Etiology, Risk Factors, Mortality and Morbidity of Status Epilepticus in Children: A Retrospective Cross-Sectional Study in Tehran, Iran

Background: Risk factors identification associated with status epilepticus is valuable in order to prevent morbidity and mortality in children. This study aimed to consider the etiology, risk factors, morbidity and mortality in children with status epilepticus. Methods: This retrospective cross-sectional study was performed on 119 patients aged from one month old to 15 years old. Patients’ data were recorded, including basic demographic, etiology and clinical information. The different risk factors correlated to morbidity and mortality were evaluated in this study. Results: The most common etiologies were acute symptomatic and febrile status epilepticus by 32.8% and 22.7%, respectively. Abnormal brain imaging results were reported far more frequently in patients with a history of neurodevelopmental delay and previous status epilepticus (p<0.001). The overall morbidity and mortality rates were 18.9% and 10.9%, respectively; while these rates in patients with delayed development (45.16% and 18.42%, respectively) were significantly higher than patients with normal development (8% and 7.4%, respectively). The morbidity rates in patients with previous seizures and previous status epilepticus were remarkably higher than those without previous history of seizure (26.41% vs 11.32%; p=0.047) and without previous status epilepticus (36.36% versus 14.28%; p=0.018). The length of hospital stay in patients with mortality was considerably longer than patients without mortality (12.30 ± 16.1 days vs 7.29 ± 6.24 days; p=0.033). The mortality rate in patients with normal Lumbar Puncture result was notably lower than those with abnormal LP result (2.9% vs 50%). The morbidity rate in patients with abnormal brain imaging results (p<0.001) was significantly greater than those in patients with normal results. The mortality rate was relatively higher in patients with abnormal imaging results compared to those normal results. Etiology was an important predictor of mortality and morbidity rates; acute symptomatic (32.8%), febrile status epilepticus (22.7%) and remote symptomatic (16.8%) etiologies were the most common underlying causes of S.E. While in children less than 3 years old, the acute symptomatic etiology and febrile status epilepticus etiologies were estimated as the most common, in most patients older than 3 years old the most common etiology of status epilepticus was unknown. Congenital brain defects etiology had the highest mortality (36.36%) and morbidity (42.85%) rate. The lowest morbidity (3.84%) and mortality (0%) rates were for patients with febrile status epilepticus etiology. Conclusion: Age, developmental delay, history of previous status epilepticus, the length of hospital stay, abnormal brain imaging results and the underlying etiology of status epilepticus were associated with increased morbidity and mortality among children with status epilepticus.

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Prevalence of cardiovascular risk factors among municipality workers in Chitradurga, South India

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20194225 ◽

2019 ◽

Vol 6 (5) ◽

pp. 1594

Author(s):

Nalina T. ◽

Ghouse Phasha ◽

Prashanth G. ◽

Sree Devi B. K.

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Alcohol Intake ◽

South India ◽

Smoking History ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Life Years ◽

History Of

Background: Cardiovascular disease (CVD) is the single largest cause for mortality and morbidity in the world. In India, non-communicable diseases (NCDs) were responsible for 53% of deaths and 44% of disability adjusted life years lost. Appropriate assessment and management of cardiovascular risk is vital to prevent fatal and non-fatal heart attacks and strokes and to improve health outcomes in individuals at high risk of cardiovascular events. Diabetes mellitus (DM) and HT are common diseases in adulthood, pre-disposing to many cardiovascular complications, posing a major public health challenge.This study aims to assess the prevalence of cardiovascular risk factors such as diabetes, HT, smoking, alcohol intake, dyslipidaemia and obesity among Municipality workers.Methods: A cross-sectional study was carried out between Jan 2019-June 2019 among 100 Municipality workers in Chitradurga, South India. Socio-demographic details and some of the risk factors such as alcohol intake and smoking history were obtained using a pre-tested, structured questionnaire. Blood pressure & waist circumference were measured by standard methods. Fasting blood sugar & lipid profile were measured.Results: Mean age of study participants was 38.03 years (SD ± 10.9). Out of the study subjects, 21% were known diabetic and 22% were known hypertensive. 34% of the participants had cholesterol level higher than the desirable level of 200 mg/dL. Around 72% had a history of alcohol consumption and 13% had a history of tobacco smoking during the last 1 month. The prevalence of overweight based on BMI (BMI >23) is higher among Municipality workers (56%) compared to the general population (35.4%).Conclusions: Burden of cardiovascular risk factors such as diabetes and HT were high among Municipality Workers of Chitradurga.

