Intracellular fluorescence competition assay for inhibitor engagement of histone deacetylase

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2021.128207 ◽

2021 ◽

pp. 128207

Author(s):

Sasha Padilla-Coley ◽

Elley E. Rudebeck ◽

Bradley D. Smith ◽

Frederick M. Pfeffer

Keyword(s):

Histone Deacetylase ◽

Competition Assay ◽

Intracellular Fluorescence

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147: Low Concentration of a Histone Deacetylase Inhibitor, Depsipeptide (FK228), Enhances the Effect of Gemcitabine and Docetaxel in Hormone Refractory Prostate Cancer Cells

The Journal of Urology ◽

10.1016/s0022-5347(18)30412-9 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 50-51

Author(s):

Masatoshi Kanzaki ◽

Hideaki Kakinuma ◽

Teruaki Kumazawa ◽

Takamitsu Inoue ◽

Mitsuru Saito ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hormone Refractory Prostate Cancer ◽

Prostate Cancer Cells ◽

Low Concentration ◽

Deacetylase Inhibitor ◽

Hormone Refractory

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271: The Potential Clinical Application of Histone Deacetylase Inhibitors on Androgen Independent Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)32538-2 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 90-90

Author(s):

Zhengwang Zhang ◽

Jennifer Stanfield ◽

Jer-Tsong Hsieh

Keyword(s):

Prostate Cancer ◽

Histone Deacetylase ◽

Clinical Application ◽

Histone Deacetylase Inhibitors ◽

Potential Clinical Application ◽

Androgen Independent

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Histone deacetylase 6– HDAC6– a new regulator of glucocorticoid receptor-mediated metabolic processes

Diabetologie und Stoffwechsel ◽

10.1055/s-0030-1254011 ◽

2010 ◽

Vol 5 (S 01) ◽

Author(s):

R Winkler ◽

M Clemenz ◽

M Bloch ◽

A Foryst-Ludwig ◽

C Böhm ◽

...

Keyword(s):

Glucocorticoid Receptor ◽

Histone Deacetylase ◽

Histone Deacetylase 6 ◽

Metabolic Processes

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Structure-activity investigations of Santacruzamate A, a potent histone deacetylase inhibitor isolated from a Panamanian cyanobacterium

Planta Medica ◽

10.1055/s-0032-1320383 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

CM Pavlik ◽

MJ Balunas

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Structure Activity ◽

Deacetylase Inhibitor

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Expression of different histone deacetylases and functional effects of histone deacetylase inhibitors in hepatocellular carcinoma

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612774 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

P Dietrich ◽

K Freese ◽

W Thasler ◽

C Hellerbrand

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylases ◽

Histone Deacetylase Inhibitors

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Induction of apoptosis in hepatocellular carcinoma by a novel combination of histone deacetylase inhibitor LBH589

10.1055/s-0039-3402242 ◽

2020 ◽

Author(s):

P Mester ◽

E Aschenbrenner ◽

C Kunst ◽

K Gülow ◽

M Müller-Schilling

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Deacetylase Inhibitor ◽

Induction Of Apoptosis

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Activity of the histone acetyl transferase, histone deacetylase, ROS content and antioxidant activity in the cells of callus culture of Arabidopsis thaliana at the initial stages of acute osmotic stress

Fiziologia rastenij i genetika ◽

10.15407/frg2016.01.043 ◽

2016 ◽

Vol 48 (1) ◽

pp. 43-49

Author(s):

S.I. Jadko ◽

Keyword(s):

Antioxidant Activity ◽

Arabidopsis Thaliana ◽

Osmotic Stress ◽

Histone Deacetylase ◽

Callus Culture ◽

Histone Acetyl Transferase

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Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels

Forum on Immunopathological Diseases and Therapeutics ◽

10.1615/forumimmundisther.v2.i2.40 ◽

2011 ◽

Vol 2 (2) ◽

pp. 127-135 ◽

Author(s):

Luigi Inguglia ◽

Monica Notarbartolo ◽

Paola Poma ◽

Manuela Labbozzetta ◽

Natale D'Alessandro

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Molecular Analysis ◽

Histone Deacetylase Inhibitor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Induction Of Apoptosis

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2074-P: Histone Deacetylase Inhibitors Improve Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells

Diabetes ◽

10.2337/db20-2074-p ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 2074-P

Author(s):

CHIH-CHUN LEE ◽

TATSUYOSHI KONO ◽

STACI A. WEAVER ◽

PAUL SOHN ◽

CARMELLA EVANS-MOLINA

Keyword(s):

Insulin Secretion ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Calcium Entry ◽

Store Operated Calcium Entry ◽

Glucose Stimulated Insulin Secretion

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Central endothelial-1 produces analgesic function by triggering spinal neuronal histone deacetylase 5 (HDAC5) nucleocytoplasmic shuttling under neuropathic pain

10.26226/morressier.5ab3c87fa874c6002655949c ◽

2018 ◽

Author(s):

Pan Gu

Keyword(s):

Neuropathic Pain ◽

Histone Deacetylase ◽

Nucleocytoplasmic Shuttling

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