scholarly journals Creation of Scaffold-Free Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) Cell Sheets for Drug Screening and Regenerative Medicine

2019 ◽  
Vol 116 (3) ◽  
pp. 273a
Author(s):  
Xie He ◽  
Ana Da ◽  
Silva Costa ◽  
Francis L. Burton ◽  
Godfrey L. Smith
Keyword(s):  
Stem Cell ◽  
Regenerative Medicine ◽  
Drug Screening ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Cell Sheets ◽  
Induced Pluripotent

scholarly journals Young at Heart: Pioneering Approaches to Model Nonischaemic Cardiomyopathy with Induced Pluripotent Stem Cells

2016 ◽  
Vol 2016 ◽  
pp. 1-15 ◽  
Author(s):  
Aoife Gowran ◽  
Marco Rasponi ◽  
Roberta Visone ◽  
Patrizia Nigro ◽  
Gianluca L. Perrucci ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Induced Pluripotent Stem Cells ◽  
Drug Screening ◽  
Pluripotent Stem Cells ◽  
Pluripotent Stem Cell ◽  
Human Fibroblasts ◽  
Induced Pluripotent Stem Cell ◽  
Induced Pluripotent

A mere 9 years have passed since the revolutionary report describing the derivation of induced pluripotent stem cells from human fibroblasts and the first in-patient translational use of cells obtained from these stem cells has already been achieved. From the perspectives of clinicians and researchers alike, the promise of induced pluripotent stem cells is alluring if somewhat beguiling. It is now evident that this technology is nascent and many areas for refinement have been identified and need to be considered before induced pluripotent stem cells can be routinely used to stratify, treat and cure patients, and to faithfully model diseases for drug screening purposes. This review specifically addresses the pioneering approaches to improve induced pluripotent stem cell based models of nonischaemic cardiomyopathy.

Induced pluripotent stem cell‐derived extracellular vesicles: A novel approach for cell‐free regenerative medicine

2018 ◽  
Vol 234 (6) ◽  
pp. 8455-8464 ◽  
Author(s):  
Behnaz Taheri ◽  
Masoud Soleimani ◽  
Sedigheh Fekri Aval ◽  
Elaheh Esmaeili ◽  
Zahra Bazi ◽  
...  
Keyword(s):  
Stem Cell ◽  
Regenerative Medicine ◽  
Extracellular Vesicles ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Novel Approach ◽  
Induced Pluripotent

scholarly journals Drug Screening Using a Library of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity

Circulation ◽  
2013 ◽  
Vol 127 (16) ◽  
pp. 1677-1691 ◽  
Author(s):  
Ping Liang ◽  
Feng Lan ◽  
Andrew S. Lee ◽  
Tingyu Gong ◽  
Veronica Sanchez-Freire ◽  
...  
Keyword(s):  
Stem Cell ◽  
Drug Screening ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Induced Pluripotent ◽  
Disease Specific
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