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Longitudinal study of calf morbidity and mortality on smallholder farms in southern Ethiopia

PLoS ONE ◽

10.1371/journal.pone.0257139 ◽

2021 ◽

Vol 16 (9) ◽

pp. e0257139

Author(s):

Ephrem Tora ◽

Edget Abayneh ◽

Wasihun Seyoum ◽

Mesfin Shurbe

Keyword(s):

Risk Factors ◽

Cox Regression ◽

Morbidity And Mortality ◽

Southern Ethiopia ◽

Dairy Calf ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Ingestion Time ◽

Calf Mortality

Calf morbidity and mortality are serious constraints in the success of dairy calf production. Thus, the current study was carried out with the objective to estimate the incidence of calf morbidity and mortality and associated risk factors in milk-shed districts of Gamo Zone, Southern Ethiopia. A prospective cohort and cross-sectional survey were employed from November 2019 to April 2020. A total of 196 calves were recruited by simple random sampling. Recruitment of calves was deployed by both the concurrent and prospective cohorts in calves aged below three months in study herds. The crude incidence of calf morbidity and mortality was 30.9% and 8.64%, respectively. The most frequently encountered disorder was calf diarrhea (10.17%), followed by pneumonia (6.5%). The other disorders were septicemia, omphalitis, arthritis, eye problem and miscellaneous cases. Multivariable Cox regression was revealed significant association for the calf vigor status, colostrum ingestion time, colostrum feeding status, dam parity, age at first calving, and related disorders were found risk factors of calf morbidity; likewise, calf vigor status at birth, time of colostrum ingestion and weaning were risk factors determining calf mortality. Calf morbidity and mortality rates recorded in this study were marginally higher than economically tolerable level, therefore, could affect the productivity of smallholder dairying by decreasing the obtainability of replacement heifers. Among significant explanatory factors investigated, colostrum ingestion time, method and amount were found important determinant factors of calf mortality and morbidity under the small-holder farming in the milk-shed districts of the Gamo zone. Therefore, rigorous calf husbandry practice is a need to manipulate the aforementioned calf determinants with subsequent application of tailor-made interventions.

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Prevalence of bone fracture and its association with severe hypoglycemia in Japanese patients with type 1 diabetes

BMJ Open Diabetes Research & Care ◽

10.1136/bmjdrc-2020-002099 ◽

2021 ◽

Vol 9 (1) ◽

pp. e002099

Author(s):

Yuji Komorita ◽

Masae Minami ◽

Yasutaka Maeda ◽

Rie Yoshioka ◽

Toshiaki Ohkuma ◽

...

Keyword(s):

