Radiation-induced damage in the upper gastrointestinal tract: clinical presentation, diagnostic tests and treatment options

2020 ◽  
Vol 48-49 ◽  
pp. 101711
Author(s):  
Ahmed N.A.M. Afifi ◽  
Maciej Powerski ◽  
Dörthe Jechorek ◽  
Thomas B. Brunner ◽  
Jochen Weigt ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Diagnostic Tests ◽  
Clinical Presentation ◽  
Treatment Options ◽  
Upper Gastrointestinal Tract ◽  
Radiation Induced ◽  
Upper Gastrointestinal

Cervical Carcinoma: Postoperative Radiotherapy: Fifteen-Year Experience in a Norwegian Health Region

2009 ◽  
Vol 19 (9) ◽  
pp. 1595-1599 ◽  
Author(s):  
Elke Lorenz ◽  
Trond Strickert ◽  
Bjørn Hagen
Keyword(s):  
Gastrointestinal Tract ◽  
Cervical Carcinoma ◽  
Postoperative Radiotherapy ◽  
Treatment Options ◽  
Combined Treatment ◽  
Intensity Modulated Radiation Therapy ◽  
Upper Gastrointestinal Tract ◽  
New Treatment ◽  
Grade 3 ◽  
Upper Gastrointestinal

Introduction:To study the results in cervical carcinoma after a combined treatment with surgery and radiotherapy with regard to survival and side effects.Methods:A retrospective analysis of 71 patients who underwent radical hysterectomy and postoperative radiotherapy between January 1, 1987, and December 31, 2001, was performed.Results:Median follow-up periods were 162 months for surviving patients and 62 months for deceased patients. The 5-year overall survival and disease-specific survival for all stages were 80.3% and 82.7%, respectively. The 5-year actuarial incidence of late reactions for grade 1 + 2 was as follows: for upper gastrointestinal tract, 36%; for rectum, 37%; for urinary tract, 19%; for vagina, 26%; and for lymph edema, 19%. The 5-year actuarial incidence of late reactions for grade 3 + 4 was as follows: for upper gastrointestinal tract, 12%; and for rectum, 3%.Conclusions:Careful pretreatment workup and well-defined criteria for postoperative radiotherapy are essential, and new treatment options such as intensity-modulated radiation therapy should be considered.

scholarly journals Upper Gastrointestinal Tract Crohn's Disease

1990 ◽  
Vol 4 (1) ◽  
pp. 26-32 ◽  
Author(s):  
Hugh J Freeman
Keyword(s):  
Crohn’S Disease ◽  
Gastrointestinal Tract ◽  
Crohn's Disease ◽  
Treatment Options ◽  
Upper Gastrointestinal Tract ◽  
Distal Intestine ◽  
The Subject ◽  
Atypical Presentations ◽  
Upper Gastrointestinal

Crohn's disease may involve any site within the gastrointestinal tract. Usually pathology is present in the ileum and/or colon, but atypical presentations may occur with apparently 'isolated' involvement of the oropharynx, esophagus or gastroduodenum. If changes typical of Crohn's disease are detected in the upper gastrointestinal tract, then a careful assessment is required involving radiographic, endoscopic and histologic studies to determine if pathology is present in more distal intestine. In addition , microbiologic studies may be important to exclude infectious causes, especially of granulomas. If these studies are negative, prolonged follow-up may be required to establish a diagnosis of Crohn's disease. Although upper gastrointestinal involvement is increasingly recognized as a significant cause of morbidity in Crohn's disease, the treatment options are limited , largely anecdotal and need to be the subject of detailed epidemiologic investigation and clinical trials.

Radiological Manifestations of Radiation-Induced Injury to the Normal Upper Gastrointestinal Tract

Radiology ◽  
1975 ◽  
Vol 117 (1) ◽  
pp. 135-140 ◽  
Author(s):  
Harvey M. Goldstein ◽  
Lee F. Rogers ◽  
Gilbert H. Fletcher ◽  
Gerald D. Dodd
Keyword(s):  
Gastrointestinal Tract ◽  
Upper Gastrointestinal Tract ◽  
Radiation Induced ◽  
Upper Gastrointestinal

Intraluminal Pressures from the Upper Gastrointestinal Tract

1957 ◽  
Vol 32 (6) ◽  
pp. 1013-1024 ◽  
Author(s):  
E. Clinton Texter ◽  
Hubbard W. Smith ◽  
Hugo C. Moeller ◽  
Clifford J. Barborka
Keyword(s):  
Gastrointestinal Tract ◽  
Upper Gastrointestinal Tract ◽  
Upper Gastrointestinal
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