scholarly journals Configuring intracortical microelectrode arrays and stimulus parameters to minimize neuron loss during prolonged intracortical electrical stimulation

2021 ◽  
Author(s):  
Douglas McCreery ◽  
Martin Han ◽  
Victor Pikov ◽  
Carol Miller
Keyword(s):  
Electrical Stimulation ◽  
Microelectrode Arrays ◽  
Neuron Loss ◽  
Stimulus Parameters

scholarly journals Single-Cell Electrical Stimulation Using CMOS-Based High-Density Microelectrode Arrays

2019 ◽  
Vol 13 ◽  
Author(s):  
Silvia Ronchi ◽  
Michele Fiscella ◽  
Camilla Marchetti ◽  
Vijay Viswam ◽  
Jan Müller ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Single Cell ◽  
Microelectrode Arrays ◽  
High Density

Electrical Stimulation Using Kilohertz-Frequency Alternating Current

2009 ◽  
Vol 89 (2) ◽  
pp. 181-190 ◽  
Author(s):  
Alex R Ward
Keyword(s):  
Electrical Stimulation ◽  
Mechanism Of Action ◽  
Alternating Current ◽  
Transcutaneous Electrical Stimulation ◽  
Muscle Strengthening ◽  
Stimulation Parameters ◽  
Stimulus Parameters ◽  
Stimulation Of Nerve ◽  
Insight Into ◽  
Stimulation Of

Transcutaneous electrical stimulation using kilohertz-frequency alternating current (AC) became popular in the 1950s with the introduction of “interferential currents,” promoted as a means of producing depth-efficient stimulation of nerve and muscle. Later, “Russian current” was adopted as a means of muscle strengthening. This article reviews some clinically relevant, laboratory-based studies that offer an insight into the mechanism of action of kilohertz-frequency AC. It provides some answers to the question: “What are the optimal stimulus parameters for eliciting forceful, yet comfortable, electrically induced muscle contractions?” It is concluded that the stimulation parameters commonly used clinically (Russian and interferential currents) are suboptimal for achieving their stated goals and that greater benefit would be obtained using short-duration (2–4 millisecond), rectangular bursts of kilohertz-frequency AC with a frequency chosen to maximize the desired outcome.

Optical monitoring of neural networks evoked by focal electrical stimulation on microelectrode arrays using FM dyes

2010 ◽  
Vol 48 (9) ◽  
pp. 933-940 ◽  
Author(s):  
Sang Beom Jun ◽  
Karen L. Smith ◽  
William Shain ◽  
Natalie M. Dowell-Mesfin ◽  
Sung June Kim ◽  
...  
Keyword(s):  
Neural Networks ◽  
Electrical Stimulation ◽  
Microelectrode Arrays ◽  
Optical Monitoring ◽  
Fm Dyes

Swimming movements elicited by electrical stimulation of turtle spinal cord. I. Low-spinal and intact preparations

1977 ◽  
Vol 40 (4) ◽  
pp. 768-778 ◽  
Author(s):  
P. R. Lennard ◽  
P. S. Stein
Keyword(s):  
Spinal Cord ◽  
Electrical Stimulation ◽  
Repetition Rate ◽  
Pattern Generator ◽  
Limb Movements ◽  
Data Support ◽  
Stimulus Parameters ◽  
Electrical Pulses ◽  
Dorsolateral Funiculus ◽  
Stimulation Of

1. Electrical stimulation applied within the dorsolateral funiculus of the spinal cord of an intact, unanesthetized turtle can elicit rhythmic limb movements similar to those observed during swimming. 2. A spontaneous display of hindlimb swimming movements is not observed in adult turtles whose spinal cord is transected at D2. Such swimming movements are observed in these "low-spinal" turtles in response to electrical stimulation applied within the dorsolateral funiculus caudad to the transection. 3. The repetition rate of these swimming movements can be altered by changing stimulus parameters, such as the frequency of electrical pulses. 4. The present results indicate that, in the turtle, a neural pattern generator contributing to the production of hindlimb movements during swimming is located mainly in structures caudad to the cervical enlargement of the spinal cord. These data support the hypothesis that a pattern generator for locomotion is largely resident within the spinal cord.

Systematic study of the effects of stimulus parameters and stimulus location on afterdischarges elicited by electrical stimulation in the rat

2013 ◽  
Vol 104 (1-2) ◽  
pp. 17-25 ◽  
Author(s):  
Hiroshi Shigeto ◽  
Atthaporn Boongird ◽  
Kenneth Baker ◽  
Christoph Kellinghaus ◽  
Imad Najm ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Systematic Study ◽  
Stimulus Location ◽  
Stimulus Parameters
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