The mean age was 66 ± 12 years, and 58% were male. A total of 407 lymph nodes were sampled by EBUS-TBNA. The most common types of lung neoplasm were adenocarcinoma (in 67%) and squamous cell carcinoma (in 24%). For lung cancer staging, EBUS-TBNA was found to have a sensitivity of 96%, a specificity of 100%, and a negative predictive value of 85%. Conclusions: We found EBUS-TBNA to be a safe and accurate method for lymph node staging in lung cancer patients.

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