Role of Ventral Striatal Dopamine D1 Receptor in Cigarette Craving

2007 ◽  
Vol 61 (11) ◽  
pp. 1252-1259 ◽  
Author(s):  
Fumihiko Yasuno ◽  
Miho Ota ◽  
Kiyoshi Ando ◽  
Tomomichi Ando ◽  
Jun Maeda ◽  
...  
Keyword(s):  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Striatal Dopamine ◽  
Cigarette Craving

scholarly journals Role of Aberrant Striatal Dopamine D1 Receptor/cAMP/Protein Kinase A/DARPP32 Signaling in the Paradoxical Calming Effect of Amphetamine

2010 ◽  
Vol 30 (33) ◽  
pp. 11043-11056 ◽  
Author(s):  
F. Napolitano ◽  
A. Bonito-Oliva ◽  
M. Federici ◽  
M. Carta ◽  
F. Errico ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Protein Kinase A ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Striatal Dopamine ◽  
Calming Effect ◽  
Kinase A

Conditional coupling of striatal dopamine D1 receptor to transcription factors: ontogenic and regional differences in CREB activation

1998 ◽  
Vol 60 (1) ◽  
pp. 127-132 ◽  
Author(s):  
Elisabeth Arnauld ◽  
Josette Arsaut ◽  
Jacques Demotes-Mainard
Keyword(s):  
Transcription Factors ◽  
Regional Differences ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Striatal Dopamine ◽  
Creb Activation

scholarly journals Diminished Role of Dopamine D1-Receptor Signaling with the Development of an Addicted Phenotype in Rats

2014 ◽  
Vol 76 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Carolina P. Ramôa ◽  
Susan E. Doyle ◽  
Matthew D. Lycas ◽  
Andrea K. Chernau ◽  
Wendy J. Lynch
Keyword(s):  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Receptor Signaling

P.6.034 Role of dopamine D1 receptor on dopaminergic supersensitivity induced by sleep deprivation in mice

2004 ◽  
Vol 14 ◽  
pp. S371
Author(s):  
C.C. Chinen ◽  
R.R. Faria ◽  
R. Frussa Filho
Keyword(s):  
Sleep Deprivation ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Dopaminergic Supersensitivity

scholarly journals Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors

1997 ◽  
Vol 2 (1) ◽  
pp. 44-56 ◽  
Author(s):  
D E Comings ◽  
R Gade ◽  
S Wu ◽  
C Chiu ◽  
G Dietz ◽  
...  
Keyword(s):  
Potential Role ◽  
Receptor Gene ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Addictive Behaviors

Possible role of the dopamine D1 receptor in the sensorimotor gating deficits induced by high-fat diet

2015 ◽  
Vol 232 (24) ◽  
pp. 4393-4400 ◽  
Author(s):  
Chisato Wakabayashi ◽  
Tadahiro Numakawa ◽  
Yoshiko Ooshima ◽  
Kotaro Hattori ◽  
Hiroshi Kunugi
Keyword(s):  
High Fat Diet ◽  
Sensorimotor Gating ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
High Fat

Positive emotional arousal increases duration of memory traces: Different role of dopamine D1 receptor and β-adrenoceptor activation

2014 ◽  
Vol 122 ◽  
pp. 158-163 ◽  
Author(s):  
D. Conversi ◽  
F. Cruciani ◽  
A. Accoto ◽  
S. Cabib
Keyword(s):  
Emotional Arousal ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Memory Traces

Abstract P337: Angiotensin 1-7 Mitigates Oxidative Stress, Protects Renal Dopamine D1 Receptor Function and Prevents Development of Hypertension

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Mustafa Lokhandwala ◽  
Andrea Diaz Diaz ◽  
Anees Ahamd Banday
Keyword(s):  
Oxidative Stress ◽  
Buthionine Sulfoximine ◽  
Chronic Administration ◽  
Dopamine D1 Receptor ◽  
D1 Receptor ◽  
Sodium Reabsorption ◽  
Sodium Regulation ◽  
Renal Dopamine ◽  
Renal Sodium Reabsorption

The role of angiotensin in etiology of cardiovascular diseases especially in hypertension is well established. Renin-angiotensin-aldosterone contributes to the development and maintenance of hypertension directly by increases in vascular tone and renal sodium reabsorption or indirectly by increasing oxidative stress and inflammation. Contrary to this pathological arm, angiotensin (Ang) 1-7 via Mas receptors has been reported to protect the cardiovascular function although the exact mechanism is not yet clear. We have previously shown that oxidative stress leads to renal dopamine D1 receptor (D1R) dysfunction which could disrupt sodium regulation and subsequently lead to hypertension. In here we wanted to test whether chronic administration of Ang 1-7 in mice could mitigate oxidative stress, protect renal D1R function and prevent development of hypertension. Mice (C57BL) were implanted with telemetry probes and concomitantly treated with L-buthionine sulfoximine (BSO, in drinking water) and Ang 1-7 (via jugular vein by osmotic pumps). Control (C, no treatment) and shams (implanted with saline filled pumps) exhibited similar behavioral and physiological parameters. Mice treated with BSO alone exhibited increased oxidative stress and high BP as compared to controls. Ang 1-7 treatment did not affect oxidative stress and BP in control mice but prevented the increase in BP and oxidative milieu in BSO treated mice. Mean arterial pressure (mmHg), C: 78.5 ± 2.3*; BSO: 97.3 ± 3.8; Ang 1-7: 80.1* ± 4.1; BSO+Ang 1-7: 83.2 ± 3.4*, *P <0.05 vs BSO. SKF38393, a D1R agonist, increased urine and sodium excretion in control mice but failed to induce diuresis or natriuresis in BSO-treated mice. Treatment with Ang 1-7 protected D1R function as both natriuresis and diuresis was observed in mice treated with BSO plus Ang 1-7. Chronic Ang 1-7 had no effect on D1R function in the absence of BSO. These data show that oxidative stress leads to hypertension by disrupting renal D1R dependent sodium regulation. Ang 1-7 mitigates oxidative stress, protects renal D1R function and prevents increase in BP. This study provides a new insight on how beneficial arm of Ang system could protect renal D1R-mediated sodium regulation and prevent development of hypertension during oxidative stress.

Role of the substantia nigra in the expression of dopamine D1 receptor-mediated and D2 receptor-mediated behaviours

Neuroscience ◽  
1987 ◽  
Vol 23 (3) ◽  
pp. 1001-1010 ◽  
Author(s):  
G.H. Fletcher ◽  
M.S. Starr
Keyword(s):  
Substantia Nigra ◽  
D2 Receptor ◽  
Dopamine D1 Receptor ◽  
D1 Receptor
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