Diffusion restriction in the corticospinal tracts and the corpus callosum in neonates after cerebral insult

2017 ◽  
Vol 39 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Monika Bekiesinska-Figatowska ◽  
Agnieszka Duczkowska ◽  
Sylwia Szkudlinska-Pawlak ◽  
Marek Duczkowski ◽  
Jaroslaw Madzik ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Diffusion Restriction ◽  
Corticospinal Tracts ◽  
Cerebral Insult

scholarly journals A Pictorial Review on Reversible Splenial Lesions

2021 ◽  
Author(s):  
Arpita Sahu ◽  
Kartik Mittal ◽  
Namita Kamath ◽  
Nandakumar PG ◽  
Amit Sahu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Corpus Callosum ◽  
Definitive Diagnosis ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Irreversible Damage ◽  
Laboratory Findings ◽  
Diffusion Restriction ◽  
Pictorial Review ◽  
Magnetic Resonance Imaging Mri

AbstractSplenium of corpus callosum can be involved in a variety of pathologies causing reversible or irreversible damage. Magnetic resonance imaging (MRI) is a useful investigation to evaluate the same. In spite of the differing etiologies implicated, MRI findings can be quite common. We review the reversible causes of diffusion restriction involving the splenium of corpus callosum and highlight the etiopathologic mechanisms implicated in these pathologies. We further discuss these pathologies in entirety with relevant clinical and laboratory findings helping make definitive diagnosis and guiding appropriate management.

scholarly journals P.172 Diffusion MRI characteristics change in select cerebral white matter tracts after decompressive surgery for degenerative cervical myelopathy

2021 ◽  
Vol 48 (s3) ◽  
pp. S69-S69
Author(s):  
AC Friesen ◽  
SA Detombe ◽  
P Doyle-Pettypiece ◽  
H Haddad ◽  
W Ng ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corpus Callosum ◽  
Cervical Myelopathy ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Recovery Period ◽  
White Matter Tracts ◽  
Corticospinal Tracts ◽  
Degenerative Cervical Myelopathy

Background: Degenerative cervical myelopathy is characterized by progressive compression of the spinal cord resulting in debilitating loss of dexterity, independent ambulation, and sphincter control. Diffusion tensor imaging (DTI) has shown that, compared to healthy controls, myelopathy patients have decreased integrity of the corticospinal tracts and corpus callosum (Bernabeu-Sanz et al, 2020). Methods: Twenty-six myelopathy patients consented to cerebral diffusion tensor imaging (3 Tesla, 32 directions, b=1000) preoperatively, as well as 6-weeks, 12-weeks, and 6-months postoperatively. Average mean diffusivity (MD), fractional anisotropy (FA), radial diffusivity (RD), and axial diffusivity (AD) were measured in the corticospinal tracts, forceps major, and forceps minor. Results: Both MD and RD decreased from 6-12 weeks postoperatively in the right corticospinal tract. The forceps major of the corpus callosum showed an initial postoperative increase in MD followed by a subsequent increase in FA and decrease in RD 3-6 months postoperatively. The AD of the forceps major increased both immediately and 3-6 months postoperatively. Conclusions: Changes in microstructural integrity of the corticospinal tract and forceps major over the postoperative recovery period suggest a pattern of recovery in myelopathy patients. This study is the first to report postoperative DTI changes in myelopathy-relevant white matter tracts in the brain.

scholarly journals Metronidazole-Induced Encephalopathy in a Patient with End-Stage Liver Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
John P. Knorr ◽  
Imran Javed ◽  
Neha Sahni ◽  
Ceylan Z. Cankurtaran ◽  
Jorge A. Ortiz
Keyword(s):  
Liver Disease ◽  
Hepatic Encephalopathy ◽  
Corpus Callosum ◽  
Diffusion Restriction ◽  
End Stage Liver Disease ◽  
Short Course ◽  
Liver Transplant Waiting List ◽  
End Stage ◽  
Inferior Colliculi

Purpose. Metronidazole-induced encephalopathy (MIE) has been rarely reported. We report a case in a patient with end-stage liver disease (ESLD).Summary. A 63-year-old male with ESLD secondary to hepatitis C virus presented with progressively worsening fatigue, slurred speech, aphasia, vomiting, and left-sided facial droop after completing a 2-week course of metronidazole for recurrentClostridium difficile-associated diarrhea. He completed a previous course of metronidazole 3 weeks prior to presentation. He is on the liver transplant waiting list and has known hepatic encephalopathy. MRI revealed hyperintense T2 signals involving the bilateral dentate nuclei, inferior colliculi and splenium of the corpus callosum, and increased diffusion restriction at the splenium of the corpus callosum. His neurological function improved over the next several days. He underwent liver transplantation 6 days after admission. A follow-up MRI 6 weeks after presentation revealed resolution of abnormalities; however, paresthesias persisted 6 months after MIE diagnosis.Conclusion. An ESLD patient with hepatic encephalopathy developed MIE after a relatively short course of metronidazole. Metronidazole has been shown to accumulate in patients with ESLD. Increased awareness for neurotoxicity when using metronidazole in ESLD patients is warranted, especially in those with potentially confounding hepatic encephalopathy.

Corpus callosum may be similar in children with ADHD and siblings of children with ADHD

2000 ◽  
Vol 42 (01) ◽  
pp. 8 ◽  
Author(s):  
S Overmeyer ◽  
A Simmons ◽  
J Santosh ◽  
C Andrew ◽  
S C R Williams ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Children With Adhd
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