Phalangeal quantitative ultrasound and bone mineral density in evaluating cortical bone loss: A study in postmenopausal women with hyperparathyroidism and subclinical iatrogenic hyperthyroidism

The objective was to study the independent relationships of body mass index and endogenous estradiol to cortical bone mineral density and the rate of cortical bone loss at the radius in healthy early postmenopausal women. Fifty-one healthy early postmenopausal women (aged 58–66 years) participated. The women were a subset of a population participating in a 10-year longitudinal study to elucidate the influence of dietary calcium on the rate of cortical bone loss. Cortical bone mineral density at the radius, body weight and body height were measured annually (1979–89). Concentrations of sex steroids were measured in serum samples collected during the last year of follow-up (1989). Endogenous estradiol levels, although significantly positively correlated with body mass index, were not independently related to bone mass indices of the radius. Body mass index, on the other hand, was found to be positively related to cortical bone mineral density and negatively to the rate of bone loss, even after adjustments had been made for confounding factors. Our results suggest that the level of total estradiol is not an important determinant of cortical bone mass indices in healthy early postmenopausal women. Other factors of overweight such as mechanical loading may be important.

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Postmenopausal Women With Colles' Fracture Have Lower Values of Bone Mineral Density Than Controls as Measured by Quantitative Ultrasound and Densitometry

Journal of Clinical Densitometry ◽

10.1385/jcd:8:4:430 ◽

2005 ◽

Vol 8 (4) ◽

pp. 430-435 ◽

Cited By ~ 5

Author(s):

Manuel Sosa ◽

P. Saavedra ◽

J. del Pino-Montes ◽

J. Alegre ◽

R. Pérez-Cano ◽

...

Keyword(s):

Bone Mineral Density ◽

Postmenopausal Women ◽

Bone Mineral ◽

Quantitative Ultrasound ◽

Mineral Density ◽

Colles Fracture

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Effect of BMI(Body Mass Index) on BMD (Bone Mineral Density) in Postmenopausal Women

Journal of Dhaka Medical College ◽

10.3329/jdmc.v28i1.45758 ◽

2020 ◽

Vol 28 (1) ◽

pp. 60-66

Author(s):

Tabassum Ghani ◽

Subinoy Krishna Paul ◽

Afrina Begum ◽

Noorjahan ◽

Mandira Sarkar ◽

...

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Bone Loss ◽

Postmenopausal Women ◽

Body Mass ◽

Bone Mineral ◽

Significant Positive Correlation ◽

Mineral Density ◽

Positive Correlation ◽

Medical College

Menopause is commonly associated with rapid bone loss and this bone loss manifests as a significant decrease in bone mineral density (BMD). Body weight or body mass index is the most important factor which influences BMD. Aim of this study was to evaluate the association between BMI and BMD in post menopausal women. Also to measure the correlation between age, duration of menopause, weight with BMD. This cross-sectional study was undertaken in the Department of Obstetrics and Gynaecology in Dhaka Medical College Hospital, Dhaka from January, 2012 to December, 2012. The study included women of 50 to 70 years who had menopause with three or more parity. Total 100 women were evaluated by history taking, physical examination and laboratory investigation (BMD).The results showed that there was significant positive correlation between BMI and BMD value of L1-4 and total femur (Pearson‘s coefficient was +0.285, P<0.01 and +.350, P<.001). There was also significant positive correlation between weight and T- score of L1-4 (r =+ .482, P<.01) and Total femur (r = +.513, P< .01). In addition, significant negative correlation was found between BMD with age and duration of menopause. It can be concluded that in postmenopausal women as the BMI decreases bone mineral density also decreases. So, adequate weight and BMI necessary for the prevention of osteoporosis. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 60-66

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