Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2008.04.044 ◽

2008 ◽

Vol 18 (12) ◽

pp. 3641-3645 ◽

Author(s):

Scott C. Mayer ◽

Annette L. Banker ◽

Frank Boschelli ◽

Li Di ◽

Mark Johnson ◽

...

Keyword(s):

Growth Factor ◽

Cancer Treatment ◽

Growth Factor Receptor ◽

Insulin Like Growth Factor ◽

Lead Identification ◽

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Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2008.11.037 ◽

2009 ◽

Vol 19 (1) ◽

pp. 62-66 ◽

Author(s):

Lori M. Miller ◽

Scott C. Mayer ◽

Dan M. Berger ◽

Diane H. Boschelli ◽

Frank Boschelli ◽

...

Keyword(s):

Growth Factor ◽

Cancer Treatment ◽

Growth Factor Receptor ◽

Insulin Like Growth Factor ◽

Lead Identification ◽

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ChemInform Abstract: Lead Identification to Generate 3-Cyanoquinoline Inhibitors of Insulin-Like Growth Factor Receptor (IGF-1R) for Potential Use in Cancer Treatment.

10.1002/chin.200920198 ◽

2009 ◽

Vol 40 (20) ◽

Author(s):

Lori M. Miller ◽

et al. et al.

Keyword(s):

Growth Factor ◽

Cancer Treatment ◽

Growth Factor Receptor ◽

Insulin Like Growth Factor ◽

Lead Identification ◽

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Acquired Resistance to Tamoxifen Is Associated with Loss of the Type I Insulin-like Growth Factor Receptor: Implications for Breast Cancer Treatment

Cancer Research ◽

10.1158/0008-5472.can-12-0684 ◽

2012 ◽

Vol 72 (13) ◽

pp. 3372-3380 ◽

Author(s):

Dedra H. Fagan ◽

Ryan R. Uselman ◽

Deepali Sachdev ◽

Douglas Yee

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Cancer Treatment ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Breast Cancer Treatment ◽

Type I ◽

Insulin Like Growth Factor

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Targeting the type 1 insulin-like growth factor receptor as anti-cancer treatment

Anti-Cancer Drugs ◽

10.1097/00001813-200310000-00001 ◽

2003 ◽

pp. 669-682 ◽

Author(s):

Erin A. Bohula ◽

Martin P. Playford ◽

Valentine M. Macaulay

Keyword(s):

Growth Factor ◽

Cancer Treatment ◽

Growth Factor Receptor ◽

Insulin Like Growth Factor ◽

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The insulin-like growth factor receptor is a promising target for innovative treatment approaches of hepatocellular cancer

Zeitschrift für Gastroenterologie ◽

10.1055/s-2005-920140 ◽

2005 ◽

Vol 43 (05) ◽

Author(s):

M Höpfner ◽

A Hüther ◽

V Baradari ◽

D Schuppan ◽

H Scherübl

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Hepatocellular Cancer ◽

Insulin Like Growth Factor ◽

Treatment Approaches ◽

Innovative Treatment ◽

Promising Target

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The behaviour of matrix metalloproteinase-9, hepatocyte growth factor receptor and insulin-like growth factor receptor-I expressions in ulcerative colitis

Zeitschrift für Gastroenterologie ◽

10.1055/s-2006-943409 ◽

2006 ◽

Vol 44 (05) ◽

Author(s):

L Herszényi ◽

F Sipos ◽

O Galamb ◽

I Hritz ◽

B Győrffy ◽

...

Keyword(s):

Ulcerative Colitis ◽

Growth Factor ◽

Matrix Metalloproteinase ◽

Hepatocyte Growth Factor ◽

Growth Factor Receptor ◽

Matrix Metalloproteinase 9 ◽

Insulin Like Growth Factor ◽

Hepatocyte Growth Factor Receptor ◽

Metalloproteinase 9 ◽

Hepatocyte Growth

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Insulin-like growth factor receptor type I as a target for cancer therapy

Frontiers in Bioscience ◽

10.2741/s382 ◽

2013 ◽

Vol S5 (2) ◽

pp. 439-450 ◽

Author(s):

Nathalie Corvaia

Keyword(s):

Growth Factor ◽

Cancer Therapy ◽

Growth Factor Receptor ◽

Receptor Type ◽

Type I ◽

Insulin Like Growth Factor

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Faculty Opinions recommendation of Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021553.244662 ◽

2004 ◽

Author(s):

Rudy Juliano

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Insulin Like Growth Factor ◽

Receptor Signaling ◽

Selective Modulation ◽

Growth Factor Receptor Signaling

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Localization of Type I Insulin-Like Growth Factor Receptor Messenger RNA in the Adult Rat Brain byin SituHybridization

Molecular Endocrinology ◽

10.1210/mend-5-8-1158 ◽

1991 ◽

Vol 5 (8) ◽

pp. 1158-1168 ◽

Author(s):

Jonathan L. Marks ◽

Daniel Porte ◽

Denis G. Baskin

Keyword(s):

Growth Factor ◽

Rat Brain ◽

Messenger Rna ◽

Growth Factor Receptor ◽

Type I ◽

Insulin Like Growth Factor ◽

Adult Rat ◽

Adult Rat Brain

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The type II insulin-like growth factor receptor does not mediate increased DNA synthesis in H-35 hepatoma cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)90803-3 ◽

1984 ◽

Vol 259 (20) ◽

pp. 12705-12713 ◽

Author(s):

C Mottola ◽

M P Czech

Keyword(s):

Growth Factor ◽

Dna Synthesis ◽

Growth Factor Receptor ◽

Hepatoma Cells ◽

Insulin Like Growth Factor ◽

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