Short- and long-term bacterial inhibiting effect of high concentrations of glycerol used in the preservation of skin allografts

Burns ◽  
2008 ◽  
Vol 34 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Veroniek S.M. Saegeman ◽  
Nadine L. Ectors ◽  
Daniel Lismont ◽  
Bert Verduyckt ◽  
Jan Verhaegen
2001 ◽  
Vol 2001 ◽  
pp. 141-141
Author(s):  
M.O. Mohammed ◽  
P.C. Chiy ◽  
C. J. C. Phillips

The presence of high concentrations of sodium in the mammalian small intestine plays a major role in facilitating copper absorption (e.g. Wapnir and Stiel, 1987). An experiment was conducted that investigated the medium and long-term effects of adding sodium to the diet of sheep on the copper accumulation in body tissues.


2017 ◽  
Vol 38 (2) ◽  
pp. 175-185 ◽  
Author(s):  
Lara Zácari Fanali ◽  
Bruno Serra de Lacerda Valverde ◽  
Lilian Franco-Belussi ◽  
Diogo B. Provete ◽  
Classius de Oliveira

Anurans are exposed to several pollutants. One of these is benzo[α]pyrene (BaP). This compound is produced by incomplete combustion and is toxic to the liver and intestine, where it is metabolized. Here, we tested how different concentrations of BaP affect the thickness of small intestine and liver melanomacrophages (MMCs) ofHypsiboas albopunctatusduring short- and long-term exposures. We conducted an experiment with a 3 × 2 factorial design to answer these two questions. Male specimens were separated into groups injected with either 3 or 7 mg/kg of BaP and euthanized after either 72 or 168 h. Then, we measured the thickness of the intestinal epithelium and the area occupied by MMCs. The thickness of intestinal epithelium decreased in both high and low concentration for short-term exposure compared to control, and increased in the long-term group in both low and high concentrations. The short-term decrease in thickness is due to the damage caused by BaP on the absorptive capacity of the epithelium, whereas the epithelium increased its thickness and recovered normal activity in the long-term. High BaP concentration decreased the area of MMCs in the short-term group. The increase in MMCs is associated with the detoxifying role of these cells, while the decrease was triggered by cellular stress due to high BaP concentration. The concentrations of BaP we used are close to those found in polluted environments. Therefore, water contaminated with BaP can potentially affect the morphology of internal organs of anurans.


2021 ◽  
Author(s):  
Wadah M. Tashish ◽  
Abdullah S. Aldwayyan ◽  
Hamid M. Ghaithan

Abstract The aim of this study was to investigate the effect of short and long term exposure to N-(phosphonomethyl)glycine (glyphosate) on the photosynthetic activity of Ocimum basilicum L. (basil) plants. Photosynthetic pigment content, chlorophyll fluorescence, and laser-induced chlorophyll fluorescence spectra of basil plants treated for 30, 50, or 70 days with either 0,1, 2, or 3 ml/L (H2O) glyphosate were measured. The ratio of the two fluorescence intensity maxima was calculated by evaluating curve-fitted parameters. Findings revealed that after 30 days of treatment, 1 ml/l (H2O) of glyphosate stimulated, whereas 2 and 3 ml/l (H2O) of glyphosate inhibited, photosynthetic activity of basil plants. In contrast, all tested concentrations of glyphosate became inhibitory after 50 and 70 days of treatment. This study clearly showed that at high concentrations (> 1 ml/l (H2O)), glyphosate is highly toxic to basil. This finding may be helpful for determining the optimal dose of glyphosate in agricultural practices.


Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.


Author(s):  
Ian Neath ◽  
Jean Saint-Aubin ◽  
Tamra J. Bireta ◽  
Andrew J. Gabel ◽  
Chelsea G. Hudson ◽  
...  

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