scholarly journals Direct Detection and Characterization of a Phosphoinositide Dependent Kinase-1 (PDK1) Homodimer on a Target Membrane Surface Via Single Molecule Fluorescence

2020 ◽  
Vol 118 (3) ◽  
pp. 558a
Author(s):  
Moshe T. Gordon ◽  
Joseph J. Falke
Keyword(s):  
Single Molecule ◽  
Direct Detection ◽  
Membrane Surface ◽  
Single Molecule Fluorescence ◽  
Target Membrane ◽  
Phosphoinositide Dependent Kinase

scholarly journals Quantitative characterization of fluorophores in multi-component nanoprobes by single-molecule fluorescence

2011 ◽  
Vol 2 (10) ◽  
pp. 2761 ◽  
Author(s):  
Ambika Bumb ◽  
Susanta K. Sarkar ◽  
Xufeng S. Wu ◽  
Martin W. Brechbiel ◽  
Keir C. Neuman
Keyword(s):  
Single Molecule ◽  
Single Molecule Fluorescence ◽  
Quantitative Characterization

scholarly journals In situ genotyping of a pooled strain library after characterizing complex phenotypes

2017 ◽  
Author(s):  
Michael J. Lawson ◽  
Daniel Camsund ◽  
Jimmy Larsson ◽  
Özden Baltekin ◽  
David Fange ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Single Molecule ◽  
Single Molecule Fluorescence ◽  
Detailed Characterization ◽  
E Coli ◽  
Complex Phenotypes

So far, it has not been possible to perform advanced microscopy on pool generated strain libraries and at the same time know each strain’s genotype. We have overcome this barrier by identifying the genotypes for individual cells in situ after a detailed characterization of the phenotype. The principle is demonstrated by single molecule fluorescence imaging of E. coli strains harboring barcoded plasmids that express a sgRNA which suppress different genes through dCas9.

scholarly journals Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

2008 ◽  
Vol 105 (38) ◽  
pp. 14424-14429 ◽  
Author(s):  
A. Orte ◽  
N. R. Birkett ◽  
R. W. Clarke ◽  
G. L. Devlin ◽  
C. M. Dobson ◽  
...  
Keyword(s):  
Single Molecule ◽  
Single Molecule Fluorescence

scholarly journals Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α-Synuclein Oligomers

2015 ◽  
Vol 87 (17) ◽  
pp. 8818-8826 ◽  
Author(s):  
Mathew H. Horrocks ◽  
Laura Tosatto ◽  
Alexander J. Dear ◽  
Gonzalo A. Garcia ◽  
Marija Iljina ◽  
...  
Keyword(s):  
Single Molecule ◽  
Single Molecule Fluorescence ◽  
Rapid Characterization ◽  
Fast Flow
Sign in / Sign up

Export Citation Format

Share Document