A new fluorescent probe with a large turn-on signal for imaging nitroreductase in tumor cells and tissues by two-photon microscopy

2017 ◽  
Vol 89 ◽  
pp. 853-858 ◽  
Author(s):  
Zhan-Rong Liu ◽  
Yonghe Tang ◽  
An Xu ◽  
Weiying Lin
Keyword(s):  
Tumor Cells ◽  
Fluorescent Probe ◽  
Two Photon Microscopy ◽  
Two Photon ◽  
Turn On

A cyanine-derived “turn-on” fluorescent probe for imaging nitroreductase in hypoxic tumor cells

2015 ◽  
Vol 7 (24) ◽  
pp. 10125-10128 ◽  
Author(s):  
Cong Xue ◽  
Yingjie Lei ◽  
Sichun Zhang ◽  
Yaowu Sha
Keyword(s):  
Tumor Cells ◽  
Fluorescent Probe ◽  
Phenol Group ◽  
Turn On ◽  
Hypoxic Tumor

A new “turn-on” fluorescent probe, composed of a protected phenol group with ap-nitrobenzyl moiety that functions as a latent donor and conjugated with two benzo[f]indolinium acceptors, was developed and applied for imaging nitroreductase (NTR) in hypoxic tumor cells.

A two-photon fluorescent probe for selective methylglyoxal detection and application in living cells

2015 ◽  
Vol 7 (6) ◽  
pp. 2386-2390 ◽  
Author(s):  
Tun Tang ◽  
Yimin Zhou ◽  
Yuqi Chen ◽  
Mengjun Li ◽  
Yan Feng ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Two Photon ◽  
Turn On

A novel two-photon fluorescent “turn-on” probe could detect methylglyoxal levels in living cells conveniently.

scholarly journals Chromis-1, a Ratiometric Fluorescent Probe Optimized for Two-Photon Microscopy Reveals Dynamic Changes in Labile Zn(II) in Differentiating Oligodendrocytes

ACS Sensors ◽  
2018 ◽  
Vol 3 (2) ◽  
pp. 458-467 ◽  
Author(s):  
Daisy Bourassa ◽  
Christopher M. Elitt ◽  
Adam M. McCallum ◽  
S. Sumalekshmy ◽  
Reagan L. McRae ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Dynamic Changes ◽  
Two Photon Microscopy ◽  
Two Photon ◽  
Ratiometric Fluorescent Probe

A two-photon fluorescent probe for turn-on monitoring HOCl level in endoplasmic reticulum

2020 ◽  
Vol 180 ◽  
pp. 108435 ◽  
Author(s):  
Tingting Yang ◽  
Junyong Sun ◽  
Wu Yao ◽  
Feng Gao
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Two Photon ◽  
Turn On

Imaging nucleus viscosity and G-quadruplex DNA in living cells using a nucleus-targeting two-photon fluorescent probe

The Analyst ◽  
2018 ◽  
Vol 143 (23) ◽  
pp. 5799-5804 ◽  
Author(s):  
Wan Sun ◽  
Jing-Xue Cui ◽  
Le-Le Ma ◽  
Zhong-Lin Lu ◽  
Bing Gong ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Dna Detection ◽  
Living Cells ◽  
Cell Nuclei ◽  
Quadruplex Dna ◽  
Two Photon ◽  
Turn On ◽  
G Quadruplex

TP-2Bz, as a nucleus targeting “D–π–A” molecule, was developed as a two-photon turn-on fluorescent probe for the viscosity and GQ DNA detection in cell nuclei.

A fast-response two-photon fluorescent probe for the detection of Cys over GSH/Hcy with a large turn-on signal and its application in living tissues

2017 ◽  
Vol 5 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Jian-Yong Wang ◽  
Zhan-Rong Liu ◽  
Mingguang Ren ◽  
Xiuqi Kong ◽  
Weiying Lin
Keyword(s):  
Fluorescent Probe ◽  
Fast Response ◽  
Living Cells ◽  
Two Photon ◽  
Turn On ◽  
Living Tissues

We developed a novel two-photon fluorescent probe for sensing Cys specifically. The two-photon fluorescent probe exhibited favorable properties and was successfully applied for imaging Cys in living cells and tissues.

A rapid response “Turn-On” fluorescent probe for nitroreductase detection and its application in hypoxic tumor cell imaging

The Analyst ◽  
2015 ◽  
Vol 140 (2) ◽  
pp. 574-581 ◽  
Author(s):  
Jian Xu ◽  
Shaobo Sun ◽  
Qian Li ◽  
Ying Yue ◽  
Yingdong Li ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Fluorescent Probe ◽  
Cell Imaging ◽  
Rapid Response ◽  
Indirect Detection ◽  
Turn On ◽  
Hypoxic Tumor

A novel “Turn-On” fluorescent probe, quaternarized 4-pyridinyl-substituted BODIPY dye by incorporating a 5-nitrofuran moiety, was developed and applied for imaging the hypoxic status of tumor cells by the indirect detection of nitroreductase.

833 IMAGING OF NITRIC OXIDE DIRECTLY IN CELLS AND ARTERIES WITH A COPPER (II) FLUORESCENT PROBE AND TWO-PHOTON MICROSCOPY

2011 ◽  
Vol 12 (1) ◽  
pp. 175
Author(s):  
M. Ghosh ◽  
N.M.S.V.D. Akker ◽  
C. Weber ◽  
D.G.M. Molin ◽  
M.A.M.J.V. Zandvoort
Keyword(s):  
Nitric Oxide ◽  
Fluorescent Probe ◽  
Two Photon Microscopy ◽  
Two Photon ◽  
In Cells

scholarly journals A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

RSC Advances ◽  
2018 ◽  
Vol 8 (24) ◽  
pp. 13388-13392 ◽  
Author(s):  
Xiani Chen ◽  
Hang Xu ◽  
Shengnan Ma ◽  
Hongjuan Tong ◽  
Kaiyan Lou ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Michael Addition ◽  
Selective Detection ◽  
Quenching Mechanism ◽  
Two Photon ◽  
Turn On

N-(6-acyl-2-naphthayl)-maleimide (1) is a simple two-photon fluorescent probe with selectivity for cysteine, based on a thiol-Michael-addition-transcyclization cascade and dual PeT/ICT quenching mechanism.

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