Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers

2019 ◽  
Vol 85 ◽  
pp. 399-412 ◽  
Author(s):  
Ahmed M. Sh. El-Sharief ◽  
Yousry A. Ammar ◽  
Amany Belal ◽  
Marwa A.M. Sh. El-Sharief ◽  
Yehia A. Mohamed ◽  
...  
Keyword(s):  
Biological Activity ◽  
Molecular Docking ◽  
Indole Derivatives ◽  
Design Synthesis ◽  
Activity Evaluation

Design, synthesis and biological activity evaluation of novel conjugated sialic acid and pentacyclic triterpene derivatives as anti-influenza entry inhibitors

MedChemComm ◽  
2016 ◽  
Vol 7 (10) ◽  
pp. 1932-1945 ◽  
Author(s):  
Xu Han ◽  
Yongying Shi ◽  
Longlong Si ◽  
Zibo Fan ◽  
Han Wang ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Biological Activity ◽  
Sialic Acid ◽  
Virus Entry ◽  
Pentacyclic Triterpene ◽  
Design Synthesis ◽  
Entry Inhibitors ◽  
Activity Evaluation ◽  
Virus Entry Inhibitors

A total of 24 novel sialic acid–pentacyclic triterpene conjugates were synthesized and evaluated as anti-influenza virus entry inhibitors.

scholarly journals Design, Synthesis, Molecular Docking and Antibacterial Screening of Some Quinolone Compounds

Proceedings ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 2
Author(s):  
Lucia Pintilie ◽  
Constantin Tanase ◽  
Elena Mihai ◽  
Maria Maganu ◽  
Miron Teodor Caproiu
Keyword(s):  
Biological Activity ◽  
Molecular Docking ◽  
Design Synthesis ◽  
Antibacterial Screening ◽  
Antibacterial Spectrum ◽  
Broad Antibacterial Spectrum

Drugs belonging to the quinolone compounds are characterized by a quicker biological activity and a broad antibacterial spectrum [1–4]. [...]

Design, synthesis, and biological activity evaluation of (-)-6-O-desmethylantofine analogues as potent anti-cancer agents

2019 ◽  
Vol 27 (14) ◽  
pp. 3070-3081 ◽  
Author(s):  
Guifang Han ◽  
Lihua Qing ◽  
Meng Wu ◽  
Yuxiang Wang ◽  
Yuxiu Liu ◽  
...  
Keyword(s):  
Biological Activity ◽  
Design Synthesis ◽  
Activity Evaluation ◽  
Anti Cancer

Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2

2019 ◽  
Vol 92 ◽  
pp. 103281 ◽  
Author(s):  
Ramu Manjula ◽  
Nikhila Gokhale ◽  
Sruthi Unni ◽  
Prashant Deshmukh ◽  
Rajkumar Reddyrajula ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Indole Derivatives ◽  
Design Synthesis ◽  
In Vitro Evaluation ◽  
Molecular Docking Studies
Sign in / Sign up

Export Citation Format

Share Document