Risk Factors ◽

Type 1 Diabetes ◽

Fracture Risk ◽

Bone Fracture ◽

Severe Hypoglycemia ◽

Japanese Patients ◽

Anatomic Site ◽

Cross Sectional ◽

History Of

IntroductionType 1 diabetes (T1D) is associated with higher fracture risk. However, few studies have investigated the relationship between severe hypoglycemia and fracture risk in patients with T1D, and the results are controversial. Besides, none has investigated the risk factors for fracture in Asian patients with T1D. The aim of the present study was to investigate the prevalence of bone fracture and its relationship between severe hypoglycemia and other risk factors in Japanese patients with T1D.Research design and methodsThe single-center cross-sectional study enrolled 388 Japanese patients with T1D (mean age, 45.2 years; women, 60.4%; mean duration of diabetes, 16.6 years) between October 2019 and April 2020. The occurrence and circumstances of any fracture after the diagnosis of T1D were identified using a self-administered questionnaire. The main outcomes were any anatomic site of fracture and fall-related fracture. Severe hypoglycemia was defined as an episode of hypoglycemia that required the assistance of others to achieve recovery.ResultsA total of 92 fractures occurred in 64 patients, and 59 fractures (64%) were fall-related. Only one participant experienced fracture within the 10 years following their diagnosis of diabetes. In logistic regression analysis, the multivariate-adjusted ORs (95% CIs) of a history of severe hypoglycemia were 2.11 (1.11 to 4.09) for any fracture and 1.91 (0.93 to 4.02) for fall-related fracture. Fourteen of 18 participants with multiple episodes of any type of fracture had a history of severe hypoglycemia (p<0.001 vs no fracture).ConclusionsWe have shown that a history of severe hypoglycemia is significantly associated with a higher risk of bone fracture in Japanese patients with T1D.

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Occurrence, associated risk factors, and treatment of surgical site infections in Pakistan

European Journal of Inflammation ◽

10.1177/2058739220960547 ◽

2020 ◽

Vol 18 ◽

pp. 205873922096054

Author(s):

Faiz Ullah Khan ◽

Yu Fang ◽

Zakir Khan ◽

Farman Ullah Khan ◽

Zafar Iqbal Malik ◽

...

Keyword(s):

Risk Factors ◽

Transurethral Resection ◽

Surgical Site Infections ◽

Exploratory Laparotomy ◽

Cross Sectional Study ◽

Surgical Patients ◽

Related Factors ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Associated Risk Factors

Globally, surgical site infections are one of the common infections which lead to a large amount of mortality and morbidity in postsurgical care. The risk for surgical site infection is multidimensional which includes mainly; patient, surgery, and hospital-related factors. This study is aimed to determine the burden of SSIs along with contributed risk factors. A prospective observational cross-sectional study was conducted in one of the largest public-sector hospitals in Pakistan. A total of 412 patients were recruited in the study with full consent and monitored for 30 days after surgery with direct and indirect surveillance. Overall, in seven different surgical procedures the incidence (29.8%) rate of SSI was observed; in appendectomy ( n = 17, 4.1%), exploratory laparotomy ( n = 51, 12.6%), laparoscopic cholecystectomy ( n = 12, 2.90%), mesh repair ( n = 17, 4.01%), thyroidectomy (5, 1.2%), transurethral resection of the prostate ( n = 11, 2.6%), and transurethral resection of the bladder (10, 2.4%). The average SSI rate in every single procedure was about 18 (4.27%) per surgical procedure out of 123 (29.85%) SSI cases. Types of SSI identified were superficial, deep incisional and organ/space ( n = 76, 18.4%, n = 23, 5.5%, and n = 24, 5.7%). Incidence of SSIs during admission, at readmission, and post-surveillance cases were ( n = 50, 12.1%, n = 25, 6.0% and n = 48, 11.6%). Associated risk factors found contributed to the incidence of SSI ( p < 0.05). Pre-operative ( n = 348, 84.5%) and 6 (1.5%) surgical patients did not received the post-operative antibiotics. The P. aeruginosa ( n = 15, 12.1%) and S. aureus (13, 10.5%). Cefoperazone and sulbactam were the most prescribed antibiotics. Associated risk factors and treatment outcomes of surgical patients have a direct association with the incidence of SSI. Hospital-based antimicrobial stewardship, implementation of surgical guidelines, patient care, and education are needed to develop at wards level in hospitals.

