scholarly journals Biophysical Characterization and Structural Studies of Small Multidrug Resistance Family of Transporters

2021 ◽  
Vol 120 (3) ◽  
pp. 70a
Author(s):  
Ali A. Kermani ◽  
Christian B. Macdonald ◽  
Randy Stockbridge
Keyword(s):  
Multidrug Resistance ◽  
Structural Studies ◽  
Biophysical Characterization ◽  
Small Multidrug Resistance

scholarly journals Overlapping Substrate Specificities in the Small Multidrug Resistance (SMR) Family of Transporters

2020 ◽  
Vol 118 (3) ◽  
pp. 130a
Author(s):  
Christian B. Macdonald ◽  
Ali A. Kermani ◽  
Randy B. Stockbridge
Keyword(s):  
Multidrug Resistance ◽  
Substrate Specificities ◽  
Small Multidrug Resistance

scholarly journals Overexpression of the Escherichia coli sugE Gene Confers Resistance to a Narrow Range of Quaternary Ammonium Compounds

2002 ◽  
Vol 184 (9) ◽  
pp. 2543-2545 ◽  
Author(s):  
Yong Joon Chung ◽  
Milton H. Saier
Keyword(s):  
Escherichia Coli ◽  
Drug Resistance ◽  
Multidrug Resistance ◽  
Quaternary Ammonium ◽  
Narrow Range ◽  
Quaternary Ammonium Compounds ◽  
High Level Expression ◽  
Small Multidrug Resistance ◽  
High Level ◽  
Ammonium Compounds

ABSTRACT SugE of Escherichia coli, first identified as a suppressor of groEL mutations but a member of the small multidrug resistance family, has not previously been shown to confer a drug resistance phenotype. We show that high-level expression of sugE leads to resistance to a subset of toxic quaternary ammonium compounds.

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