Identification and characterization of a unique leucine-rich repeat protein (LRRC33) that inhibits Toll-like receptor-mediated NF-κB activation

2013 ◽  
Vol 434 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Jingyi Liu ◽  
Zhujun Zhang ◽  
Limin Chai ◽  
Yongzhe Che ◽  
Siping Min ◽  
...  
Keyword(s):  
Leucine Rich Repeat ◽  
Toll Like Receptor ◽  
Repeat Protein ◽  
Identification And Characterization ◽  
Leucine Rich Repeat Protein

scholarly journals Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family

FEBS Letters ◽  
2004 ◽  
Vol 563 (1-3) ◽  
pp. 69-74 ◽  
Author(s):  
Ryoko Shimizu-Hirota ◽  
Hiroyuki Sasamura ◽  
Mari Kuroda ◽  
Emi Kobayashi ◽  
Takao Saruta
Keyword(s):  
Functional Characterization ◽  
Protein Family ◽  
Leucine Rich Repeat ◽  
Repeat Protein ◽  
New Class ◽  
Leucine Rich Repeat Protein

scholarly journals Characterization of a novel anther-specific gene encoding a leucine-rich repeat protein in petunia

2014 ◽  
Vol 13 (4) ◽  
pp. 9889-9898 ◽  
Author(s):  
Y.Z. Yue ◽  
J. Sun ◽  
X. Huang ◽  
H. Peng ◽  
G.F. Liu ◽  
...  
Keyword(s):  
Specific Gene ◽  
Leucine Rich Repeat ◽  
Gene Encoding ◽  
Repeat Protein ◽  
Leucine Rich Repeat Protein

scholarly journals Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5)

2012 ◽  
Vol 287 (10) ◽  
pp. 7357-7365 ◽  
Author(s):  
Joel W. Thompson ◽  
Ameen A. Salahudeen ◽  
Srinivas Chollangi ◽  
Julio C. Ruiz ◽  
Chad A. Brautigam ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Leucine Rich Repeat ◽  
Repeat Protein ◽  
Leucine Rich Repeat Protein

In vitro characterization of the cysteine-rich capping domains in a plant leucine rich repeat protein

2006 ◽  
Vol 1764 (6) ◽  
pp. 1043-1053 ◽  
Author(s):  
Olatomirin O. Kolade ◽  
Vicki A. Bamford ◽  
Gema Ancillo Anton ◽  
Jonathan D.G. Jones ◽  
Pablo Vera ◽  
...  
Keyword(s):  
Leucine Rich Repeat ◽  
Repeat Protein ◽  
In Vitro Characterization ◽  
Leucine Rich Repeat Protein

scholarly journals Neuronal Leucine-Rich Repeat Protein 4 Functions in Hippocampus-Dependent Long-Lasting Memory

2005 ◽  
Vol 25 (10) ◽  
pp. 4166-4175 ◽  
Author(s):  
Takayoshi Bando ◽  
Keisuke Sekine ◽  
Shizuka Kobayashi ◽  
Ayako M. Watabe ◽  
Armin Rump ◽  
...  
Keyword(s):  
Type I ◽  
Memory Retention ◽  
Leucine Rich Repeat ◽  
Learning Tasks ◽  
Repeat Proteins ◽  
Neuronal Tissues ◽  
Dependent Learning ◽  
Identification And Characterization ◽  
Leucine Rich Repeat Protein

ABSTRACT Neuronal leucine-rich repeat proteins (NLRRs) are type I transmembrane proteins and expressed in neuronal tissues, but their function remains unknown. Here, we describe the identification and characterization of a new member of the NLRR family, NLRR4, and its potential role in long-lasting memory. We generated NLRR4-deficient (NLRR4−/−) mice and found that they showed impaired memory retention. In hippocampus-dependent learning tasks, NLRR4−/− mice were able to learn and maintain the memories for one day but unable to retain the memories for four days after learning. In contrast, in a hippocampus-independent task, NLRR4−/− mice were able to retain the memory normally for at least seven days. These results suggest that NLRR4 plays a key role in hippocampus-dependent long-lasting memory.

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