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Analysis of Sociodemographic and Clinical Factors Associated with Hospitalized Stroke Patients of Bangladesh

Faridpur Medical College Journal ◽

10.3329/fmcj.v6i1.7405 ◽

1970 ◽

Vol 6 (1) ◽

pp. 19-23 ◽

Cited By ~ 6

Author(s):

AM Hossain ◽

NU Ahmed ◽

M Rahman ◽

MR Islam ◽

G Sadhya ◽

...

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Ischaemic Heart Disease ◽

Low Income ◽

Heart Diseases ◽

Previous History ◽

Stroke Patients ◽

College Hospital ◽

Cross Sectional ◽

History Of

A hospital based cross sectional study was carried out to analyze prevalence of risk factors for stroke in hospitalized patient in a medical college hospital. 100 patients were chosen using purposive sampling technique. Highest incidence of stroke was between the 6th and 7th decade. Patients came from both urban (54%) and rural (46%) areas and most of them belong to the low-income group (47%). In occupational category; service holder (28%) and retired person (21%) were the highest groups. Most of the study subjects were literate (63%). CT scan study revealed that the incidence of ischaemic stroke was 61% and haemorrhagic stroke 39%. Analysis indicated hypertension as major risk factor for stroke (63%) and major portion of the patients (42.85%) were on irregular or no treatment. Twenty four percent of the patients had heart diseases and out of 24 patients 45.83% were suffering from ischaemic heart disease. The present study detected diabetes in 21% patients. Fifty three percent of the study subjects were smoker, 39% patients had habit of betelnut chewing. Out of 26 female patients, only 23% had history of using oral contraceptives. Majority of the patients were sedentary workers (46%). Thirty seven percent of the stroke patients were obese. Among the stroke patients 9% had previous history of stroke and 3% had TIA respectively. Most of the patients (21%) were awake while they suffered from stroke and the time of occurrence was mostly in the afternoon (46%). This study found that hypertension, cigarette smoking, ischaemic heart disease and diabetes mellitus are the major risk factors prevalent in our community while other risk factors demand further study. Key words: stroke; risk factors; hospitalized patients; Bangladesh. DOI: 10.3329/fmcj.v6i1.7405 Faridpur Med. Coll. J. 2011;6(1): 19-23

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The Cross-Sectional Determinants of Secessionism in Advanced Democracies

Comparative Political Studies ◽

10.1177/0010414004272538 ◽

2005 ◽

Vol 38 (3) ◽

pp. 304-326 ◽

Cited By ~ 72

Author(s):

Jason Sorens

Keyword(s):

Risk Factors ◽

Regression Analysis ◽

Ethnic Identity ◽

Ethnic Conflict ◽

Political System ◽

Regional Level ◽

Cross Sectional ◽

Regional Language ◽

History Of ◽

Advanced Democracies

This article analyzes the “risk factors” of secessionism at the substate, regional level. It seeks to answer the question, What regions are more likely to support more successful secessionist parties? Using new data in cross-sectional regression analysis, the author finds that secessionism involves unique factors not common to other kinds of ethnic conflict. Specifically, in addition to “identity” variables such as regional language and history of independence, the following variables explain secessionist strength: lack of irredentist potential, relative affluence, geographical noncontiguity, population, and multiparty political system. These factors generally serve as activators of ethnic identity rather than a substitute for the same, although there are important cases of nonethnic secessionism.

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Multiple Risk Factors of Alcoholic and Non-Alcoholic Myocardial Infarction Patients

Global Journal of Health Science ◽

10.5539/gjhs.v8n1p62 ◽

2015 ◽

Vol 8 (1) ◽

pp. 62 ◽

Cited By ~ 1

Author(s):

