Chemoselective cross-linking of alginate with thiol-terminated peptides for tissue engineering applications

2012 ◽  
Vol 88 (4) ◽  
pp. 1239-1250 ◽  
Author(s):  
Silvia Bubenikova ◽  
Izabela-Cristina Stancu ◽  
Lucia Kalinovska ◽  
Etienne Schacht ◽  
Evi Lippens ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cross Linking ◽  
Engineering Applications

Cellular Cross-linking of Peptide Modified Hydrogels

2004 ◽  
Vol 127 (2) ◽  
pp. 220-228 ◽  
Author(s):  
Jeanie L. Drury ◽  
Tanyarut Boontheekul ◽  
David J. Mooney
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Cell Density ◽  
Tensile Tests ◽  
Cross Linking ◽  
Engineering Applications ◽  
C2c12 Myoblasts ◽  
Polymer Systems ◽  
Peptide Modification ◽  
Adhesive Interactions

Peptide modification of hydrogel-forming materials is being widely explored as a means to regulate the phenotype of cells immobilized within the gels. Alternatively, we hypothesized that the adhesive interactions between cells and peptides coupled to the gel-forming materials would also enhance the overall mechanical properties of the gels. To test this hypothesis, alginate polymers were modified with RGDSP-containing peptides and the resultant polymer was used to encapsulate C2C12 myoblasts. The mechanical properties of these gels were then assessed as a function of both peptide and cell density using compression and tensile tests. Overall, it was found that above a critical peptide and cell density, encapsulated myoblasts were able to provide additional mechanical integrity to hydrogels composed of peptide-modified alginate. This occurred presumably by means of cell-peptide cross-linking of the alginate polymers, in addition to the usual Ca++ cross-linking. These results are potentially applicable to other polymer systems and important for a range of tissue engineering applications.

Cross-linking methods of electrospun fibrinogen scaffolds for tissue engineering applications

2008 ◽  
Vol 3 (4) ◽  
pp. 045001 ◽  
Author(s):  
Scott A Sell ◽  
Michael P Francis ◽  
Koyal Garg ◽  
Michael J McClure ◽  
David G Simpson ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cross Linking ◽  
Engineering Applications

Role of temperature on bio-printability of gelatin methacryloyl bioink in two-step cross-linking strategy for tissue engineering applications

2020 ◽  
Vol 16 (1) ◽  
pp. 015021
Author(s):  
Mohsen Janmaleki ◽  
Jun Liu ◽  
Milad Kamkar ◽  
Milad Azarmanesh ◽  
Uttandaraman Sundararaj ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cross Linking ◽  
Engineering Applications

Scaffolds and Tissue Engineering Applications by 3D Bio-Printing Process

2021 ◽  
pp. 718-733
Author(s):  
Ranjit Barua ◽  
Sudipto Datta ◽  
Pallab Datta ◽  
Amit Roy Chowdhury
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Manufacturing Process ◽  
Cross Linking ◽  
Engineering Applications ◽  
Printing Process ◽  
Important Thing ◽  
Bone Scaffolds ◽  
Complex Design ◽  
Different Types

3D bio-printing is a revolutionary manufacturing process that is widely used in medical fields especially in preparing bone scaffolds and tissue engineering. With the help of new biocompatible material like polymers, bio-gels, ceramics, this technology has created a new site in advanced tissue engineering and scaffolds manufacturing area. Another important thing is that, with the use of CAD file software, any complex design can be prepared (i.e., this technology does not have any limited sites). But here it is very much essential to study and analyze machine printability characteristics, cross-linking time and biocompatibility of printing objects as well as bio-ink. However, mechanical properties like shear thinning, mechanical elasticity are also required. In this chapter, different types of scaffold-preparing methods and the bio-printing process are discussed, which are used in scaffold and tissue engineering.

Scaffolds and Tissue Engineering Applications by 3D Bio-Printing Process

2019 ◽  
pp. 78-99 ◽  
Author(s):  
Ranjit Barua ◽  
Sudipto Datta ◽  
Pallab Datta ◽  
Amit Roy Chowdhury
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Manufacturing Process ◽  
Cross Linking ◽  
Engineering Applications ◽  
Printing Process ◽  
Important Thing ◽  
Bone Scaffolds ◽  
Complex Design ◽  
Different Types

3D bio-printing is a revolutionary manufacturing process that is widely used in medical fields especially in preparing bone scaffolds and tissue engineering. With the help of new biocompatible material like polymers, bio-gels, ceramics, this technology has created a new site in advanced tissue engineering and scaffolds manufacturing area. Another important thing is that, with the use of CAD file software, any complex design can be prepared (i.e., this technology does not have any limited sites). But here it is very much essential to study and analyze machine printability characteristics, cross-linking time and biocompatibility of printing objects as well as bio-ink. However, mechanical properties like shear thinning, mechanical elasticity are also required. In this chapter, different types of scaffold-preparing methods and the bio-printing process are discussed, which are used in scaffold and tissue engineering.

Self-assembling peptides cross-linked with genipin: resilient hydrogels and self-standing electrospun scaffolds for tissue engineering applications

2019 ◽  
Vol 7 (1) ◽  
pp. 76-91 ◽  
Author(s):  
Raffaele Pugliese ◽  
Mahboubeh Maleki ◽  
Ronald N. Zuckermann ◽  
Fabrizio Gelain
Keyword(s):  
Tissue Engineering ◽  
Cross Linking ◽  
Engineering Applications ◽  
Electrospun Scaffolds ◽  
Self Assembling

Molecular cross-linking with genipin enables the production of resilient standard and electro-spun self-standing scaffolds made of self-assembling peptides.

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