Sex hormone-binding globulin, estradiol, and bone turnover markers in male osteoporosis

Bone ◽  
2004 ◽  
Vol 34 (6) ◽  
pp. 933-939 ◽  
Author(s):  
C Lormeau ◽  
B Soudan ◽  
M d'Herbomez ◽  
P Pigny ◽  
B Duquesnoy ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Sex Hormone ◽  
Male Osteoporosis ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Turnover Markers

Effect of postponing puberty and cross-sex hormone therapy on bone turnover markers and BMAD in transgender adolescents

2016 ◽  
Author(s):  
Mariska Vlot ◽  
Daniel Klink ◽  
Heijer Martin den ◽  
Marinus Blankenstein ◽  
Joost Rotteveel ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Hormone Therapy ◽  
Bone Turnover Markers ◽  
Sex Hormone ◽  
Turnover Markers

scholarly journals Serum Estradiol, Testosterone, and Sex Hormone-Binding Globulin as Regulators of Peak Bone Mass and Bone Turnover Rate in Young Finnish Men

2004 ◽  
Vol 89 (8) ◽  
pp. 3785-3789 ◽  
Author(s):  
Ville-Valtteri Välimäki ◽  
Henrik Alfthan ◽  
Kaisa K. Ivaska ◽  
Eliisa Löyttyniemi ◽  
Kim Pettersson ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Turnover Rate ◽  
Peak Bone Mass ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Serum Estradiol ◽  
Hormone Binding

Effect of suppression of puberty and cross-sex hormone therapy on bone turnover markers and BMAD in transgender adolescents

2016 ◽  
Vol 62 (5) ◽  
pp. 22-23
Author(s):  
Mariska Caroline Vlot ◽  
Daniel T. Klink ◽  
Martin Den Heijer ◽  
Marinus A. Blankenstein ◽  
Joost Rotteveel ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Hormone Therapy ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Sex Hormone ◽  
Added Value ◽  
Mineral Density ◽  
Bone Mineral Apparent Density ◽  
Z Scores ◽  
Turnover Markers

Background: Puberty is highly important for the accumulation of bone mass. Bone turnover and bone mineral density can be affected in transgender adolescents when puberty is suppressed by gonadotropin-releasing hormone analogues (GnRHa), followed by treatment with cross-sex hormone therapy (CSHT).Objective: To investigate the effect of GnRHa and CSHT on bone turnover markers (BTMs) and bone mineral apparent density (BMAD) in transgender adolescents.Methods: Thirty four female-to-males (FtMs) and 22 male-to-females (MtFs) were divided into a young and old pubertal group, based on the bone age of 14 years in the FtMs and 15 years in the MtFs. All patients received GnRHa triptorelin. CSHT was prescribed in incremental doses from the age of 16 years. FtMs received testosterone ester mixture and MtFs were treated with 17-β estradiol. BTMs P1NP, osteocalcin and ICTP and the BMD of lumbar spine (LS) and femoral neck (FN) were measured at three time points. Furthermore, BMAD and Z-scores were calculated.Results: P1NP and 1CTP decreased during GnRHa treatment, indicating decreased bone turnover. Osteocalcin showed an aberrant pattern. A low BMAD Z-score of both FN and LS was observed in the MtFs at start of GnRHa treatment. The decrease in bone turnover upon GnRHa treatment was accompanied by an unchanged BMAD of both FN and LS, however BMAD Z-scores of predominantly the LS decreased. Twenty-four months after CSHT the BTMs P1NP and ICTP were even more decreased. During CSHT BMAD Z-scores increased and returned towards normal, especially of the LS.Conclusion: Suppressing puberty by GnRHa leads to a decrease of BTMs in transgender adolescents. The increase of BMAD and BMAD Z-scores predominantly in the LS as a result of treatment with CSHT is accompanied by decreasing BTM concentrations after 24 months of CSHT. Therefore, the added value of evaluating BTMs seems to be limited and DEXA-scans remain important in follow-up of transgender adolescents. 

scholarly journals SAT0157 The sex hormone binding globulin in male osteoporosis

2001 ◽  
Author(s):  
ER Legrand ◽  
C Gibert ◽  
Y Gallois ◽  
E Mathieu ◽  
F Boux de casson ◽  
...  
Keyword(s):  
Sex Hormone ◽  
Male Osteoporosis ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding

scholarly journals Vitamin D status and sex hormone binding globulin: Determinants of bone turnover and bone mineral density in elderly women

2009 ◽  
Vol 10 (8) ◽  
pp. 1177-1184 ◽  
Author(s):  
Marcel E. Ooms ◽  
Paul Lips ◽  
Jan C. Roos ◽  
Wim J. F. van der Vijgh ◽  
Corrie Popp-Snijders ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Elderly Women ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Vitamin D Status ◽  
Hormone Binding ◽  
Mineral Density

Effect of pubertal suppression and cross-sex hormone therapy on bone turnover markers and bone mineral apparent density (BMAD) in transgender adolescents

Bone ◽  
2017 ◽  
Vol 95 ◽  
pp. 11-19 ◽  
Author(s):  
Mariska C. Vlot ◽  
Daniel T. Klink ◽  
Martin den Heijer ◽  
Marinus A. Blankenstein ◽  
Joost Rotteveel ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Hormone Therapy ◽  
Bone Mineral ◽  
Apparent Density ◽  
Bone Turnover Markers ◽  
Sex Hormone ◽  
Bone Mineral Apparent Density ◽  
Turnover Markers

Alendronate daily, weekly in conventional tablets and weekly in enteric tablets: preliminary study on the effects in bone turnover markers and incidence of side effects

2003 ◽  
Vol 23 (3) ◽  
pp. 278-281
Author(s):  
J. E. Blümel ◽  
C. Castelo-Branco ◽  
G. De La Cuadra ◽  
L. Maciver ◽  
M. Moreno ◽  
...  
Keyword(s):  
Side Effects ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Preliminary Study ◽  
Turnover Markers
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