N. Harisharan ◽

Awnish Kumar Singh ◽

Nidhu Ram Dangal ◽

Krishna Mohan Surapaneni ◽

Ashish Joshi

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Premature Death ◽

Current Smoker ◽

Medical Emergency ◽

Past Century ◽

Sociodemographic Characteristics ◽

Mortality Trends ◽

Cross Sectional ◽

Mortality And Morbidity

BACKGROUND: Myocardial infarction (MI) is one of the most critical medical emergency and contributor to morbidity and mortality worldwide. Myocardial infarction is the most common form of coronary heart disease and leading cause of premature death. Past century has seen substantial advancement in the field of medical sciences but still mortality trends due to myocardial infarction is increasing in developing countries including India. We have conducted this study to compare the Sociodemographic characteristics of alcoholic and non alcoholic MI patients admitted in coronary care unit of Saveetha Medical College, Chennai, India. METHODS: An exploratory cross sectional study was performed by enrolling a convenient sample of 100 Myocardial Infarction patients. Information about Sociodemographic characteristics, past medical history, alcohol and tobacco intake, physical activity, psychological stress and biochemical measurements was gathered. RESULTS: The mean age of the respondents was 46 (SD=6) years and majority of them were male i.e. 82%. 100% married and 89% literate, there were 24% past and 22% present alcoholics. Consumption of alcohol on a monthly, weekly and daily basis was 8%, 11% and 5% respectively. Preference to brandy was 67%, rum was 21% and that the beer was 12%. Current smoker were 20% and former were 11%. 93% and 52% respondents were under medication of beta blocker and angiotensin-converting-enzyme (ACE) inhibitors respectively. CONCLUSION: Worldwide, MI is the most common cause of mortality and morbidity and hence early diagnosis and management is most essential. Results from our study revealed that, participants had sedentary lifestyles where risk factors of MI such as alcohol consumption, and smoking does existed.

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Risk Factors that Affect Morbidity and Mortality in Patients with Perforated Peptic Ulcer Diseases in a Teaching Hospital

Ethiopian Journal of Health Sciences ◽

10.4314/ejhs.v30i4.10 ◽

2020 ◽

Vol 30 (4) ◽

Author(s):

Nebyou Seyoum ◽

Daba Ethicha ◽

Zelalem Assefa ◽

Berhanu Nega

Keyword(s):

Risk Factors ◽

Peptic Ulcer ◽

Addis Ababa ◽

Previous History ◽

Perforated Peptic Ulcer ◽

Cross Sectional Study ◽

Morbidity And Mortality ◽

Delayed Presentation ◽

Cross Sectional ◽

Female Ratio

Background: This study was done to identify risk factors that affect the morbidity and mortality of patients operated for a perforated peptic ulcer in a resource-limited setting.Methods: A two years (January 1, 2016 - December 30, 2018) retrospective cross- sectional study was done on patients admitted and operated for PPU at Yekatit 12 Hospital, Addis Ababa,Ethiopia.Results: A total of 93 patients were operated. The median age affected was 29 years (Range 15-75 years). Male to female ratio was 7.5:1. Chewing chat, smoking and alcohol use were seen in 22 (23.6%), 35(37.6%), and 34(36.5%), cases respectively. Only 23.6% gave previous history of dyspepsia. The median duration of illness was 48hours and the duodenal to gastric ulcer perforation ratio was 6.5:1. In majority of the cases (63.3%) the perforation diameter was <10mm (63.3%). Cellan-Jones repair of the perforations was done in 92.5% of cases. A total of 47 complications were seen in 25 cases. The total complications and mortality rates were 25(26.8%) and 6(6.5%) respectively. The most common postoperative complication was pneumonia (13.97%) followed by superficial surgical site infection (10.8%). Mortality rate was highest among patients >50yrs [AOR (95%CI) =2.4(2-30)]. Delayed presentation of >24 hours [AOR (95%CI) =4.3(1.4-13.5)] and a SBP <90mmhg [AOR (95%CI) =4.8(1-24)] were found to be significantly related with higher complication rate.Conclusions: Patients who presented early and immediate corrective measures were instituted had better outcomes while those seen late developed unfavorable out-come with significantly higher complications. Therefore, early detection and treatment of PPU is essential.

