Incidence and risk factors of acute encephalopathy with biphasic seizures in febrile status epilepticus

Author(s):  
Fumio Ichinose ◽  
Takuji Nakamura ◽  
Ryutaro Kira ◽  
Kenji Furuno ◽  
Shigeki Ishii ◽  
...  

2020 ◽  
Vol 14 (1) ◽  
pp. 95-102
Author(s):  
Mohammad Vafaee-Shahi ◽  
Elaheh Soltanieh ◽  
Hossein Saidi ◽  
Aina Riahi

Background: Risk factors identification associated with status epilepticus is valuable in order to prevent morbidity and mortality in children. This study aimed to consider the etiology, risk factors, morbidity and mortality in children with status epilepticus. Methods: This retrospective cross-sectional study was performed on 119 patients aged from one month old to 15 years old. Patients’ data were recorded, including basic demographic, etiology and clinical information. The different risk factors correlated to morbidity and mortality were evaluated in this study. Results: The most common etiologies were acute symptomatic and febrile status epilepticus by 32.8% and 22.7%, respectively. Abnormal brain imaging results were reported far more frequently in patients with a history of neurodevelopmental delay and previous status epilepticus (p<0.001). The overall morbidity and mortality rates were 18.9% and 10.9%, respectively; while these rates in patients with delayed development (45.16% and 18.42%, respectively) were significantly higher than patients with normal development (8% and 7.4%, respectively). The morbidity rates in patients with previous seizures and previous status epilepticus were remarkably higher than those without previous history of seizure (26.41% vs 11.32%; p=0.047) and without previous status epilepticus (36.36% versus 14.28%; p=0.018). The length of hospital stay in patients with mortality was considerably longer than patients without mortality (12.30 ± 16.1 days vs 7.29 ± 6.24 days; p=0.033). The mortality rate in patients with normal Lumbar Puncture result was notably lower than those with abnormal LP result (2.9% vs 50%). The morbidity rate in patients with abnormal brain imaging results (p<0.001) was significantly greater than those in patients with normal results. The mortality rate was relatively higher in patients with abnormal imaging results compared to those normal results. Etiology was an important predictor of mortality and morbidity rates; acute symptomatic (32.8%), febrile status epilepticus (22.7%) and remote symptomatic (16.8%) etiologies were the most common underlying causes of S.E. While in children less than 3 years old, the acute symptomatic etiology and febrile status epilepticus etiologies were estimated as the most common, in most patients older than 3 years old the most common etiology of status epilepticus was unknown. Congenital brain defects etiology had the highest mortality (36.36%) and morbidity (42.85%) rate. The lowest morbidity (3.84%) and mortality (0%) rates were for patients with febrile status epilepticus etiology. Conclusion: Age, developmental delay, history of previous status epilepticus, the length of hospital stay, abnormal brain imaging results and the underlying etiology of status epilepticus were associated with increased morbidity and mortality among children with status epilepticus.



2019 ◽  
Vol 08 (03) ◽  
pp. 079-082
Author(s):  
Isaac Molinero ◽  
Shlomo Shinnar

AbstractFebrile status epilepticus (FSE) is defined as a febrile seizure lasting 30 minutes or more and is considered the extreme end of the complex febrile seizure spectrum. It remains unclear why some children are predisposed to the development of FSE compared with others. FSE is considered as medical emergency and as such, early treatment is crucial. The consequences of FSE have been a topic of interest for many years, specially its association with temporal lobe epilepsy and hippocampal sclerosis. In this article, we review the epidemiology, risk factors, pathophysiology, treatment, and prognosis including findings from the “Consequences of Prolonged Febrile Seizures in Childhood” (FEBSTAT) study.



2016 ◽  
Vol 38 (2) ◽  
pp. 217-224 ◽  
Author(s):  
Takaoki Yokochi ◽  
Takahito Takeuchi ◽  
Jumpei Mukai ◽  
Yukihiro Akita ◽  
Kojiro Nagai ◽  
...  


2008 ◽  
Vol 29 (4) ◽  
pp. 495-501 ◽  
Author(s):  
F. Viani ◽  
E. Beghi ◽  
A. Romeo ◽  
A. Lierde


2013 ◽  
Vol 163 (4) ◽  
pp. 1147-1151.e1 ◽  
Author(s):  
Dale C. Hesdorffer ◽  
Shlomo Shinnar ◽  
Darrell V. Lewis ◽  
Douglas R. Nordli ◽  
John M. Pellock ◽  
...  


2021 ◽  
Vol 11 (6) ◽  
pp. 811
Author(s):  
Paola De Liso ◽  
Virginia Pironi ◽  
Massimo Mastrangelo ◽  
Domenica Battaglia ◽  
Dana Craiu ◽  
...  

It has been an honor for us to receive a comment on our article “Fatal Status Epilepticus in Dravet Syndrome” [...]



Author(s):  
M. Hidalgo de la Cruz ◽  
J.A. Miranda Acuña ◽  
E. Luque Buzo ◽  
B. Chavarria Cano ◽  
E. Esteban de Antonio ◽  
...  


2017 ◽  
Vol 9 (1) ◽  
pp. 32-39 ◽  
Author(s):  
Kenta Takahara ◽  
Takato Morioka ◽  
Takafumi Shimogawa ◽  
Toshiyuki Amano ◽  
Aoi Kawakita ◽  
...  


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