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The prevalence and risk factors of musculoskeletal disorders among subcontracted hospital cleaners in Thailand

Journal of Health Research ◽

10.1108/jhr-01-2021-0040 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Thanaphum Laithaisong ◽

Wichai Aekplakorn ◽

Paibul Suriyawongpaisal ◽

Chanunporn Tupthai ◽

Chathaya Wongrathanandha

Keyword(s):

Risk Factors ◽

Musculoskeletal Disorders ◽

Teaching Hospital ◽

Stress Test ◽

Cross Sectional Study ◽

Related Factors ◽

Cross Sectional ◽

Middle Income ◽

Content Type ◽

History Of

PurposeThis research aimed to explore the prevalence of musculoskeletal disorders (MSDs) and related factors among subcontracted cleaners in a teaching hospital in Thailand.Design/methodology/approachA cross-sectional study was conducted of 393 subcontracted cleaners in a teaching hospital, from May to June 2020. Face-to-face interviews were carried out using a standard questionnaire, consisting of four parts: (1) participant characteristics, (2) stress test, (3) work characteristics and (4) standardized Nordic questionnaire, Thai version, for MSDs outcome. Multiple logistic regression analyses were performed to determine the association between MSDs and related factors.FindingsThe prevalence of MSDs was 81.9%, involving mostly the lower back (57.7%), followed by the shoulder (52.6%). Factors significantly associated with MSDs were as follows: male gender (OR = 3.06, 95% CI [1.19, 7.87]), severe stress (OR = 2.72, 95% CI [1.13, 6.54]), history of injuries (OR = 4.37, 95% CI [1.27, 15.11]), mopping posture (OR = 2.81, 95% CI [1.43, 5.50]) and task duration (OR = 1.90, 95% CI [1.01, 3.57] for 2–4 h and OR = 3.39, 95% CI [1.17, 9.86] for more than 4 h). Sick leave due to MSDs was associated with history of injuries, Thai nationality and having another part-time job.Originality/valueThe study findings about MSDs in terms of prevalence and related factors contributed to limited pool of the knowledge among subcontracted hospital cleaners in Thailand and middle-income country settings. With growing popularity in outsourcing cleaning services among hospitals in these countries, the study findings could raise a concern and inform policymakers and hospital administrators the importance of the magnitude and risk factors for MSDs necessitating design of preventive strategies.

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Analysis Factors That Affecting the Incidence of Hypertension in Menopausal Woman

Jurnal Kebidanan Midwiferia ◽

10.21070/midwiferia.v6i1.449 ◽

2020 ◽

Vol 6 (1) ◽

pp. 21-25

Author(s):

Estin Gita Maringga ◽

Nunik Ike Yunia Sari

Keyword(s):

Risk Factors ◽

Statistical Data ◽

Free Variable ◽

Hormonal Contraceptives ◽

Menopausal Woman ◽

Cross Sectional ◽

Menopausal Women ◽

History Of ◽

Using Data ◽

The Village

Hypertension is an increased incidence of blood pressure characterized by the increase of sistole and diastole. Hypertension if not properly administered, can cause a variety of complications such as stroke, heart failure, renal failure, encephalopathy, and others. Based on the statistical data of menopause women risk to experience hypertension of 41% compared with males. This research aims to analyze the risk factors that affect the incidence of hypertension in menopausal women in the village Kayen Kidul. The design of research in this study uses cross sectional, with the population is all menopause women who have hypertension in the village of South Kayen, using simple random samplling technique, obtained as many as 71 respondents . The variables in this study consist of a free variable that is age and a history of the use of KB and variables bound in the form of hypertension in menopausal women. The study was conducted on 16-21 September 2019, collecting data using interview and observation techniques using data collection sheets. Data analysts use linear regression, with calculations using SPSS. The results in this study were obtained from 71 respondents, 59.2% of the mother aged < 60 years, 69% had a history of hormonal contraceptives, 57.6% menopause had hypertension. The aged menopause ≥ 60 years and has a history of hormonal contraceptives have a greater risk of hypertensive incidence in menopause.

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